scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1013740220 |
P356 | DOI | 10.1186/S40478-015-0201-7 |
P932 | PMC publication ID | 4382927 |
P698 | PubMed publication ID | 25853389 |
P5875 | ResearchGate publication ID | 274727517 |
P50 | author | Till Milde | Q52148375 |
Thomas Hielscher | Q87639824 | ||
Andrey Korshunov | Q89166780 | ||
Andreas E Kulozik | Q89170845 | ||
Ina Oehme | Q89280944 | ||
Marcel Kool | Q90637389 | ||
Hedwig E Deubzer | Q91874143 | ||
Florian Selt | Q100479794 | ||
Olaf Witt | Q114408281 | ||
Jonas Ecker | Q114726918 | ||
Marco Lodrini | Q114727046 | ||
Stefan M. Pfister | Q39183179 | ||
Andreas von Deimling | Q40381084 | ||
P2093 | author name string | Judit Kiss | |
Ralph Mazitschek | |||
Carina Konrad | |||
P2860 | cites work | Drug development: Raise standards for preclinical cancer research | Q22348097 |
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Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability | Q27679266 | ||
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition | Q27852966 | ||
Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor | Q28140525 | ||
Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci | Q28236937 | ||
Subgroup-specific structural variation across 1,000 medulloblastoma genomes | Q28271811 | ||
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome | Q28298987 | ||
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Believe it or not: how much can we rely on published data on potential drug targets? | Q29547529 | ||
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Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas | Q34167499 | ||
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma | Q34362028 | ||
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Sonic hedgehog-induced histone deacetylase activation is required for cerebellar granule precursor hyperplasia in medulloblastoma | Q34949592 | ||
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Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeuti | Q36222932 | ||
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. | Q36631618 | ||
Evaluation of romidepsin for clinical activity and radioactive iodine reuptake in radioactive iodine-refractory thyroid carcinoma | Q36813563 | ||
Medulloblastoma comprises four distinct molecular variants | Q36920479 | ||
Histone deacetylase 10 promotes autophagy-mediated cell survival. | Q37010515 | ||
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MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma. | Q53201641 | ||
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GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3. | Q39034764 | ||
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma | Q39158975 | ||
HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment. | Q39262034 | ||
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat | Q39485541 | ||
Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors | Q39809571 | ||
HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells. | Q39944234 | ||
Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood | Q40182103 | ||
Evaluation of the antitumor efficacy, pharmacokinetics, and pharmacodynamics of the histone deacetylase inhibitor depsipeptide in childhood cancer models in vivo | Q40333282 | ||
MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors | Q40692665 | ||
Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases | Q42109512 | ||
A proposal regarding reporting of in vitro testing results | Q42552338 | ||
Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays | Q43153279 | ||
Nestin expression identifies ependymoma patients with poor outcome | Q43662312 | ||
Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice | Q46156118 | ||
Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases | Q46727287 | ||
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P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P921 | main subject | medulloblastoma | Q1333608 |
P304 | page(s) | 22 | |
P577 | publication date | 2015-04-03 | |
P1433 | published in | Acta Neuropathologica Communications | Q27724912 |
P1476 | title | Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma | |
P478 | volume | 3 |
Q60047613 | Application of Small Epigenetic Modulators in Pediatric Medulloblastoma |
Q47900778 | Epigenetic regulation in medulloblastoma |
Q37706929 | Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing |
Q38652681 | Evolving molecular era of childhood medulloblastoma: time to revisit therapy |
Q36694288 | HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma |
Q33733042 | HDAC2 overexpression correlates with aggressive clinicopathological features and DNA-damage response pathway of breast cancer |
Q37437368 | HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer |
Q38947405 | HDACs and HDAC Inhibitors in Cancer Development and Therapy |
Q92382697 | Histone deacetylase inhibitors differentially regulate c-Myc expression in retinoblastoma cells |
Q55022167 | Improved therapy for medulloblastoma: targeting hedgehog and PI3K-mTOR signaling pathways in combination with chemotherapy. |
Q38791113 | Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model |
Q92534457 | MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat |
Q91711195 | Methylation Profiling of Medulloblastoma in a Clinical Setting Permits Sub-classification and Reveals New Outcome Predictions |
Q91842359 | Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours |
Q41344917 | Panobinostat, a histone deacetylase inhibitor, suppresses leptomeningeal seeding in a medulloblastoma animal model |
Q91863904 | Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia |
Q36480084 | Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors |
Q36901551 | Risk stratification of childhood medulloblastoma in the molecular era: the current consensus |
Q64389399 | The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines |
Q36288376 | Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups |
Q38817974 | Viability of D283 medulloblastoma cells treated with a histone deacetylase inhibitor combined with bombesin receptor antagonists. |
Q38957110 | Zinc and zinc-containing biomolecules in childhood brain tumors. |
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