Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease

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Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-14-1026
P932PMC publication ID4383679
P698PubMed publication ID25634212

P50authorJane B. LianQ61090559
Hanna TaipaleenmäkiQ61872622
Janet L SteinQ88625564
Gary S SteinQ88625567
Jozef ZustinQ114294035
Eric HesseQ114422906
Jacqueline AkechQ117270528
Andre J van WijnenQ60974897
P2093author name stringGillian Browne
P2860cites workSystemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genesQ24628676
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2Q28505869
Metastasis to bone: causes, consequences and therapeutic opportunitiesQ29614310
miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.Q30407836
First microRNA mimic enters clinicQ87067042
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesionsQ30435146
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasionQ30447945
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell linesQ33377379
MicroRNAs in the control of metastatic bone diseaseQ33821326
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases developmentQ33834762
Mechanisms of bone metastasisQ33977526
Metastatic bone disease: role of transcription factors and future targetsQ34217531
miR-214 targets ATF4 to inhibit bone formation.Q34316430
Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motilityQ34989177
FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasionQ35024427
Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer CellsQ35755187
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive reviewQ36037933
Integrin αvβ3 and CD44 pathways in metastatic prostate cancer cells support osteoclastogenesis via a Runx2/Smad 5/receptor activator of NF-κB ligand signaling axisQ36402883
MicroRNA control of bone formation and homeostasisQ36661323
Signaling between transforming growth factor β (TGF-β) and transcription factor SNAI2 represses expression of microRNA miR-203 to promote epithelial-mesenchymal transition and tumor metastasisQ36760255
Cancer to bone: a fatal attractionQ36884628
MicroRNA functions in osteogenesis and dysfunctions in osteoporosisQ36917893
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cellsQ37000350
MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcomaQ37175182
Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasisQ37322289
Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer.Q37323255
Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progressionQ37343805
Dysregulation of developmental pathways in bone metastasisQ37772654
TGF-β in cancer and bone: implications for treatment of bone metastasesQ37779131
Mechanisms in endocrinology: micro-RNAs: targets for enhancing osteoblast differentiation and bone formationQ37956245
Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomasQ39340986
MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines.Q39582762
Regulatory Role of mir-203 in Prostate Cancer Progression and MetastasisQ39619751
Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathwayQ39956368
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
P304page(s)1433-1444
P577publication date2015-01-29
P1433published inCancer ResearchQ326097
P1476titleTargeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
P478volume75

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cites work (P2860)
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