Targeting the Metastatic Bone Microenvironment by MicroRNAs.

scientific article published on 27 April 2018

Targeting the Metastatic Bone Microenvironment by MicroRNAs. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FENDO.2018.00202
P932PMC publication ID5946017
P698PubMed publication ID29780354

P2093author name stringHanna Taipaleenmäki
Marie-Therese Haider
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
Involvement of chemokine receptors in breast cancer metastasisQ24290909
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expressionQ24683830
MicroRNAs and Osteolytic Bone Metastasis: The Roles of MicroRNAs in Tumor-Induced Osteoclast DifferentiationQ26783571
Targeting the Wnt pathways for therapiesQ26821978
Megakaryocytes, malignancy and bone marrow vascular nichesQ26862087
T cells induce pre-metastatic osteolytic disease and help bone metastases establishment in a mouse model of metastatic breast cancerQ27311542
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cellsQ27860960
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAsQ27861053
Impact of Bone-Targeted Treatments on Skeletal Morbidity and Survival in Breast CancerQ28075195
Tumour-derived miRNAs and bone metastasisQ28086895
Putting tumours in contextQ28207789
miRBase: annotating high confidence microRNAs using deep sequencing dataQ28660701
Export of microRNAs and microRNA-protective protein by mammalian cellsQ29614234
A multigenic program mediating breast cancer metastasis to boneQ29614308
Role of angiogenesis in tumor growth and metastasisQ29614309
Metastasis to bone: causes, consequences and therapeutic opportunitiesQ29614310
The distribution of secondary growths in cancer of the breast. 1889Q29614314
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteinsQ29615034
The MicroRNA Spectrum in 12 Body FluidsQ29618068
miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.Q30407836
Systemic endocrine instigation of indolent tumor growth requires osteopontinQ33343851
MicroRNAs in the control of metastatic bone diseaseQ33821326
Modifying the osteoblastic niche with zoledronic acid in vivo-potential implications for breast cancer bone metastasisQ34024176
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factorsQ34152009
Metastatic bone disease: role of transcription factors and future targetsQ34217531
A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cellsQ34240754
Identification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cellsQ34281856
miR-214 targets ATF4 to inhibit bone formation.Q34316430
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptorQ34480347
Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancerQ34644776
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrowQ34755120
Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone.Q52867416
Mechanisms of bone metastasisQ84730325
Mechanisms in endocrinology: micro-RNAs: targets for enhancing osteoblast differentiation and bone formationQ37956245
New therapeutic targets for cancer bone metastasisQ38473066
Bone Metastasis-Related MicroRNAs: New Targets for Treatment?Q38539474
Skeletal metastases from breast cancer: pathogenesis of bone tropism and treatment strategy.Q38581768
The role of microRNAs in bone metastasisQ38808905
Bone metastasis: the importance of the neighbourhood.Q38843253
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liverQ38873616
miRNA cargo within exosome-like vesicle transfer influences metastatic bone colonization.Q39018734
Location matters: osteoblast and osteoclast distribution is modified by the presence and proximity to breast cancer cells in vivoQ39352902
Circulating microRNAs as novel biomarkers for bone diseases - Complex signatures for multifactorial diseases?Q40366096
Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell functionQ40736018
The role of biomarkers in the management of bone-homing malignancies.Q41692580
Localization of parathyroid hormone-related protein in breast cancer metastases: increased incidence in bone compared with other sitesQ41761675
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in boneQ41881171
MicroRNAs as regulators of tumor-associated stromal cellsQ42506714
Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind studyQ42829926
Distinct bone marrow blood vessels differentially regulate haematopoiesis.Q46564265
Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to ChemotherapyQ47302520
Regulation of Bone Metabolism by microRNAsQ47730978
MicroRNAs and Cancer: A Long Story for Short RNAsQ47839947
Manipulating the environment of cancer cells in bone: a novel therapeutic approachQ34826767
The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cellsQ35079440
Metastatic breast cancer: the potential of miRNA for diagnosis and treatment monitoring.Q35203556
Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone DiseaseQ35251618
PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy targetQ35578573
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitorsQ35621527
Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectivesQ35744492
The Role of Osteoclasts in Early Dissemination of Prostate Cancer Tumor Cells.Q35747744
Dissecting the metastatic cascadeQ35788115
Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell nicheQ35976918
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive reviewQ36037933
miR-214 promotes osteoclastogenesis by targeting Pten/PI3k/Akt pathwayQ36192032
Breast Cancer Cell Colonization of the Human Bone Marrow Adipose Tissue NicheQ36397005
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cellsQ36451980
Osteocyte control of osteoclastogenesisQ36514172
Osteoblastic activation in the hematopoietic stem cell niche.Q36532592
Rapid modification of the bone microenvironment following short-term treatment with Cabozantinib in vivo.Q36621024
MicroRNA control of bone formation and homeostasisQ36661323
Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formationQ36674531
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.Q36682092
Bone marrow cells in the 'pre-metastatic niche': within bone and beyondQ36691234
Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT.Q36731080
Cancer to bone: a fatal attractionQ36884628
The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasitesQ37096553
The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.Q37126990
MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcomaQ37175182
WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growthQ37277156
The perivascular niche regulates breast tumour dormancy.Q37305997
Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasisQ37322289
Bone targeted treatments in cancer - The story so farQ37337487
Osteoclastic miR-214 targets TRAF3 to contribute to osteolytic bone metastasis of breast cancerQ37575983
Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells.Q37684242
Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cellsQ37694746
Dysregulation of developmental pathways in bone metastasisQ37772654
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectmicroRNAQ310899
P304page(s)202
P577publication date2018-04-27
P1433published inFrontiers in EndocrinologyQ27723680
P1476titleTargeting the Metastatic Bone Microenvironment by MicroRNAs.
P478volume9

Reverse relations

cites work (P2860)
Q64992109A novel RNA aptamer identifies plasma membrane ATP synthase beta subunit as an early marker and therapeutic target in aggressive cancer.
Q90655998Brain metastasis-related microRNAs in patients with advanced breast cancer
Q91782750Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
Q92945435Inhibition of CRY2 by STAT3/miRNA-7-5p Promotes Osteoblast Differentiation through Upregulation of CLOCK/BMAL1/P300 Expression
Q92582088MicroRNA‑214 suppresses the viability, migration and invasion of human colorectal carcinoma cells via targeting transglutaminase 2
Q97426733Tumor dormancy in bone
Q61804483miR-135a suppresses migration of gastric cancer cells by targeting TRAF5-mediated NF-κB activation

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