| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/CMDC.201402292 |
| P698 | PubMed publication ID | 25263285 |
| P50 | author | Ronaldo Aloise Pilli | Q37828434 |
| João Ernesto de Carvalho | Q41905156 | ||
| Débora Barbosa Vendramini-Costa | Q41905431 | ||
| P2093 | author name string | João Ernesto de Carvalho | |
| Paula Araújo Monteiro | |||
| Giovanna Barbarini Longato | |||
| Vanessa Caixeta | |||
| Julio Cezar Pastre | |||
| Rosimeire Coura Barcelos | |||
| P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
| RETRACTED: Selective killing of cancer cells by a small molecule targeting the stress response to ROS | Q24607147 | ||
| Tissue distribution and efficacy of gold nanorods coupled with laser induced photoplasmonic therapy in ehrlich carcinoma solid tumor model | Q27304804 | ||
| Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine | Q27666091 | ||
| Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles | Q27678280 | ||
| Reactive oxygen species, cellular redox systems, and apoptosis | Q28393669 | ||
| Drug resistance and the solid tumor microenvironment | Q29614403 | ||
| The NCI60 human tumour cell line anticancer drug screen | Q29614975 | ||
| Topoisomerase I inhibitors: camptothecins and beyond | Q29614976 | ||
| New colorimetric cytotoxicity assay for anticancer-drug screening | Q29615418 | ||
| Natural products as sources of new drugs over the 30 years from 1981 to 2010 | Q29616640 | ||
| Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? | Q29616804 | ||
| Oxidative stress, inflammation, and cancer: how are they linked? | Q29616835 | ||
| Physiological roles of mitochondrial reactive oxygen species | Q29620297 | ||
| Semisynthesis and antitumor activities of new styryl-lactone derivatives | Q33226698 | ||
| Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation. | Q33916713 | ||
| Ascitic and solid Ehrlich tumor inhibition by Chenopodium ambrosioides L. treatment. | Q33991636 | ||
| Microtubule-binding natural products for cancer therapy | Q34122669 | ||
| Synthesis of methoxylated goniothalamin, aza-goniothalamin and γ-pyrones and their in vitro evaluation against human cancer cells | Q34248580 | ||
| Determination of apoptotic and necrotic cell death in vitro and in vivo. | Q34331948 | ||
| The role of glutathione in cancer. | Q34351043 | ||
| Molecular mechanisms of drug resistance | Q34382998 | ||
| Reactive oxygen species in cancer cells: live by the sword, die by the sword. | Q34564435 | ||
| An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells. | Q34582568 | ||
| Discovery of small-molecule enhancers of reactive oxygen species that are nontoxic or cause genotype-selective cell death. | Q34616049 | ||
| Design, synthesis and in vitro evaluation against human cancer cells of 5-methyl-5-styryl-2,5-dihydrofuran-2-ones, a new series of goniothalamin analogues | Q34857235 | ||
| Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress | Q35008361 | ||
| Apoptosis in cancer: from pathogenesis to treatment | Q35397889 | ||
| Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs | Q36279894 | ||
| Beyond annexin V: fluorescence response of cellular membranes to apoptosis | Q36577907 | ||
| Styryl lactones and their derivatives: biological activities, mechanisms of action and potential leads for drug design. | Q36683441 | ||
| Helenanolide-type sesquiterpene lactones--III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules | Q73354884 | ||
| Helenanolide type sesquiterpene lactones. Part 5: the role of glutathione addition under physiological conditions | Q73409154 | ||
| Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells | Q78170671 | ||
| In vitro and in vivo antitumor effect of 5-FU combined with piplartine and piperine | Q80414598 | ||
| Antineoplasic activity of Copaifera multijuga oil and fractions against ascitic and solid Ehrlich tumor | Q81685367 | ||
| The cell cycle and cancer | Q85077091 | ||
| Synthesis and molecular structure of piplartine (=piperlongumine) | Q105282612 | ||
| Haloenol lactone is a new isozyme-selective and active site-directed inactivator of glutathione S-transferase | Q36807276 | ||
| Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches | Q37537958 | ||
| Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death | Q37594392 | ||
| Oxidative stress in apoptosis and cancer: an update. | Q38027434 | ||
| Overview of the therapeutic potential of piplartine (piperlongumine). | Q38067223 | ||
| Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism | Q38516002 | ||
| Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells. | Q39140011 | ||
| Goniothalamin-induced oxidative stress, DNA damage and apoptosis via caspase-2 independent and Bcl-2 independent pathways in Jurkat T-cells | Q39274307 | ||
| Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction. | Q39327284 | ||
| Selective cytotoxicity of goniothalamin against hepatoblastoma HepG2 cells. | Q39562856 | ||
| Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability. | Q39578217 | ||
| Effect of goniothalamin on the development of Ehrlich solid tumor in mice | Q39664802 | ||
| 6-Bicycloaryl substituted (S)- and (R)-5,6-dihydro-2H-pyran-2-ones: asymmetric synthesis, and anti-proliferative properties | Q39913915 | ||
| Cytotoxicity and antitumoral activity of dichloromethane extract and its fractions from Pothomorphe umbellata | Q39973287 | ||
| Caffeic acid and its synthetic derivative CADPE suppress tumor angiogenesis by blocking STAT3-mediated VEGF expression in human renal carcinoma cells | Q40122216 | ||
| Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. | Q40234453 | ||
| Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells | Q40366203 | ||
| Cytotoxic activity of (S)-goniothalamin and analogues against human cancer cells | Q40366240 | ||
| (R)-Goniothalamin: total syntheses and cytotoxic activity against cancer cell lines | Q40444299 | ||
| Anticancer activity of phenolic acids of natural or synthetic origin: a structure-activity study. | Q40613138 | ||
| Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells | Q40658370 | ||
| Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines | Q41679901 | ||
| The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transport | Q43104351 | ||
| The activity against Ehrlich's ascites tumors of doxorubicin contained in self assembled, cell receptor targeted nanoparticle with simultaneous oral delivery of the green tea polyphenol epigallocatechin-3-gallate | Q43683984 | ||
| The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells | Q43706732 | ||
| Effect of beta-Carotene on the development of the solid Ehrlich tumor in mice | Q44033259 | ||
| Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells | Q44505547 | ||
| Synthesis and biological evaluation of cytostatin analogues | Q44558292 | ||
| Kava lactones and the kava-kava controversy | Q44588233 | ||
| Inhibitory effect of caffeic acid phenethyl ester on angiogenesis, tumor invasion, and metastasis | Q44702669 | ||
| Effects produced by Royal Jelly on haematopoiesis: relation with host resistance against Ehrlich ascites tumour challenge | Q45264529 | ||
| Structural and functional consequences of haloenol lactone inactivation of murine and human glutathione S-transferase | Q46055726 | ||
| Cytotoxicity of goniothalamin enantiomers in renal cancer cells: involvement of nitric oxide, apoptosis and autophagy. | Q46389537 | ||
| Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition | Q46435326 | ||
| Goniothalamin induces apoptosis in vascular smooth muscle cells | Q46811852 | ||
| In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper. | Q51801735 | ||
| Fredericamycin A, a new antitumor antibiotic. I. Production, isolation and physicochemical properties | Q71581923 | ||
| P433 | issue | 12 | |
| P304 | page(s) | 2725-2743 | |
| P577 | publication date | 2014-09-26 | |
| P1433 | published in | ChemMedChem | Q2962252 |
| P1476 | title | Design and synthesis of N-acylated aza-goniothalamin derivatives and evaluation of their in vitro and in vivo antitumor activity | |
| P478 | volume | 9 |
| Q47160621 | Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis |
| Q89821211 | Rapid, two-pot procedure for the synthesis of dihydropyridinones; total synthesis of aza-goniothalamin |
| Q91506866 | Synthesis of Nitrogen-Containing Goniothalamin Analogues with Higher Cytotoxic Activity and Selectivity against Cancer Cells |
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