Complexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus.

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Complexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus. is …
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scholarly articleQ13442814

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P356DOI10.1021/BI201302W
P953full work available at URLhttps://europepmc.org/articles/pmc3194008?pdf=render
P932PMC publication ID3194008
P698PubMed publication ID21899262
P5875ResearchGate publication ID51620563

P7228access restriction statusopen accessQ232932
P50authorBradley S EvansQ56517304
Xue GaoQ79801301
P2093author name stringYi Tang
Christopher T Walsh
Neil L Kelleher
Brian D Ames
Stuart W Haynes
P2860cites workGenomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatusQ21972844
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Anthranilate-activating modules from fungal nonribosomal peptide assembly linesQ33787584
Fungal indole alkaloid biosynthesis: genetic and biochemical investigation of the tryptoquialanine pathway in Penicillium aethiopicumQ34163017
Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the generation of multicyclic scaffolds in fungal indole alkaloid biosynthesisQ34425191
Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites.Q35058923
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The growing VAO flavoprotein family.Q37086580
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Oxidation of amines by flavoproteinsQ37570693
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Transcriptional profiling identifies a role for BrlA in the response to nitrogen depletion and for StuA in the regulation of secondary metabolite clusters in Aspergillus fumigatusQ41876126
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Berberine bridge enzyme, a key branch-point enzyme in benzylisoquinoline alkaloid biosynthesis, contains a vacuolar sorting determinantQ43808238
Cottoquinazoline A and cotteslosins A and B, metabolites from an Australian marine-derived strain of Aspergillus versicolor.Q46107987
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Aryl-alcohol oxidase protein sequence: a comparison with glucose oxidase and other FAD oxidoreductasesQ46717835
Metabolomics ofAspergillus fumigatusQ59140450
Fusion PCR and gene targeting in Aspergillus nidulansQ62658531
New Quinazolinone Alkaloids within Rare Amino Acid Residue from Coral-Associated Fungus,Aspergillus versicolorLCJ-5-4Q78443757
Nitrogen kinetic isotope effects for the monoamine oxidase B-catalyzed oxidation of benzylamine and (1,1-(2)H2)benzylamine: nitrogen rehybridization and CH bond cleavage are not concertedQ84591210
P433issue40
P407language of work or nameEnglishQ1860
P921main subjectAspergillus fumigatusQ134359
fumiquinazoline AQ27133341
fumiquinazoline FQ27133342
fumiquinazoline CQ27133343
nonribosomal peptide synthetase 11Q61579616
putative monooxygenase (FAD)Q61579705
flavoprotein amide oxidase (FAD)Q61579736
nonribosomal peptide synthetase 12Q61579771
P6954online access statusopen accessQ232932
P304page(s)8756-8769
P577publication date2011-09-19
P1433published inBiochemistryQ764876
P1476titleComplexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus
P478volume50