Smad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycans

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Smad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycans is …
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scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2011.07470.X
P932PMC publication ID3197872
P698PubMed publication ID21895657
P5875ResearchGate publication ID51623093

P50authorHerbert M GellerQ57039601
Pan-pan YuQ80203787
Aviva J SymesQ40014197
P2093author name stringBala T S Susarla
Yasuhiro Katagiri
Eric D Laing
P2860cites workMolecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-IIQ24290566
Molecular cloning and expression of a human chondroitin synthaseQ24291588
Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4Q24297637
New insights into TGF-beta-Smad signallingQ28260517
Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissueQ28566378
Versican is upregulated in CNS injury and is a product of oligodendrocyte lineage cellsQ28571974
Expression of TGFbeta2 but not TGFbeta1 correlates with the deposition of scar tissue in the lesioned spinal cordQ48584785
A simple procedure for quantification of neurite outgrowth based on stereological principles.Q52072482
Increases in transforming growth factor-beta mRNA in hippocampus during response to entorhinal cortex lesions in intact and adrenalectomized ratsQ70170231
Biphasic transforming growth factor-beta production flanking the pro-inflammatory cytokine response in cerebral traumaQ71351203
Neurocan is upregulated in injured brain and in cytokine-treated astrocytesQ73575576
Localization of transforming growth factor-beta1 and receptor mRNA after experimental spinal cord injuryQ73721201
Transcriptional regulation of scar gene expression in primary astrocytesQ80539435
Endogenous transforming growth factor beta 1 suppresses inflammation and promotes survival in adult CNSQ81454098
Altered production and proteolytic processing of brevican by transforming growth factor beta in cultured astrocytesQ28578848
Deoxyribozyme-mediated knockdown of xylosyltransferase-1 mRNA promotes axon growth in the adult rat spinal cordQ28582743
Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryoQ28586864
Chondroitinase ABC promotes functional recovery after spinal cord injuryQ29615017
Non-Smad pathways in TGF-beta signalingQ29620040
Chondroitin-4-sulfation negatively regulates axonal guidance and growthQ30483928
Inhibition of glial scarring in the injured rat brain by a recombinant human monoclonal antibody to transforming growth factor-beta2.Q30724603
Structural characterization of the epitopes of the monoclonal antibodies 473HD, CS-56, and MO-225 specific for chondroitin sulfate D-type using the oligosaccharide library.Q33210460
Glycosaminoglycan (GAG) Biosynthesis and GAG-Binding ProteinsQ33391706
Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injuryQ33734430
Synthesis and sorting of proteoglycansQ33816005
Diversity and functions of glycosaminoglycan sulfotransferasesQ33878520
Molecular Cloning of a Chondroitin Polymerizing Factor That Cooperates with Chondroitin Synthase for Chondroitin PolymerizationQ34193037
Sulfotransferases in glycosaminoglycan biosynthesisQ34271228
Non-Smad TGF-beta signalsQ34443708
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous systemQ34601728
Enhanced expression of transforming growth factor beta 1 in the rat brain after a localized cerebral injuryQ35026906
Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting propertiesQ36234537
Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.Q36258971
CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failureQ36499527
Immunohistochemical localization of chondroitin sulfate in the forestomach of the sheepQ36822996
How the Smads regulate transcriptionQ37025325
A 'GAG' reflex prevents repair of the damaged CNS.Q37026388
New regulatory mechanisms of TGF-beta receptor functionQ37569258
The regulation of TGFbeta signal transductionQ37621155
Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC.Q38524950
Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycansQ40030617
Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes.Q40412316
Smad2 role in mesoderm formation, left-right patterning and craniofacial developmentQ41027581
Proteoglycans provide neurite guidance at an astrocyte boundary.Q41137364
Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblastsQ43550271
Regulation of RPTPbeta/phosphacan expression and glycosaminoglycan epitopes in injured brain and cytokine-treated glia.Q44707559
Transforming growth factor-beta1 upregulates keratan sulfate and chondroitin sulfate biosynthesis in microglias after brain injuryQ48004020
Effects of transforming growth factor beta 1 on scar production in the injured central nervous system of the rat.Q48167252
Isolation and characterization of immature oligodendrocyte lineage cellsQ48267546
Smad3 null mice display more rapid wound closure and reduced scar formation after a stab wound to the cerebral cortexQ48415397
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P1104number of pages11
P304page(s)868-878
P577publication date2011-10-03
P1433published inJournal of NeurochemistryQ6295643
P1476titleSmad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycans
P478volume119

Reverse relations

cites work (P2860)
Q923705482-arachidonoylglycerol reduces chondroitin sulphate proteoglycan production by astrocytes and enhances oligodendrocyte differentiation under inhibitory conditions
Q35865445A Sativex(®) -like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis
Q89700552Ageing affects chondroitin sulfates and their synthetic enzymes in the intervertebral disc
Q48114525Altered Sodium and Potassium, but not Calcium Currents in Cerebellar Granule Cells in an In Vitro Model of Neuronal Injury
Q27313217Arylsulfatase B improves locomotor function after mouse spinal cord injury
Q36355088Astrogliosis during acute and chronic cuprizone demyelination and implications for remyelination
Q26852511BMP signaling in axon regeneration
Q36208997Bone morphogenetic protein-2-mediated pain and inflammation in a rat model of posterolateral arthrodesis
Q30528431Candesartan, an angiotensin II AT₁-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice.
Q35893779Decline in arylsulfatase B and Increase in chondroitin 4-sulfotransferase combine to increase chondroitin 4-sulfate in traumatic brain injury
Q49397380Environmental cues determine the fate of astrocytes after spinal cord injury
Q47682570Fibrotic scar model and TGF-β1 differently modulate action potential firing and voltage-dependent ion currents in hippocampal neurons in primary culture.
Q43833906LPS antagonism of TGF-β signaling results in prolonged survival and activation of rat primary microglia
Q94463932Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model In Vitro
Q47852927Microglial Activation Results in Inhibition of TGF-β-Regulated Gene Expression
Q53621903Neuronal and astroglial TGFβ-Smad3 signaling pathways differentially regulate dendrite growth and synaptogenesis.
Q57498281Portrait of glial scar in neurological diseases
Q36714324Possible mechanical roles of glycosaminoglycans in thoracic aortic dissection and associations with dysregulated transforming growth factor-β.
Q50746245Primary hippocampal neurons, which lack four crucial extracellular matrix molecules, display abnormalities of synaptic structure and function and severe deficits in perineuronal net formation.
Q49357667RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke.
Q36968383Roles of chondroitin sulfate and dermatan sulfate in the formation of a lesion scar and axonal regeneration after traumatic injury of the mouse brain
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Q33786509Targeted inhibition of KCa3.1 attenuates TGF-β-induced reactive astrogliosis through the Smad2/3 signaling pathway
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Q34221930Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis

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