scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M102382200 |
P698 | PubMed publication ID | 11262418 |
P2093 | author name string | Weinstein M | |
Roberts AB | |||
Kucherlapati R | |||
Deng C | |||
Heyer J | |||
Piek E | |||
Stewart CL | |||
Ju WJ | |||
Escalante-Alcalde D | |||
Bottinger EP | |||
P433 | issue | 23 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 19945-19953 | |
P577 | publication date | 2001-03-21 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts | |
P478 | volume | 276 |
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Q38319449 | A dual AP-1 and SMAD decoy ODN suppresses tissue fibrosis and scarring in mice |
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Q34989137 | A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland |
Q42828663 | Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response |
Q28476430 | Activation of protein serine/threonine phosphatase PP2Cα efficiently prevents liver fibrosis |
Q39664271 | Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells |
Q44382985 | Activin a signaling induces Smad2, but not Smad3, requiring protein kinase a activity in granulosa cells from the avian ovary |
Q24307781 | Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium |
Q73947582 | Alpha-helix 2 in the amino-terminal mad homology 1 domain is responsible for specific DNA binding of Smad3 |
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Q40597763 | Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. |
Q46745865 | Angiotensin-converting enzyme inhibitors: a new mechanism of action. |
Q36837922 | Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis. |
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Q24685123 | Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling |
Q36625618 | Betulinic acid enhances TGF-β signaling by altering TGF-β receptors partitioning between lipid-raft/caveolae and non-caveolae membrane microdomains in mink lung epithelial cells |
Q91907218 | Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms |
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Q36850396 | Calreticulin regulates transforming growth factor-β-stimulated extracellular matrix production |
Q28183423 | Cell-Type-Specific Activation of PAK2 by Transforming Growth Factor β Independent of Smad2 and Smad3 |
Q47556336 | Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels |
Q60921030 | Concentrated growth factor exudate enhances the proliferation of human periodontal ligament cells in the presence of TNF‑α |
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Q40190677 | Critical involvement of ILK in TGFbeta1-stimulated invasion/migration of human ovarian cancer cells is associated with urokinase plasminogen activator system |
Q38798056 | Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway |
Q55036249 | DMSO Enhances TGF-β Activity by Recruiting the Type II TGF-β Receptor From Intracellular Vesicles to the Plasma Membrane. |
Q42130956 | Developmentally regulated SMAD2 and SMAD3 utilization directs activin signaling outcomes. |
Q44957645 | Differential proliferative response of fetal and adult human skin fibroblasts to transforming growth factor-beta |
Q24297637 | Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4 |
Q37339311 | Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells |
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Q24302117 | Disabled-2 (Dab2) mediates transforming growth factor beta (TGFbeta)-stimulated fibronectin synthesis through TGFbeta-activated kinase 1 and activation of the JNK pathway |
Q34363558 | Disabled-2 downregulation promotes epithelial-to-mesenchymal transition |
Q91992825 | Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart |
Q37934555 | Diverse roles of TGF-β/Smads in renal fibrosis and inflammation |
Q30352305 | Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract. |
Q34022613 | Dynamics of TGF-β/Smad signaling |
Q41091738 | ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells. |
Q91690318 | Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies |
Q34589649 | Effects of TRAP-1-like protein (TLP) gene on collagen synthesis induced by TGF-β/Smad signaling in human dermal fibroblasts |
Q36736835 | Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis. |
Q74601263 | Endless healing: TGF-beta, SMADs, and fibrosis |
Q35082779 | Endothelial dysfunction exacerbates renal interstitial fibrosis through enhancing fibroblast Smad3 linker phosphorylation in the mouse obstructed kidney. |
Q40689600 | Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest. |
Q34575283 | Essential role of Smad3 in angiotensin II-induced vascular fibrosis |
Q36137054 | Euphol from Euphorbia tirucalli Negatively Modulates TGF-β Responsiveness via TGF-β Receptor Segregation inside Membrane Rafts. |
Q35087770 | Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali |
Q33281716 | Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells. |
Q37170606 | FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate |
Q89473739 | Fibromodulin reduces scar formation in adult cutaneous wounds by eliciting a fetal-like phenotype |
Q58596832 | Fibronectin regulates growth factor signaling and lens cell differentiation |
Q53625350 | Functional characterization of TRAP1-like protein involved in modulating fibrotic processes mediated by TGF-β/Smad signaling in hypertrophic scar fibroblasts. |
Q34085928 | Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair |
Q39212760 | Functional roles of TGF-β1 in intestinal epithelial cells through Smad-dependent and non-Smad pathways |
Q98164841 | GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition |
Q40632467 | Glycosylphosphatidylinositol-anchored proteins regulate transforming growth factor-beta signaling in human keratinocytes |
Q35917938 | Hierarchical model of gene regulation by transforming growth factor beta |
Q92853946 | Human Skin Keratinocytes on Sustained TGF-β Stimulation Reveal Partial EMT Features and Weaken Growth Arrest Responses |
Q41435242 | Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages |
Q39768636 | Hypoxia-activated Smad3-specific dephosphorylation by PP2A. |
Q24338850 | Identification of CD109 as part of the TGF-beta receptor system in human keratinocytes |
Q28186138 | Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta |
Q24336739 | Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1 |
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Q40417137 | Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3. |
Q40733139 | Interaction between the transforming growth factor-beta type II receptor/Smad pathway and beta-catenin during transforming growth factor-beta1-mediated adherens junction disassembly |
Q35843231 | Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin |
Q24294858 | Interleukin-4 regulates connective tissue growth factor expression in human lung fibroblasts |
Q38350220 | Intracellular dynamics of Smad‐mediated TGFβ signaling |
Q37083919 | Involvement of Cyclic Guanosine Monophosphate-Dependent Protein Kinase I in Renal Antifibrotic Effects of Serelaxin |
Q38339058 | Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes |
Q36978251 | LOXL4 is induced by transforming growth factor β1 through Smad and JunB/Fra2 and contributes to vascular matrix remodeling. |
Q37497085 | Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11. |
Q24313188 | Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling |
Q57030301 | LncRNAs in TGF-β-Driven Tissue Fibrosis |
Q37420405 | Local CXCR4 Upregulation in the Injured Arterial Wall Contributes to Intimal Hyperplasia |
Q39084502 | Loss of miR-140 is a key risk factor for radiation-induced lung fibrosis through reprogramming fibroblasts and macrophages |
Q53373344 | Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer. |
Q39373799 | MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype |
Q33804105 | Mechanisms of the epithelial-mesenchymal transition by TGF-beta |
Q52585581 | Mesenchymal transition in kidney collecting duct epithelial cells. |
Q40773532 | Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. |
Q35788867 | Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation |
Q44454818 | Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy |
Q41609683 | Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass |
Q37233285 | MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3 |
Q34031843 | Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression |
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Q35916282 | Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice |
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Q37660994 | Pentabromophenol suppresses TGF-β signaling by accelerating degradation of type II TGF-β receptors via caveolae-mediated endocytosis |
Q44659145 | Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival |
Q34049791 | Phosphoproteome profiling of transforming growth factor (TGF)-beta signaling: abrogation of TGFbeta1-dependent phosphorylation of transcription factor-II-I (TFII-I) enhances cooperation of TFII-I and Smad3 in transcription. |
Q46702673 | Prevention of chronic allograft nephropathy with vitamin D. |
Q44130958 | Proteasomal activity modulates TGF-ss signaling in a gene-specific manner |
Q37734892 | Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness. |
Q28508588 | RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta |
Q42834300 | Receptor-activated Smad localisation in bleomycin-induced pulmonary fibrosis |
Q40468941 | Recognition of phosphorylated-Smad2-containing complexes by a novel Smad interaction motif |
Q30439551 | Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo. |
Q42806698 | Regulation of fibronectin gene expression in cardiac fibroblasts by scleraxis |
Q36049119 | Repressed TGF-β signaling through CagA-Smad3 interaction as pathogenic mechanisms of Helicobacter pylori-associated gastritis |
Q37045195 | Requirement for protein kinase A in the phosphorylation of the TGFβ receptor-interacting protein km23-1 as a component of TGFβ downstream effects |
Q80125616 | Requirement for the dynein light chain km23-1 in a Smad2-dependent transforming growth factor-beta signaling pathway |
Q33898042 | Requirement of a dynein light chain in TGFbeta/Smad3 signaling |
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Q43882371 | Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice |
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