Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells.

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Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1048859846
P356DOI10.1186/1471-2164-8-98
P932PMC publication ID1858692
P698PubMed publication ID17425807
P5875ResearchGate publication ID51389980

P50authorRavi Kiran Reddy KalathurQ55755978
Takashi TakahashiQ56945207
P2093author name stringPaturu Kondaiah
Prathibha Ranganathan
Aravinda K Chavalmane
Animesh Agrawal
Raghu Bhushan
P2860cites workSmad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcriptionQ24311810
Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasisQ24679619
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Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblastsQ24804612
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Smad-dependent and Smad-independent pathways in TGF-beta family signallingQ28208250
How cells read TGF-beta signalsQ29619993
Activated alpha 2-macroglobulin reverses the immunosuppressive activity in human breast cancer cell-conditioned medium by selectively neutralizing transforming growth factor-beta in the presence of interleukin-2.Q30471974
Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responsesQ30476201
Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesisQ33868837
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathwayQ33890533
Association of mitogen-activated protein kinase with the microtubule cytoskeletonQ33934584
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225)Q33937674
Substantial changes in gene expression of Wnt, MAPK and TNFalpha pathways induced by TGF-beta1 in cervical cancer cell linesQ34416684
Non-Smad TGF-beta signalsQ34443708
Function of cytokines within the TGF-beta superfamily as determined from transgenic and gene knockout studies in miceQ34663767
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.Q34792468
Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effectsQ34792580
Microarray identifies ADAM family members as key responders to TGF-beta1 in alveolar epithelial cellsQ35038917
The two faces of transforming growth factor beta in carcinogenesisQ35170231
PI3K/Akt signalling pathway and cancer.Q35692250
Dual role of transforming growth factor beta in mammary tumorigenesis and metastatic progression.Q36035342
Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-betaQ36218283
Genetic programs of epithelial cell plasticity directed by transforming growth factor-betaQ36232185
Alterations in components of the TGF-beta superfamily signaling pathways in human cancerQ36323395
Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.Q36564164
Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.Q38302488
Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1.Q38357026
TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cellsQ38516130
Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells.Q40243334
Identification of apoptotic genes mediating TGF-beta/Smad3-induced cell death in intestinal epithelial cells using a genomic approachQ40244813
The relationship between bone metastasis from human breast cancer and integrin alpha(v)beta3 expression.Q40437776
Role of ERK1/2 and p38 mitogen-activated protein kinases in the regulation of thrombospondin-1 by TGF-beta1 in rat proximal tubular cells and mouse fibroblasts.Q40457216
Differential activation of Smads in HeLa and SiHa cells that differ in their response to transforming growth factor-betaQ40546736
alpha(v)beta(3) Integrin interacts with the transforming growth factor beta (TGFbeta) type II receptor to potentiate the proliferative effects of TGFbeta1 in living human lung fibroblastsQ40547538
Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogeneQ40559849
Fetal liver stroma consists of cells in epithelial-to-mesenchymal transitionQ40680236
Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathwayQ40874515
Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cellsQ40998147
Establishment of human peripheral lung epithelial cell lines (HPL1) retaining differentiated characteristics and responsiveness to epidermal growth factor, hepatocyte growth factor, and transforming growth factor beta1.Q41081957
Urokinase-receptor biosynthesis, mRNA level and gene transcription are increased by transforming growth factor beta 1 in human A549 lung carcinoma cellsQ41083036
Thrombospondin-1 (TSP-1) promotes the invasive properties of human breast cancerQ41195958
Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblastsQ43550271
Integrin-linked kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transitionQ44814280
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticityQ45405811
Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblastsQ46815041
Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumorsQ48445033
Increasing complexity of Ras signaling.Q53429989
Promoter sequences of the human transforming growth factor-beta 1 gene responsive to transforming growth factor-beta 1 autoinductionQ69588815
Immunodetection and quantitation of the two forms of transforming growth factor-beta (TGF-beta 1 and TGF-beta 2) secreted by cells in cultureQ69936661
Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cellsQ70377223
The effect of TGF-beta1 on differential gene expression profiles in human corneal epithelium studied by cDNA expression arrayQ74114723
Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-beta signaling in dermal fibroblasts derived from localized sclerodermaQ83289786
P407language of work or nameEnglishQ1860
P304page(s)98
P577publication date2007-04-11
P1433published inBMC GenomicsQ15765854
P1476titleExpression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells
P478volume8

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