The Epstein-Barr virus latent membrane protein 1 and transforming growth factor--β1 synergistically induce epithelial--mesenchymal transition in lung epithelial cells.

scientific article published on 6 August 2010

The Epstein-Barr virus latent membrane protein 1 and transforming growth factor--β1 synergistically induce epithelial--mesenchymal transition in lung epithelial cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1165/RCMB.2009-0232OC
P932PMC publication ID3135845
P698PubMed publication ID20693406
P5875ResearchGate publication ID45538015

P50authorBin ShanQ42738140
Takashi TakahashiQ56945207
P2093author name stringZhen Lin
Erik K Flemington
Joseph A Lasky
Hong T Nguyen
Ross C Klingsberg
Mark D Sides
Kristin A Gordon
P2860cites workLatent herpesvirus infection augments experimental pulmonary fibrosisQ39342306
Alveolar epithelial cell injury with Epstein-Barr virus upregulates TGFbeta1 expression.Q39962123
Transforming growth factor-beta1 induces heparan sulfate 6-O-endosulfatase 1 expression in vitro and in vivoQ39978694
Epstein-Barr virus-encoded LMP1 regulates epithelial cell motility and invasion via the ERK-MAPK pathwayQ40024497
Comparative analysis of signal transduction by CD40 and the Epstein-Barr virus oncoprotein LMP1 in vivoQ40274082
Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cellsQ40495577
RECK is a target of Epstein–Barr virus latent membrane protein 1Q40616852
Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignanciesQ40623874
Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodelingQ40687983
Establishment of human peripheral lung epithelial cell lines (HPL1) retaining differentiated characteristics and responsiveness to epidermal growth factor, hepatocyte growth factor, and transforming growth factor beta1.Q41081957
Epstein-Barr virus latent membrane protein inhibits human epithelial cell differentiationQ41736955
Cryptogenic fibrosing alveolitis and Epstein-Barr virus: an association?Q44307938
The detection of Epstein-Barr virus DNA in lung tissue from patients with idiopathic pulmonary fibrosisQ45750246
American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)Q73445075
Elevation of antibodies to cytomegalovirus and other herpes viruses in pulmonary fibrosisQ73734162
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traitsQ77103881
MMP expression and abnormal lung permeability are important determinants of outcome in IPFQ82176972
Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinomaQ24298635
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activationQ24316905
Complete sequence and genomic analysis of murine gammaherpesvirus 68Q24672530
TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)Q24813751
Mechanisms of TGF-beta signaling from cell membrane to the nucleusQ27860785
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumoniasQ28143296
Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapyQ28200083
Regulation of immune responses by TGF-betaQ28271433
Cytoplasmic PML function in TGF-beta signallingQ28281152
Complex networks orchestrate epithelial-mesenchymal transitionsQ29547478
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrixQ29619797
Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells.Q33281716
Epstein-Barr virus replication within pulmonary epithelial cells in cryptogenic fibrosing alveolitis.Q33605234
Epstein-Barr virus gH is essential for penetration of B cells but also plays a role in attachment of virus to epithelial cellsQ33807504
Epithelial origin of myofibroblasts during fibrosis in the lungQ33996286
The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferasesQ34099074
LMP1 structure and signal transductionQ34415978
TGF-beta-induced EMT: mechanisms and implications for fibrotic lung diseaseQ34581113
Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathwaysQ34721581
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitroQ34928535
Herpesvirus DNA is consistently detected in lungs of patients with idiopathic pulmonary fibrosisQ35027515
Involvement of Epstein-Barr virus latent membrane protein 1 in disease progression in patients with idiopathic pulmonary fibrosisQ35533486
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient miceQ35855163
Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic miceQ36327458
Regulation of matrix metalloproteinase gene expressionQ36682744
Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition.Q36777948
Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancerQ38300727
P433issue6
P921main subjectEpstein–Barr virusQ6900
membrane proteinQ423042
P304page(s)852-862
P577publication date2010-08-06
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleThe Epstein-Barr virus latent membrane protein 1 and transforming growth factor--β1 synergistically induce epithelial--mesenchymal transition in lung epithelial cells
P478volume44

Reverse relations

cites work (P2860)
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