Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition.

scientific article published on 13 January 2015

Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/CIRCRESAHA.116.305629
P932PMC publication ID4344885
P698PubMed publication ID25587097

P50authorBjörn TampeQ82471123
P2093author name stringRaghu Kalluri
Michael Zeisberg
Xingbo Xu
Pedro J Del Nido
Ivan Melnychenko
Ingeborg Friehs
Elisabeth M Zeisberg
Maria Iascone
Fouzi Alnour
Tachi Zhong Hu
P2860cites workIdentification of de novo mutations and rare variants in hypoplastic left heart syndromeQ24298680
Nebulette Mutations Are Associated With Dilated Cardiomyopathy and Endocardial FibroelastosisQ24303466
Development of heart valves requires Gata4 expression in endothelial-derived cellsQ27863348
TGF-beta signalling from cell membrane to nucleus through SMAD proteinsQ28131770
Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septumQ82267192
Assessment of left ventricular endocardial fibroelastosis in fetuses with aortic stenosis and evolving hypoplastic left heart syndromeQ82711343
Smads: transcriptional activators of TGF-beta responsesQ28292325
Viral infection of the myocardium in endocardial fibroelastosis. Molecular evidence for the role of mumps virus as an etiologic agentQ28301097
Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroupQ28506935
Connexin43 knockdown accelerates wound healing but inhibits mesenchymal transition after corneal endothelial injury in vivoQ28565177
TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-AQ28591018
How cells read TGF-beta signalsQ29619993
Endothelial-to-mesenchymal transition contributes to cardiac fibrosisQ29620566
Left ventricular dysfunction in the fetus: relation to aortic valve anomalies and endocardial fibroelastosisQ33611820
Human Cytomegalovirus Induces TGF-β1 Activation in Renal Tubular Epithelial Cells after Epithelial-to-Mesenchymal TransitionQ33747809
Cardiac fibroblasts in pressure overload hypertrophy: the enemy within?Q33808274
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP).Q33823445
Regulation of Smad activityQ33830190
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Identification of connexin43 (alpha1) gap junction gene mutations in patients with hypoplastic left heart syndrome by denaturing gradient gel electrophoresis (DGGE).Q34084928
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformationQ34301631
Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT).Q34490499
Bmp2 instructs cardiac progenitors to form the heart-valve-inducing fieldQ34531276
Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndromeQ34531285
Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinomaQ34745799
Endocardial fibroelastosis: old and new conceptsQ35649718
An animal model of endocardial fibroelastosisQ36472884
The contribution of de novo and rare inherited copy number changes to congenital heart disease in an unselected sample of children with conotruncal defects or hypoplastic left heart diseaseQ37432642
Primary left ventricular rehabilitation is effective in maintaining two-ventricle physiology in the borderline left heartQ37455331
Rare variants in NR2F2 cause congenital heart defects in humansQ37693348
Left ventricular hypoplasia: a spectrum of disease involving the left ventricular outflow tract, aortic valve, and aortaQ37970840
Staged left ventricular recruitment after single-ventricle palliation in patients with borderline left heart hypoplasiaQ38051803
Novel SMAD3 Mutation in a Patient with Hypoplastic Left Heart Syndrome with Significant Aortic Aneurysm.Q38565616
The Epstein-Barr virus latent membrane protein 1 and transforming growth factor--β1 synergistically induce epithelial--mesenchymal transition in lung epithelial cells.Q39669856
Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cellsQ39939184
Molecular regulation of atrioventricular valvuloseptal morphogenesisQ40549504
Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouseQ41831039
Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signalingQ42361373
Mouse snail is a target gene for HIF.Q51551534
Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis.Q52116730
TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart.Q52178122
Identification of an autocrine signaling pathway that amplifies induction of endocardial cushion tissue in the avian heart.Q52182831
Congenital fibro-elastosis of the endocardiumQ73103102
Changes in left heart hemodynamics after technically successful in-utero aortic valvuloplastyQ80975936
P433issue5
P921main subjectendotheliumQ111140
endocardial fibroelastosisQ5376225
P304page(s)857-866
P577publication date2015-01-13
P1433published inCirculation ResearchQ2599020
P859sponsorCollaborative Research Centre (CRC) 1002: "Modulatory Units in Heart Failure"Q48693816
P1476titleEndocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition
P478volume116

Reverse relations

cites work (P2860)
Q36561215A mouse model of endocardial fibroelastosis
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Q54982965Endothelial to Mesenchymal Transition Represents a Key Link in the Interaction between Inflammation and Endothelial Dysfunction.
Q26752901Endothelial-Mesenchymal Transition in Regenerative Medicine
Q47951267Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium
Q58695373High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis
Q93063229Human Umbilical Cord Mesenchymal Stem Cells Alleviate Myocardial Endothelial-Mesenchymal Transition in a Rat Dilated Cardiomyopathy Model
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