FoxO6 integrates insulin signaling with gluconeogenesis in the liver.

scientific article

FoxO6 integrates insulin signaling with gluconeogenesis in the liver. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2337/DB11-0548
P932PMC publication ID3198083
P698PubMed publication ID21940782
P5875ResearchGate publication ID51664286

P50authorStephen C StromQ40919746
German PerdomoQ47504458
Roberto GramignoliQ56395635
Hengjiang DongQ73409468
Sandra SlusherQ114725745
Steven RingquistQ114725746
P2093author name stringTing Zhang
Yong Fan
Sojin Lee
Dae Hyun Kim
Nick Giannoukakis
Brett E Phillips
P2860cites workFoxo1 mediates insulin action on apoC-III and triglyceride metabolism.Q40301333
Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.Q40609126
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liverQ48386175
Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA bindingQ24306703
Structural basis for leucine-rich nuclear export signal recognition by CRM1Q24604395
Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational ModificationQ27652102
Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTPQ27655147
FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttlingQ28258996
Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemiaQ28365783
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamicsQ28504819
FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in miceQ28507512
Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesisQ28511396
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interactionQ29619822
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transportQ33292269
14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.Q33439373
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy stateQ33968008
FoxOs function synergistically to promote glucose productionQ34284954
Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRL1 and AFX.Q34797172
FoxOs at the crossroads of cellular metabolism, differentiation, and transformationQ35770614
14-3-3 proteins: a number of functions for a numbered proteinQ35841994
FoxO proteins in insulin action and metabolismQ36110215
FoxO1 integrates insulin signaling to VLDL productionQ37148966
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolismQ37149810
Overindulgence and metabolic syndrome: is FoxO1 a missing link?Q38572199
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectgluconeogenesisQ191835
preproinsulinQ7240673
P304page(s)2763-2774
P577publication date2011-09-22
P1433published inDiabetesQ895262
P1476titleFoxO6 integrates insulin signaling with gluconeogenesis in the liver
P478volume60

Reverse relations

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Q51128779Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter.
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