Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b.

scientific article

Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PNAS..10817408R
P356DOI10.1073/PNAS.1112660108
P932PMC publication ID3198317
P698PubMed publication ID21969554
P5875ResearchGate publication ID51691215

P50authorDaniel R SchoenbergQ47102298
Murugesan V S RajaramQ79287506
Baskar BakthavachaluQ83490909
Jordi B TorrellesQ89438944
P2093author name stringLarry S Schlesinger
Michelle N Brooks
Bin Ni
Jessica D Morris
Tracy K Carlson
P2860cites workMiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine responseQ21142683
AU binding proteins recruit the exosome to degrade ARE-containing mRNAsQ24291926
Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAsQ24292131
Inositol phosphatase SHIP1 is a primary target of miR-155Q24648984
Involvement of microRNA in AU-rich element-mediated mRNA instabilityQ28118466
Lipomannans, but not lipoarabinomannans, purified from Mycobacterium chelonae and Mycobacterium kansasii induce TNF-alpha and IL-8 secretion by a CD14-toll-like receptor 2-dependent mechanismQ28155906
Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannanQ28235685
IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland developmentQ28508430
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levelsQ28586348
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesisQ28593865
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alphaQ28594475
Nuclear localization of p38 MAPK in response to DNA damageQ28646177
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shockQ29619768
Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in miceQ29622922
Acylation state of the phosphatidylinositol hexamannosides from Mycobacterium bovis bacillus Calmette Guerin and mycobacterium tuberculosis H37Rv and its implication in Toll-like receptor responseQ30939823
Diversity in Mycobacterium tuberculosis mannosylated cell wall determinants impacts adaptation to the hostQ33794104
Estradiol suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophagesQ33902210
Mechanisms regulating the nuclear translocation of p38 MAP kinaseQ34117668
Mycobacterium tuberculosis activates human macrophage peroxisome proliferator-activated receptor gamma linking mannose receptor recognition to regulation of immune responsesQ34459867
Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver diseaseQ34489050
Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich elementQ34519852
Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune responseQ34649660
Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory responseQ34995320
Macrophage signalling upon mycobacterial infection: the MAP kinases lead the way.Q35076743
Structural differences in lipomannans from pathogenic and nonpathogenic mycobacteria that impact CD1b-restricted T cell responsesQ35371508
Immunological control of tuberculosis: role of tumour necrosis factor and moreQ36292624
MAPKAP kinases - MKs - two's company, three's a crowdQ36371939
microRNAs and the immune responseQ37178538
MAPK-activated protein kinase 2 differentially regulates plasmodium falciparum glycosylphosphatidylinositol-induced production of tumor necrosis factor-{alpha} and interleukin-12 in macrophagesQ37257347
Physiological and pathological roles for microRNAs in the immune systemQ37680666
Increased mitogen-activated protein kinase activity and TNF-alpha production associated with Mycobacterium smegmatis- but not Mycobacterium avium-infected macrophages requires prolonged stimulation of the calmodulin/calmodulin kinase and cyclic AMP/Q39609903
Reduced transcript stabilization restricts TNF-alpha expression in RAW264.7 macrophages infected with pathogenic mycobacteria: evidence for an involvement of lipomannanQ39784378
Mannan chain length controls lipoglycans signaling via and binding to TLR2.Q39985815
Differential regulation of ARE-mediated TNFalpha and IL-1beta mRNA stability by lipopolysaccharide in RAW264.7 cellsQ40270492
Approaches for studying PMR1 endonuclease-mediated mRNA decayQ41817581
Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways.Q43241254
Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infectionQ43612818
Leptin-induced cardiomyocyte hypertrophy involves selective caveolae and RhoA/ROCK-dependent p38 MAPK translocation to nucleiQ46897866
Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannansQ47914814
Secretion of cytokines by human macrophages upon infection by pathogenic and non-pathogenic mycobacteriaQ58076863
The essential role of the UA-rich sequence in endotoxin-induced cachectin/TNF synthesisQ68080676
Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complexQ69824731
Macrophage phagocytosis of virulent but not attenuated strains of Mycobacterium tuberculosis is mediated by mannose receptors in addition to complement receptorsQ70615398
P433issue42
P407language of work or nameEnglishQ1860
P921main subjectTNFQ18032037
Mycobacterium tuberculosisQ130971
macrophageQ184204
microRNAQ310899
P1104number of pages6
P304page(s)17408-17413
P577publication date2011-10-03
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b
P478volume108

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