IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

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IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0092-8674(01)00599-2
P3181OpenCitations bibliographic resource ID2350168
P698PubMed publication ID11747812

P50authorFlorian GretenQ17321656
Tiffany N SeagrovesQ73088022
P2093author name stringM. Karin
R. Johnson
Y. Cao
E. V. Schmidt
G. Bonizzi
P2860cites workB cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50Q24316476
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IKKalpha controls formation of the epidermis independently of NF-kappaB.Q42502421
IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosisQ46607308
Mammary glands of Aly mice: developmental changes and lactation-related expression of specific proteins, alpha-casein, GLyCAM-1 and MAdCAM-1.Q52166546
Genetics of RAS signaling in C. elegans.Q52182134
Cyclin D1 provides a link between development and oncogenesis in the retina and breastQ52206604
Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.Q52542561
Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.Q53461014
Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3Q73540287
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activationQ24321727
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaBQ24321775
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIKQ24321797
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradationQ24650561
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responsesQ27861101
Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylationQ28140878
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland developmentQ28142247
Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulationQ28208562
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathwayQ28214369
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activationQ28252726
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.Q33959017
Specific protection against breast cancers by cyclin D1 ablationQ34082446
The I kappa B kinase: a master regulator of NF-kappa B, innate immunity, and epidermal differentiation.Q34170916
Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regionsQ34295503
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic miceQ34342812
Signaling pathways in mammary gland development.Q34434909
C/EBPbeta, but not C/EBPalpha, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland.Q35202739
An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosisQ35834615
Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epitheliumQ36283770
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosisQ36368249
Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitectureQ36400143
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responsesQ36400158
Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growthQ36569036
Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancerQ37376029
NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transitionQ39445143
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cellsQ39795545
The Ras signaling pathway in DrosophilaQ40525097
NF-kappaB inhibits apoptosis in murine mammary epitheliaQ40884614
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinaseQ40954925
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient miceQ40956523
Severe liver degeneration in mice lacking the IkappaB kinase 2 geneQ40962152
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinaseQ41644582
IkappaB kinase alpha is essential for mature B cell development and functionQ42175977
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectCyclin D1Q15311866
Inhibitor of nuclear factor kappa-B kinase subunit alphaQ21495135
P304page(s)763–775
P577publication date2001-12-14
P1433published inCellQ655814
P1476titleIKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development
P478volume107

Reverse relations

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