scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Kate L Weeks | Q54139861 |
Metin Avkiran | Q30169436 | ||
P2093 | author name string | Kate L Weeks | |
Metin Avkiran | |||
P2860 | cites work | Three proteins define a class of human histone deacetylases related to yeast Hda1p | Q22009464 |
Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5 | Q22011186 | ||
Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor | Q22253464 | ||
Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization | Q22254367 | ||
Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation | Q24290523 | ||
Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5 | Q24290618 | ||
Cloning and characterization of a histone deacetylase, HDAC9 | Q24291641 | ||
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR | Q24292197 | ||
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy | Q24293269 | ||
PP2A regulates HDAC4 nuclear import | Q24301735 | ||
New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases | Q24303533 | ||
An expression screen reveals modulators of class II histone deacetylase phosphorylation | Q24304114 | ||
AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5 | Q24306179 | ||
Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation | Q24307379 | ||
Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis | Q24309609 | ||
Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications | Q24324035 | ||
Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats. | Q43140361 | ||
Agonist-induced nuclear export of GFP-HDAC5 in isolated adult rat ventricular myocytes | Q45851266 | ||
Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1. | Q46026253 | ||
Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding | Q46870302 | ||
Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. | Q47860803 | ||
Neurohormonal regulation of cardiac histone deacetylase 5 nuclear localization by phosphorylation-dependent and phosphorylation-independent mechanisms. | Q53169145 | ||
Valproate attenuates the risk of myocardial infarction in patients with epilepsy: a nationwide cohort study | Q57260389 | ||
Inhibition of histone deacetylase on ventricular remodeling in infarcted rats | Q80076073 | ||
Treatment of chronic heart failure with β-adrenergic receptor antagonists: a convergence of receptor pharmacology and clinical cardiology | Q82242423 | ||
Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis | Q40568219 | ||
The CRM1 nuclear export receptor controls pathological cardiac gene expression | Q40586178 | ||
HDAC inhibition suppresses cardiac hypertrophy and fibrosis in DOCA-salt hypertensive rats via regulation of HDAC6/HDAC8 enzyme activity | Q41166649 | ||
Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy | Q41836714 | ||
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling | Q41919774 | ||
HDAC4 controls histone methylation in response to elevated cardiac load | Q41992090 | ||
BET acetyl-lysine binding proteins control pathological cardiac hypertrophy | Q42709887 | ||
Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure | Q42928039 | ||
Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice | Q43012174 | ||
Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors | Q24519076 | ||
HDAC4 deacetylase associates with and represses the MEF2 transcription factor | Q24534407 | ||
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase | Q24534918 | ||
Histone deacetylases (HDACs): characterization of the classical HDAC family | Q24535587 | ||
Identification of a signal-responsive nuclear export sequence in class II histone deacetylases | Q24550848 | ||
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5 | Q24561772 | ||
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression | Q24610596 | ||
Epigenetic control of skull morphogenesis by histone deacetylase 8 | Q24646214 | ||
Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice | Q24650710 | ||
Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers | Q24673210 | ||
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases | Q24682791 | ||
Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop | Q24682945 | ||
Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly | Q27666773 | ||
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure | Q27865207 | ||
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases | Q27934108 | ||
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy | Q28219383 | ||
Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family | Q28252866 | ||
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy | Q28269300 | ||
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy | Q28504909 | ||
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis | Q28505748 | ||
SUMO1-dependent modulation of SERCA2a in heart failure | Q28508610 | ||
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity | Q28508698 | ||
Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10 | Q28509194 | ||
The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis | Q28513025 | ||
Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy | Q28573635 | ||
SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes | Q28590015 | ||
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development | Q28592216 | ||
Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4 | Q28592681 | ||
Chemical phylogenetics of histone deacetylases | Q30977637 | ||
Isoform-selective HDAC inhibitors: Closing in on translational medicine for the heart | Q33392979 | ||
Nuclear Import of Histone Deacetylase 5 by Requisite Nuclear Localization Signal Phosphorylation | Q33748395 | ||
Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats | Q33772867 | ||
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling | Q33913127 | ||
Targeted deletion of NF-kappaB p50 diminishes the cardioprotection of histone deacetylase inhibition | Q33917016 | ||
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy | Q33929939 | ||
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression | Q34088777 | ||
HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats | Q34099442 | ||
PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy | Q34100575 | ||
Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling | Q34217961 | ||
Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy. | Q34319871 | ||
BET bromodomains mediate transcriptional pause release in heart failure | Q34361491 | ||
Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure | Q35228115 | ||
Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin | Q35312534 | ||
Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4. | Q35503840 | ||
Back to your heart: ubiquitin proteasome system-regulated signal transduction | Q35803035 | ||
Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesis | Q35847709 | ||
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility | Q35893654 | ||
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases | Q36141408 | ||
Requirement of protein kinase D1 for pathological cardiac remodeling | Q36498485 | ||
Acute β-adrenergic activation triggers nuclear import of histone deacetylase 5 and delays G(q)-induced transcriptional activation | Q36508570 | ||
Cardiac hypertrophy induced by sustained beta-adrenoreceptor activation: pathophysiological aspects. | Q36771475 | ||
HDAC-dependent ventricular remodeling | Q36945016 | ||
Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia | Q37095364 | ||
The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload | Q37114848 | ||
Defective sumoylation pathway directs congenital heart disease | Q37273083 | ||
Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300. | Q37303806 | ||
VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis | Q37353597 | ||
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. | Q37700043 | ||
Inside HDAC with HDAC inhibitors | Q37707623 | ||
Therapeutic potential for HDAC inhibitors in the heart | Q37937667 | ||
The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases | Q39197659 | ||
Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases | Q39214537 | ||
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure | Q39951451 | ||
Dephosphorylation and caspase processing generate distinct nuclear pools of histone deacetylase 4. | Q40106235 | ||
Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation | Q40435172 | ||
Caspase-mediated specific cleavage of human histone deacetylase 4. | Q40543725 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | regulation of gene expression | Q411391 |
isoform | Q609809 | ||
human musculoskeletal system | Q726543 | ||
cell | Q7868 | ||
post-translational protein modification | Q898362 | ||
cardiomegaly | Q1729124 | ||
tissue | Q40397 | ||
enzyme | Q8047 | ||
circulatory system | Q11068 | ||
P304 | page(s) | 1785-1797 | |
P577 | publication date | 2014-11-25 | |
2015-04-15 | |||
P1433 | published in | Journal of Physiology | Q7743612 |
P1476 | title | Roles and post-translational regulation of cardiac class IIa histone deacetylase isoforms | |
P478 | volume | 593 |
Q37218059 | A class of their own: exploring the nondeacetylase roles of class IIa HDACs in cardiovascular disease |
Q47567230 | A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway. |
Q53182665 | Activating transcription factor 3 SUMOylation is involved in angiotensin II-induced endothelial cell inflammation and dysfunction. |
Q52689351 | Bidirectional regulation of HDAC5 by mAKAPβ signalosomes in cardiac myocytes. |
Q88453278 | Epigenetics of Aberrant Cardiac Wound Healing |
Q64261117 | HDAC inhibitors and cardioprotection: Homing in on a mechanism of action |
Q93056448 | Histone deacetylases in cardiovascular and metabolic diseases |
Q38974621 | How cardiomyocytes sense pathophysiological stresses for cardiac remodeling. |
Q55625734 | Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2-dependent transcription in cardiac myocytes. |
Q39034552 | MicroRNA-1 overexpression blunts cardiomyocyte hypertrophy elicited by thyroid hormone. |
Q90290390 | Novel Insight Into the Epigenetic and Post-transcriptional Control of Cardiac Gene Expression by Thyroid Hormone |
Q90627698 | Nucleoporins in cardiovascular disease |
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Q50233552 | Serine/Threonine Kinase 40 (Stk40) Functions as a Novel Regulator of Skeletal Muscle Differentiation |
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Q49917356 | Understanding Key Mechanisms of Exercise-Induced Cardiac Protection to Mitigate Disease: Current Knowledge and Emerging Concepts |
Q41165926 | β-Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α-PP2A-Mediated Dephosphorylation. |
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