Histone deacetylases in cardiovascular and metabolic diseases

scientific article published on 09 April 2019

Histone deacetylases in cardiovascular and metabolic diseases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YJMCC.2019.04.003
P698PubMed publication ID30978343

P2093author name stringKate L Weeks
Rushita A Bagchi
P2860cites workHDAC inhibition helps post-MI healing by modulating macrophage polarization.Q52717737
HDAC11 deletion reduces fructose-induced cardiac dyslipidemia, apoptosis and inflammation by attenuating oxidative stress injury.Q52719352
Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.Q52793543
Novel Histone Deacetylase Inhibitor Modulates Cardiac Peroxisome Proliferator-Activated Receptors and Inflammatory Cytokines in Heart Failure.Q55044891
Histone Deacetylase 11 Is an ε-N-Myristoyllysine HydrolaseQ57175323
Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular DiseasesQ57822214
HDAC11 suppresses the thermogenic program of adipose tissue via BRD2Q58792327
Effect of recombinant human insulin-like growth factor-I on expression of glucose transporters, GLUT 2 and GLUT 4, in streptozotocin-diabetic ratQ77518604
Inhibition of histone deacetylase on ventricular remodeling in infarcted ratsQ80076073
HDAC6 Promotes Cardiac Fibrosis Progression through Suppressing RASSF1A ExpressionQ86246870
Maternal high fat diet induces early cardiac hypertrophy and alters cardiac metabolism in Sprague Dawley rat offspringQ88461337
Programming and Regulation of Metabolic Homeostasis by HDAC11Q89353095
Three proteins define a class of human histone deacetylases related to yeast Hda1pQ22009464
Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressorQ22253464
Histone deacetylases specifically down-regulate p53-dependent gene activationQ22253949
Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localizationQ22254367
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoRQ24292197
Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domainQ24292353
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophyQ24293269
HDAC6 is a microtubule-associated deacetylaseQ24298013
AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5Q24306179
Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiationQ24307379
HDAC4 deacetylase associates with and represses the MEF2 transcription factorQ24534407
Histone deacetylases (HDACs): characterization of the classical HDAC familyQ24535587
Identification of a signal-responsive nuclear export sequence in class II histone deacetylasesQ24550848
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5Q24561772
Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3Q24648290
Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in miceQ24650710
Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2Q24673733
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylasesQ24682791
Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein HopQ24682945
Lysine acetylation targets protein complexes and co-regulates major cellular functionsQ27860589
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failureQ27865207
Glucose Transporters in Cardiac Metabolism and HypertrophyQ28075863
Deacetylation of p53 modulates its effect on cell growth and apoptosisQ28138967
Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70Q28214548
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophyQ28219383
Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene familyQ28252866
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3pQ28276243
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activityQ28508698
Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10Q28509194
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart developmentQ28592216
Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4Q28592681
Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart StudyQ29614968
EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent.Q33591193
Histone deacetylase inhibitor treatment increases coronary t-PA release in a porcine ischemia modelQ33599573
Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusionQ33714350
Histone deacetylase 10 structure and molecular function as a polyamine deacetylaseQ33753801
HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activationQ33891516
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signalingQ33913127
Targeted deletion of NF-kappaB p50 diminishes the cardioprotection of histone deacetylase inhibitionQ33917016
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophyQ33929939
Left ventricular hypertrophy: pathogenesis, detection, and prognosisQ33977917
Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytesQ33998649
Controlling the double helixQ34172152
Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).Q34206633
Class II histone deacetylases limit GLUT4 gene expression during adipocyte differentiationQ34452611
Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid OxidationQ34540285
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5Q34761571
Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammationQ34788395
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertensionQ35040811
Histone deacetylase 9 is a negative regulator of adipogenic differentiationQ35145068
Inhibition of HDAC3 promotes ligand-independent PPARγ activation by protein acetylationQ35338684
Roles and post-translational regulation of cardiac class IIa histone deacetylase isoforms.Q35517710
Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarctionQ35671740
Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesisQ35847709
Histone Deacetylase 3 (HDAC3)-dependent Reversible Lysine Acetylation of Cardiac Myosin Heavy Chain Isoforms Modulates Their Enzymatic and Motor ActivityQ35860651
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractilityQ35893654
Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic miceQ35922922
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylasesQ36141408
Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse DevelopmentQ36481113
Histone deacetylase inhibitor, CG200745, attenuates cardiac hypertrophy and fibrosis in DOCA-induced hypertensive ratsQ37239770
HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feedingQ37403326
Investigating the selectivity of metalloenzyme inhibitorsQ37432771
Molecular mechanisms of diabetic cardiomyopathy.Q37672583
Erasers of histone acetylation: the histone deacetylase enzymesQ37673993
Myocardial fatty acid metabolism in health and diseaseQ37677921
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy.Q37700043
The worldwide epidemiology of type 2 diabetes mellitus--present and future perspectivesQ37953791
Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs.Q38196176
Inflammation as a link between obesity, metabolic syndrome and type 2 diabetesQ38209594
Global and regional patterns in cardiovascular mortality from 1990 to 2013.Q38616787
Multi-Cellular Transcriptional Analysis of Mammalian Heart RegenerationQ38667300
Inflammatory processes in cardiovascular disease: a route to targeted therapiesQ38788685
Scriptaid enhances skeletal muscle insulin action and cardiac function in obese miceQ38982581
Histone deacetylase 5 regulates glucose uptake and insulin action in muscle cellsQ39275916
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failureQ39951451
The CRM1 nuclear export receptor controls pathological cardiac gene expressionQ40586178
Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial FibrillationQ41150386
β-Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α-PP2A-Mediated Dephosphorylation.Q41165926
Regulation of cardiac stress signaling by protein kinase d1.Q41496270
Diabetes and cardiovascular disease. The Framingham studyQ41509493
miR-21-3p regulates cardiac hypertrophic response by targeting histone deacetylase-8.Q41693992
GLUT4 enhancer factor (GEF) interacts with MEF2A and HDAC5 to regulate the GLUT4 promoter in adipocytesQ41908985
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription couplingQ41919774
HDAC4 controls histone methylation in response to elevated cardiac loadQ41992090
Maintenance of cardiac energy metabolism by histone deacetylase 3 in miceQ43012174
Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats.Q43140361
Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failureQ43523644
Exercise and myocyte enhancer factor 2 regulation in human skeletal muscleQ44865473
Activation of histone deacetylase-6 induces contractile dysfunction through derailment of α-tubulin proteostasis in experimental and human atrial fibrillation.Q45997206
Sodium Butyrate Protects -Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic MiceQ46429786
The use of diversity profiling to characterize chemical modulators of the histone deacetylasesQ46613064
Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic bandingQ46870302
A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.Q47567230
Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. Regulation of MEF2 DNA binding activity in insulin-deficient diabetesQ48034669
Histone Deacetylase 11 Is a Fatty-Acid DeacylaseQ48237457
Implications of Underlying Mechanisms for the Recognition and Management of Diabetic CardiomyopathyQ49955216
Diabetic Cardiomyopathy: An Update of Mechanisms Contributing to This Clinical EntityQ49960457
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.Q50045909
P304page(s)151-159
P577publication date2019-04-09
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleHistone deacetylases in cardiovascular and metabolic diseases
P478volume130

Reverse relations

cites work (P2860)
Q99708050CaMKII exacerbates heart failure progression by activating class I HDACs
Q92730996Pathogenic implications of dysregulated miRNAs in propionic acidemia related cardiomyopathy
Q92344377The Anti-Fibrotic Effects of CG-745, an HDAC Inhibitor, in Bleomycin and PHMG-Induced Mouse Models
Q91646371The Epac1 Protein: Pharmacological Modulators, Cardiac Signalosome and Pathophysiology

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