Increased Expression of the Large Conductance, Calcium-Activated K+ (BK) Channel in Adult-Onset Neuronal Ceroid Lipofuscinosis

scientific article published on 23 April 2015

Increased Expression of the Large Conductance, Calcium-Activated K+ (BK) Channel in Adult-Onset Neuronal Ceroid Lipofuscinosis is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1025205D
P356DOI10.1371/JOURNAL.PONE.0125205
P932PMC publication ID4407904
P698PubMed publication ID25905915
P5875ResearchGate publication ID275358726

P2093author name stringJanice E A Braun
Milen Velinov
Eva Ahrendt
Andrew P Braun
Julien Donnelier
Natalia Dolzhanskaya
Samuel T Braun
P2860cites workExome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosisQ21090977
J protein mutations and resulting proteostasis collapseQ21129474
Quercetin targets cysteine string protein (CSPalpha) and impairs synaptic transmissionQ21562195
Mutations in DNAJC5, encoding cysteine-string protein alpha, cause autosomal-dominant adult-onset neuronal ceroid lipofuscinosisQ24319132
CSPα knockout causes neurodegeneration by impairing SNAP-25 functionQ26269887
Rab-alphaGDI activity is regulated by a Hsp90 chaperone complexQ28578339
Oligomerization characteristics of cysteine string proteinQ28580744
Alpha-synuclein cooperates with CSPalpha in preventing neurodegenerationQ28587785
The HSP70 chaperone machinery: J proteins as drivers of functional specificityQ29616140
Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.Q30594778
The regulation of BK channel activity by pre- and post-translational modificationsQ34077885
Phosphorylation of cysteine string protein by protein kinase A. Implications for the modulation of exocytosisQ34095436
Mutations in the gene DNAJC5 cause autosomal dominant Kufs disease in a proportion of cases: study of the Parry family and 8 other familiesQ34123856
A charged prominence in the linker domain of the cysteine-string protein Cspα mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosisQ34138424
Oligomerization of Cysteine String Protein alpha mutants causing adult neuronal ceroid lipofuscinosisQ34302115
The synaptic vesicle protein CSP alpha prevents presynaptic degeneration.Q34314406
Extensive lipidation of a Torpedo cysteine string protein.Q34330430
Characterization of the G alpha(s) regulator cysteine string proteinQ34428333
Identification of CSPα clients reveals a role in dynamin 1 regulation.Q35893528
Motorneurons require cysteine string protein-α to maintain the readily releasable vesicular pool and synaptic vesicle recycling.Q50499095
Overexpression of cysteine-string proteins in Drosophila reveals interactions with syntaxin.Q52574622
CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.Q54397791
Case 8-2011Q60800665
Interaction of cysteine string proteins with the alpha1A subunit of the P/Q-type calcium channelQ74567363
Two distinct domains in hsc70 are essential for the interaction with the synaptic vesicle cysteine string proteinQ78074534
Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosisQ36347832
Biological roles of neural J proteinsQ37148343
DNAJ proteins and protein aggregation diseases.Q38075883
CSPα-chaperoning presynaptic proteinsQ38210203
Cysteine string protein functions directly in regulated exocytosisQ38612674
Cysteine string protein limits expression of the large conductance, calcium-activated K⁺ (BK) channelQ39029381
Crosstalk between huntingtin and syntaxin 1A regulates N-type calcium channels.Q40373593
Cysteine string protein regulates G protein modulation of N-type calcium channelsQ40841138
Phosphorylation-dependent interaction of the synaptic vesicle proteins cysteine string protein and synaptotagmin I.Q42123208
Activation of the ATPase activity of heat-shock proteins Hsc70/Hsp70 by cysteine-string proteinQ42216617
The large conductance, calcium-activated K+ (BK) channel is regulated by cysteine string proteinQ42555501
Cysteine string protein-alpha prevents activity-dependent degeneration in GABAergic synapses.Q43053624
Molecular determinants of cysteine string protein modulation of N-type calcium channelsQ44463991
The cysteine string secretory vesicle protein activates Hsc70 ATPaseQ46053336
Paralysis and early death in cysteine string protein mutants of DrosophilaQ46085105
Cysteine string protein, a DnaJ family member, is present on diverse secretory vesiclesQ48069405
Proteasome inhibition alleviates SNARE-dependent neurodegenerationQ48407910
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectneuronal ceroid lipofuscinosisQ4358039
P304page(s)e0125205
P577publication date2015-04-23
P1433published inPLOS OneQ564954
P1476titleIncreased Expression of the Large Conductance, Calcium-Activated K+ (BK) Channel in Adult-Onset Neuronal Ceroid Lipofuscinosis
P478volume10

Reverse relations

cites work (P2860)
Q30356551BK Channels in the Central Nervous System.
Q36321613Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss
Q51246997Early Alterations of Hippocampal Neuronal Firing Induced by Abeta42.
Q42269174Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo
Q42490346Presynaptic BK channels control transmitter release: physiological relevance and potential therapeutic implications.
Q38663518Primary fibroblasts from CSPα mutation carriers recapitulate hallmarks of the adult onset neuronal ceroid lipofuscinosis

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