Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias.

scientific article published on 10 May 2014

Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YJMCC.2014.04.024
P932PMC publication ID4412372
P698PubMed publication ID24819345

P50authorGene KimQ55153249
P2093author name stringTyler Calway
Michael Broman
Judy Earley
Appledene Osbourne
Saoirse McSharry
P2860cites workAccurate microRNA target prediction correlates with protein repression levelsQ21284375
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BIN1 localizes the L-type calcium channel to cardiac T-tubulesQ27324852
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The functions of animal microRNAsQ27860621
Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia.Q52524238
Remodeling of gap junctional channel function in epicardial border zone of healing canine infarctsQ73035933
Disparate effects of deficient expression of connexin43 on atrial and ventricular conduction: evidence for chamber-specific molecular determinants of conductionQ74292476
Reentry and fibrillation in the mouse heart. A challenge to the critical mass hypothesisQ78031811
Fibrosis of collagen I and remodeling of connexin 43 in atrial myocardium of patients with atrial fibrillationQ80213563
Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophyQ84391956
MicroRNA-130a mediates proliferation of vascular smooth muscle cells in hypertensionQ84554499
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissueQ28116497
Embryonic stem cell-specific MicroRNAsQ28201906
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Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43Q28506915
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Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmiasQ30501712
Connexins and the atrioventricular nodeQ30535769
Translational control of FOG-2 expression in cardiomyocytes by microRNA-130aQ33479126
MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complexQ34097829
Structural and functional diversity of connexin genes in the mouse and human genomeQ34137753
Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and functionQ34154702
CYP2J2 overexpression protects against arrhythmia susceptibility in cardiac hypertrophyQ34983743
MicroRNA-130a represses transcriptional activity of aquaporin 4 M1 promoterQ35874426
Biological role of connexin intercellular channels and hemichannelsQ36035603
Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesisQ36710861
Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation.Q36788875
Remodelling of gap junctions and connexin expression in diseased myocardium.Q36870641
Arrhythmia and sudden death associated with elevated cardiac chloride channel activityQ37294837
Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization.Q37315854
Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support.Q37358790
Focal gap junction uncoupling and spontaneous ventricular ectopy.Q37374412
Connexin43 cardiac gap junction remodeling: lessons from genetically engineered murine modelsQ38020754
MicroRNA regulation of cardiac conduction and arrhythmiasQ38070298
Connexin gene transfer preserves conduction velocity and prevents atrial fibrillation.Q38435600
The hepatitis B virus-associated estrogen receptor alpha (ERalpha) was regulated by microRNA-130a in HepG2.2.15 human hepatocellular carcinoma cellsQ39516485
MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillationQ40036365
MicroRNA- 1 represses Cx43 expression in viral myocarditisQ40036400
Gap junction protein phenotypes of the human heart and conduction systemQ40970873
Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoterQ44353726
Subdiaphragmatic murine electrophysiological studies: sequential determination of ventricular refractoriness and arrhythmia inductionQ44443099
Detection of microRNAs in frozen tissue sections by fluorescence in situ hybridization using locked nucleic acid probes and tyramide signal amplificationQ46941943
Loss of angiomiR-126 and 130a in angiogenic early outgrowth cells from patients with chronic heart failure: role for impaired in vivo neovascularization and cardiac repair capacityQ47037320
Influence of electrical coupling on early afterdepolarizations in ventricular myocytes.Q52225020
P4510describes a project that usesImageJQ1659584
P921main subjectmicroRNAQ310899
P304page(s)53-63
P577publication date2014-05-10
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleDownregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias
P478volume74