A dPIP5K dependent pool of phosphatidylinositol 4,5 bisphosphate (PIP2) is required for G-protein coupled signal transduction in Drosophila photoreceptors

scientific article published on 29 January 2015

A dPIP5K dependent pool of phosphatidylinositol 4,5 bisphosphate (PIP2) is required for G-protein coupled signal transduction in Drosophila photoreceptors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1004948
P932PMC publication ID4310717
P698PubMed publication ID25633995
P5875ResearchGate publication ID271593872

P50authorShweta YadavQ85643461
Sourav KolayQ86624231
Deepti TrivediQ41840486
P2093author name stringPurbani Chakrabarti
Amit Nair
Padinjat Raghu
Kamalesh Kumari
P2860cites workType I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase familyQ24336406
Evidence that inositol 1-phosphate in brain of lithium-treated rats results mainly from phosphatidylinositol metabolismQ24529399
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptorsQ24671705
The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiaeQ27939343
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identityQ28118990
PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapseQ28198985
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talinQ28214335
Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesionsQ28214350
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphateQ28254402
A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gammaQ28508645
Alpha1-adrenergic receptor signaling is localized to caveolae in neonatal rat cardiomyocytesQ28573225
Analysis of genetic mosaics in developing and adult Drosophila tissuesQ29617838
Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.Q30479032
Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motorQ30493987
Phosphatidylinositol 4,5-bisphosphate directs spermatid cell polarity and exocyst localization in Drosophila.Q30494269
Regulation of cortical structure by the ezrin-radixin-moesin protein familyQ33536481
Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnoverQ34067259
Visual transduction in Drosophila.Q34091337
Lipid signaling in Drosophila photoreceptorsQ34266878
The complex and intriguing lives of PIP2 with ion channels and transportersQ34457658
ERM proteins in epithelial cell organization and functionsQ34556675
P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster.Q34586256
The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration.Q52584172
A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila.Q52584174
Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors.Q52588091
The activation loop of phosphatidylinositol phosphate kinases determines signaling specificityQ73456411
Stereo-specific substrate recognition by phosphatidylinositol phosphate kinases is swapped by changing a single amino acid residueQ77322068
skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter releaseQ34605918
A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype.Q34607330
Ends-out, or replacement, gene targeting in DrosophilaQ34807177
Targeted mutagenesis by homologous recombination in D. melanogasterQ35778193
Light-induced recruitment of INAD-signaling complexes to detergent-resistant lipid rafts in Drosophila photoreceptorsQ36082813
Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide poolsQ36255578
Mutations in phosphoinositide metabolizing enzymes and human diseaseQ36402106
Hereditary retinal degeneration in Drosophila melanogaster. A mutant defect associated with the phototransduction processQ36407688
Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalphaQ36438800
Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila developmentQ36762659
RdgB proteins: functions in lipid homeostasis and signal transductionQ36837571
Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formationQ36893688
Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.Q37237866
Regulation of Drosophila TRPC channels by lipid messengersQ37442159
How actin gets the PIP.Q37989136
Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis.Q40704860
Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cellsQ41056247
Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slicesQ42008702
Quantitative tissue isolation from Drosophila freeze-dried in acetoneQ42022444
The gene search system. A method for efficient detection and rapid molecular identification of genes in Drosophila melanogasterQ42563989
Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo.Q42814440
Multiple metabolic pools of phosphoinositides and phosphatidate in human erythrocytes incubated in a medium that permits rapid transmembrane exchange of phosphateQ42856053
Moesin contributes an essential structural role in Drosophila photoreceptor morphogenesisQ44728565
Functional INAD complexes are required to mediate degeneration in photoreceptors of the Drosophila rdgA mutantQ45310672
Loss of the phospholipase C gene product induces massive endocytosis of rhodopsin and arrestin in Drosophila photoreceptorsQ45712563
Gqα protein function in vivo: Genetic dissection of its role in photoreceptor cell physiologyQ45980451
Rab11 mediates post-Golgi trafficking of rhodopsin to the photosensitive apical membrane of Drosophila photoreceptorsQ47070686
Rescue of photoreceptor degeneration in rhodopsin-null Drosophila mutants by activated Rac1.Q47070814
PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte.Q47070817
PIPkins1, their substrates and their products: new functions for old enzymesQ48566438
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue1
P921main subjectG protein-coupled receptorQ38173
DrosophilaQ312154
photoreceptor proteinQ7187894
Retinal degeneration B Dmel_CG11111Q29816015
P304page(s)e1004948
P577publication date2015-01-29
P1433published inPLOS GeneticsQ1893441
P1476titleA dPIP5K dependent pool of phosphatidylinositol 4,5 bisphosphate (PIP2) is required for G-protein coupled signal transduction in Drosophila photoreceptors
P478volume11

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cites work (P2860)
Q90475641A PI4KIIIα protein complex is required for cell viability during Drosophila wing development
Q38861831Control of diverse subcellular processes by a single multi-functional lipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2].
Q54119901Genetic dissection of the phosphoinositide cycle in Drosophila photoreceptors.
Q93070830Immunocytochemical Labeling of Rhabdomeric Proteins in Drosophila Photoreceptor Cells Is Compromised by a Light-dependent Technical Artifact
Q36462486In vivo tracking of phosphoinositides in Drosophila photoreceptors.
Q91198636Interplay between integrins and PI4P5K Sktl is crucial for cell polarization and reepithelialisation during Drosophila wound healing
Q64065338PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation
Q41189491Phosphatidylinositol 5-phosphate 4-kinase regulates early endosomal dynamics during clathrin-mediated endocytosis.
Q47988436Phosphoinositides and Cell Polarity in the Drosophila Egg Chamber
Q90049726Phosphoinositides: Regulators of Nervous System Function in Health and Disease
Q36091128RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction
Q89449352Regulation of PI4P levels by PI4KIIIα during G-protein-coupled PLC signaling in Drosophila photoreceptors

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