Phosphatidylinositol 5-phosphate 4-kinase regulates early endosomal dynamics during clathrin-mediated endocytosis.

scientific article published on 15 May 2017

Phosphatidylinositol 5-phosphate 4-kinase regulates early endosomal dynamics during clathrin-mediated endocytosis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/JCS.202259
P932PMC publication ID5536888
P698PubMed publication ID28507272

P50authorDeepti TrivediQ41840486
Sourav KolayQ86624231
Padinjat RaghuQ87747602
Kumari KamaleshQ88069899
Sarah ToscanoQ88069900
Sanjeev SharmaQ88069901
P2093author name stringSanjeev Sharma
Sarah Toscano
Deepti Trivedi
Padinjat Raghu
Kumari Kamalesh
Sourav Kolay
P2860cites workAccumulation of rhodopsin in late endosomes triggers photoreceptor cell degenerationQ21145009
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EEA1 links PI(3)K function to Rab5 regulation of endosome fusionQ24322668
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The endocytic recycling compartment maintains cargo segregation acquired upon exit from the sorting endosomeQ27305230
The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degenerationQ27315072
Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiaeQ27939346
The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminalsQ28118433
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphateQ28254402
Rab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cellsQ28509305
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosisQ29618143
Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.Q30479032
Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and sizeQ30502441
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathwayQ31105211
Analysis of endocytic pathways in Drosophila cells reveals a conserved role for GBF1 in internalization via GEECsQ33496745
Regulation of mTORC1 by the Rab and Arf GTPasesQ33924196
Visual transduction in Drosophila.Q34091337
Lipid signaling in Drosophila photoreceptorsQ34266878
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle traffickingQ34350922
Arrestin1 mediates light-dependent rhodopsin endocytosis and cell survivalQ34458080
Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4KbetaQ34562857
A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cellsQ35173167
A dPIP5K dependent pool of phosphatidylinositol 4,5 bisphosphate (PIP2) is required for G-protein coupled signal transduction in Drosophila photoreceptorsQ35551486
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Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila PhotoreceptorsQ35927400
Rab5 proteins regulate activation and localization of target of rapamycin complex 1.Q36033140
Myosin V, Rab11, and dRip11 direct apical secretion and cellular morphogenesis in developing Drosophila photoreceptorsQ36118325
EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cellsQ36274523
deep-orange and carnation define distinct stages in late endosomal biogenesis in Drosophila melanogasterQ36323472
Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila developmentQ36762659
Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.Q37237866
Overexpression of PPK-1, the Caenorhabditis elegans Type I PIP kinase, inhibits growth cone collapse in the developing nervous system and causes axonal degeneration in adultsQ37275823
Macrophages in Drosophila embryos and L2 cells exhibit scavenger receptor-mediated endocytosisQ37277587
Endosome acidification and receptor trafficking: bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motifQ37376783
Phospholipase D activity couples plasma membrane endocytosis with retromer dependent recycling.Q37446413
Phototransduction motifs and variationsQ37616663
The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin.Q37637412
Defective trafficking of rhodopsin and its role in retinal degenerationsQ37976506
Rhodopsin homeostasis and retinal degeneration: lessons from the fly.Q38135048
Assays to monitor autophagy in DrosophilaQ38199311
Phosphoinositides in membrane contact sitesQ38805776
Different effects of Atg2 and Atg18 mutations on Atg8a and Atg9 trafficking during starvation in Drosophila.Q41965133
Calnexin is essential for rhodopsin maturation, Ca2+ regulation, and photoreceptor cell survivalQ42266704
Prolonged G(q) activity triggers fly rhodopsin endocytosis and degradation, and reduces photoreceptor sensitivityQ42837702
Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling.Q45088123
Gqα protein function in vivo: Genetic dissection of its role in photoreceptor cell physiologyQ45980451
Rab11 mediates post-Golgi trafficking of rhodopsin to the photosensitive apical membrane of Drosophila photoreceptorsQ47070686
The agrin/perlecan-related protein eyes shut is essential for epithelial lumen formation in the Drosophila retinaQ47072271
The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration.Q52584172
A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila.Q52584174
RNA interference of gene expression (RNAi) in cultured Drosophila cells.Q52593075
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectNeither inactivation nor afterpotential E Dmel_CG4550Q29809617
Phosphatidylinositol 5-phosphate 4-kinase Dmel_CG17471Q29813832
P304page(s)2119-2133
P577publication date2017-05-15
P1433published inJournal of Cell ScienceQ1524177
P1476titlePhosphatidylinositol 5-phosphate 4-kinase regulates early endosomal dynamics during clathrin-mediated endocytosis
P478volume130

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cites work (P2860)
Q92111190Defects in COG-Mediated Golgi Trafficking Alter Endo-Lysosomal System in Human Cells
Q95656743Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain
Q63363264Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization
Q64253250Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes
Q64910788Phosphatidylinositol 5 Phosphate 4-Kinase Regulates Plasma-Membrane PIP3 Turnover and Insulin Signaling.
Q90049726Phosphoinositides: Regulators of Nervous System Function in Health and Disease

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