Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes

scientific article published on 19 February 2019

Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BSR20182210
P932PMC publication ID6379509
P698PubMed publication ID30718367

P50authorPadinjat RaghuQ87747602
Avishek GhoshQ91339946
P2093author name stringVisvanathan Ramya
Harini Krishnan
Swarna Mathre
K Balasankara Reddy
P2860cites workEnzyme activity of the PIP4K2A gene product polymorphism that is implicated in schizophreniaQ42910419
Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling.Q45088123
Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.Q46236725
Clustal Omega, accurate alignment of very large numbers of sequences.Q51147183
PI(5)P regulates autophagosome biogenesisQ24313624
MEGA6: Molecular Evolutionary Genetics Analysis version 6.0Q24498082
Genomic tagging of endogenous type IIbeta phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisationQ24684344
Phosphoinositides: tiny lipids with giant impact on cell regulationQ27012953
Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localizationQ28115612
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphateQ28254402
Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophilsQ28327099
AP-1 and clathrin are essential for secretory granule biogenesis in DrosophilaQ30501068
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumorsQ33804459
Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoformQ34146977
Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila developmentQ36762659
Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune systemQ37086526
PIP4K and the role of nuclear phosphoinositides in tumour suppressionQ38366482
Control of diverse subcellular processes by a single multi-functional lipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2].Q38861831
TOM1 is a PI5P effector involved in the regulation of endosomal maturationQ38919971
PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4KalphaQ39687546
Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephronQ39946401
Phosphatidylinositol 5-phosphate 4-kinase regulates early endosomal dynamics during clathrin-mediated endocytosis.Q41189491
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectbiophysicsQ7100
Lipid MediatorsQ61632695
enzyme activityQ22035510
P304page(s)BSR20182210
P577publication date2019-02-19
P1433published inBioscience ReportsQ2790714
P1476titleFunctional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes
P478volume39