Oral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae

scientific article published on August 1997

Oral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID175440
P698PubMed publication ID9234763

P2093author name stringT Zhang
S B Calderwood
S L Stanley
E T Ryan
M A Baker
J R Butterton
P2860cites workM cell transport of Vibrio cholerae from the intestinal lumen into Peyer's patches: a mechanism for antigen sampling and for microbial transepithelial migrationQ45717806
Expression of a recombinant Entamoeba histolytica antigen in a Salmonella typhimurium vaccine strainQ50168662
Insertion of a HIV-1-neutralizing epitope in a surface-exposed internal region of the cholera toxin B-subunitQ54191083
Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR.Q54378370
Development of a live, oral, attenuated vaccine against El Tor choleraQ57924437
Initial clinical studies of CVD 112 Vibrio cholerae O139 live oral vaccine: safety and efficacy against experimental challengeQ57924808
Duration of infection-derived immunity to choleraQ70831304
Protection against amebic liver abscess formation in the severe combined immunodeficient mouse by human anti-amebic antibodiesQ71616346
AmebiasisQ71716561
Antibodies to the serine rich Entamoeba histolytica protein (SREHP) prevent amoebic liver abscess in severe combined immunodeficient (SCID) miceQ72155700
A recombinant cysteine-rich section of the Entamoeba histolytica galactose-inhibitable lectin is efficacious as a subunit vaccine in the gerbil model of amebic liver abscessQ72592782
Use of the Vibrio cholerae irgA gene as a locus for insertion and expression of heterologous antigens in cholera vaccine strainsQ72746081
THE TOXIC EFFECT OF ENTAMOEBA HISTOLYTICA ON LEUCOCYTESQ76966939
Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin IQ24651553
Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine developmentQ28485732
Emergence of a new cholera pandemic: molecular analysis of virulence determinants in Vibrio cholerae O139 and development of a live vaccine prototypeQ30420490
Adherence of Entamoeba histolytica trophozoites to rat and human colonic mucosa.Q30451145
Human secretory immunoglobulin A anti-Entamoeba histolytica antibodies inhibit adherence of amebae to MDCK cellsQ30451207
Cloning and expression of a membrane antigen of Entamoeba histolytica possessing multiple tandem repeatsQ33256212
Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memoryQ34225394
Comparative effectiveness of the cholera toxin B subunit and alkaline phosphatase as carriers for oral vaccinesQ34520511
Chinese hamster ovary cells deficient in N-acetylglucosaminyltransferase I activity are resistant to Entamoeba histolytica-mediated cytotoxicityQ35088208
Protection of gerbils from amebic liver abscess by immunization with recombinant Entamoeba histolytica 29-kilodalton antigen.Q35383979
Oral immunization with the dodecapeptide repeat of the serine-rich Entamoeba histolytica protein (SREHP) fused to the cholera toxin B subunit induces a mucosal and systemic anti-SREHP antibody response.Q35400277
Local and systemic antibody responses to dextran-cholera toxin B subunit conjugatesQ35413377
Heterologous antigen expression in Vibrio cholerae vector strainsQ35423953
Oral immunization with an attenuated vaccine strain of Salmonella typhimurium expressing the serine-rich Entamoeba histolytica protein induces an antiamebic immune response and protects gerbils from amebic liver abscessQ35486883
Development of a germfree mouse model of Vibrio cholerae infection.Q35526942
Coexpression of the B subunit of Shiga toxin 1 and EaeA from enterohemorrhagic Escherichia coli in Vibrio cholerae vaccine strainsQ35548775
Protection of gerbils from amebic liver abscess by immunization with a recombinant Entamoeba histolytica antigen.Q35775983
Potential for reacquisition of cholera enterotoxin genes by attenuated Vibrio cholerae vaccine strain CVD 103-HgR.Q35777337
Protection of gerbils from amebic liver abscess by immunization with a recombinant protein derived from the 170-kilodalton surface adhesin of Entamoeba histolyticaQ35783115
Progress towards an amebiasis vaccineQ35846125
CTX genetic element encodes a site-specific recombination system and an intestinal colonization factor.Q36262564
Positive transcriptional regulation of an iron-regulated virulence gene in Vibrio choleraeQ37395794
The liver and IgA: immunological, cell biological and clinical implicationsQ38619047
Protective immunity to Shiga-like toxin I following oral immunization with Shiga-like toxin I B-subunit-producing Vibrio cholerae CVD 103-HgR.Q39824053
Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant.Q40762647
Genetic fusion of a non-toxic heat-stable enterotoxin-related decapeptide antigen to cholera toxin B-subunitQ41877655
The serine-rich Entamoeba histolytica protein is a phosphorylated membrane protein containing O-linked terminal N-acetylglucosamine residuesQ42066846
An optimized freeze-squeeze method for the recovery of DNA fragments from agarose gelsQ43806909
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectcholeraQ12090
Entamoeba histolyticaQ131027
Vibrio choleraeQ160821
immunizationQ1415366
attenuated vaccineQ1810913
P304page(s)3118-3125
P577publication date1997-08-01
P1433published inInfection and ImmunityQ6029193
P1476titleOral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae antibody responses in mice
P478volume65

Reverse relations

cites work (P2860)
Q34484003A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mic
Q50126055A cloning vector for efficient generation of cholera toxin B gene fusions for epitope screening
Q52684483A self-assembling whole cell vaccine antigen presentation platform.
Q24598726Cholera toxin: a paradigm of a multifunctional protein
Q35098194Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera
Q36045133Construction and Evaluation of a Safe, Live, Oral Vibrio cholerae Vaccine Candidate, IEM108
Q36480147Construction of a Vibrio cholerae prototype vaccine strain O395-N1-E1 which accumulates cell-associated cholera toxin B subunit
Q34003042Development of a DeltaglnA balanced lethal plasmid system for expression of heterologous antigens by attenuated vaccine vector strains of Vibrio cholerae
Q35896020Enteric pathogens as vaccine vectors for foreign antigen delivery
Q34403586Evaluation in mice of a conjugate vaccine for cholera made from Vibrio cholerae O1 (Ogawa) O-specific polysaccharide
Q37002887Exploiting cholera vaccines as a versatile antigen delivery platform
Q30407857Expression, purification, and evaluation of recombinant LecA as a candidate for an amebic colitis vaccine
Q77613864Host-pathogen interaction in amebiasis and progress in vaccine development
Q34003489In vitro and in vivo analyses of constitutive and in vivo-induced promoters in attenuated vaccine and vector strains of Vibrio cholerae
Q34000827In vivo expression and immunoadjuvancy of a mutant of heat-labile enterotoxin of Escherichia coli in vaccine and vector strains of Vibrio cholerae
Q34003405Optimizing the germfree mouse model for in vivo evaluation of oral Vibrio cholerae vaccine and vector strains
Q30441436Participation of the serine-rich Entamoeba histolytica protein in amebic phagocytosis of apoptotic host cells
Q35375735Progress towards development of a vaccine for amebiasis.
Q55042601Sublingual Adjuvant Delivery by a Live Attenuated Vibrio cholerae-Based Antigen Presentation Platform.
Q39676828Surface display of foreign epitopes on the Lactobacillus brevis S-layer
Q38185911The future for vaccine development against Entamoeba histolytica
Q36445329The major subunit of the toxin-coregulated pilus TcpA induces mucosal and systemic immunoglobulin A immune responses in patients with cholera caused by Vibrio cholerae O1 and O139.
Q35867213Transcutaneous immunization with a Vibrio cholerae O1 Ogawa synthetic hexasaccharide conjugate following oral whole-cell cholera vaccination boosts vibriocidal responses and induces protective immunity in mice
Q37386803Transcutaneous immunization with a synthetic hexasaccharide-protein conjugate induces anti-Vibrio cholerae lipopolysaccharide responses in mice

Search more.