Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes

scientific article published on 16 April 2015

Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2015/487816
P932PMC publication ID4415477
P698PubMed publication ID25961053
P5875ResearchGate publication ID275724181

P50authorCharles V JacksonQ96204456
Karen ZimmermanQ96204457
P2093author name stringRichard G Peterson
Michael K Hansen
Norman Huebert
Willem de Winter
P2860cites workEvacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressureQ24624286
Assessment of pancreatic β-cell function: review of methods and clinical applicationsQ26829445
Recent advances in the molecular genetics of type 2 diabetes mellitusQ26996335
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Banting lecture 1988. Role of insulin resistance in human diseaseQ29547283
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participantsQ29614188
Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventionsQ30415102
AVE8134, a novel potent PPARα agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic ratsQ33567011
A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus.Q51501369
Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study.Q54103713
Selective breeding for diet-induced obesity and resistance in Sprague-Dawley ratsQ73645282
Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty ratsQ87405336
Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetesQ33846858
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Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitusQ37141727
CRP and adiponectin and its oligomers in the metabolic syndrome: evaluation of new laboratory-based biomarkersQ37148493
Skeletal changes associated with the onset of type 2 diabetes in the ZDF and ZDSD rodent modelsQ37162300
Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM ratQ37200126
Genetic determinants and molecular pathways in the pathogenesis of Type 2 diabetesQ37348327
Loss of coupling between calcium influx, energy consumption and insulin secretion associated with development of hyperglycaemia in the UCD-T2DM rat model of type 2 diabetesQ37372966
The use of animal models in the study of diabetes mellitus.Q37469634
Age-Related Differences in Response to High-Fat Feeding on Adipose Tissue and Metabolic Profile in ZDSD RatsQ37515390
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes.Q37571073
Nanoscale changes in collagen are reflected in physical and mechanical properties of bone at the microscale in diabetic rats.Q37621815
Diabetes and insulin resistance in pediatric obesityQ37957451
The prevalence of metabolic syndrome in children: a systematic review of the literatureQ38068227
Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.Q39648063
Characterization of diabetic neuropathy in the Zucker diabetic Sprague-Dawley rat: a new animal model for type 2 diabetesQ41834115
A new obesity-prone, glucose-intolerant rat strain (F.DIO).Q44509590
Mode of onset of type 2 diabetes from normal or impaired glucose toleranceQ44704987
A genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat.Q46274158
Age-dependent development of metabolic derangement and effects of intervention with pioglitazone in Zucker diabetic fatty ratsQ46619834
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectmetabolic syndromeQ657193
type 2 diabetesQ3025883
P304page(s)487816
P577publication date2015-04-16
P1433published inJournal of Diabetes ResearchQ26841822
P1476titleCharacterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes
P478volume2015

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cites work (P2860)
Q38822212Alternatives to the Streptozotocin-Diabetic Rodent.
Q42402817Changes in the Fracture Resistance of Bone with the Progression of Type 2 Diabetes in the ZDSD Rat.
Q58737185Effects of glucagon-like peptide 1 analogs in combination with insulin on myocardial infarct size in rats with type 2 diabetes mellitus
Q33825537Glucose dysregulation and response to common anti-diabetic agents in the FATZO/Pco mouse.
Q39722024Modeling the Disease Progression from Healthy to Overt Diabetes in ZDSD Rats
Q49804048The Nile Rat (Arvicanthis niloticus) as a Superior Carbohydrate-Sensitive Model for Type 2 Diabetes Mellitus (T2DM).
Q41965910The ZDSD rat: a novel model of diabetic nephropathy
Q90667295Type 2 diabetes mellitus in the Goto-Kakizaki rat impairs microvascular function and contributes to premature skeletal muscle fatigue
Q30833537Uninephrectomized High-Fat-Fed Nicotinamide-Streptozotocin-Induced Diabetic Rats: A Model for the Investigation of Diabetic Nephropathy in Type 2 Diabetes.
Q42315902Wound Healing Delay in the ZDSD Rat.

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