Brain barrier systems: a new frontier in metal neurotoxicological research

scientific article published on October 2003

Brain barrier systems: a new frontier in metal neurotoxicological research is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0041-008X(03)00251-5
P932PMC publication ID3982148
P698PubMed publication ID14554098
P5875ResearchGate publication ID9054611

P50authorJean-François Ghersi-EgeaQ43111355
Michael AschnerQ64778814
P2093author name stringWei Zheng
P2860cites workUptake of lead and iron by divalent metal transporter 1 in yeast and mammalian cellsQ24301734
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter geneQ28244982
Neurotoxicology of the brain barrier system: new implicationsQ28344572
Manganese inhibits mitochondrial aconitase: a mechanism of manganese neurotoxicityQ28368301
Developmental patterns of gene expression of secreted proteins in brain and choroid plexusQ28580678
Transthyretin: a choroid plexus-specific transport protein in human brain. The 1986 S. Weir Mitchell awardQ28609126
Manganese neurotoxicity: a review of clinical features, imaging and pathology.Q30578662
Structure and expression of the transthyretin gene in the choroid plexus: a model for the study of the mechanism of evolutionQ31793034
The cell biology of the blood-brain barrier.Q33593387
A FOLLOW-UP STUDY OF LEAD WORKERSQ33639325
Manganese uptake and distribution in the central nervous system (CNS).Q33673034
Alteration of iron homeostasis following chronic exposure to manganese in ratsQ33865538
Choroid plexus in the central nervous system: biology and physiopathologyQ33910198
Toxicology of choroid plexus: special reference to metal-induced neurotoxicitiesQ34018855
Differential cytotoxicity of Mn(II) and Mn(III): special reference to mitochondrial [Fe-S] containing enzymesQ34018864
Inhibition by lead of production and secretion of transthyretin in the choroid plexus: its relation to thyroxine transport at blood-CSF barrierQ34018868
Aconitase, a two-faced protein: enzyme and iron regulatory factorQ34061037
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitorsQ34065800
Methylmercury poisoning: long-term clinical, radiological, toxicological, and pathological studies of an affected familyQ34342942
Choroid plexus transporters for drugs and other xenobioticsQ34775009
DMT1: a mammalian transporter for multiple metalsQ35061952
Iron regulation in the brain: histochemical, biochemical, and molecular considerationsQ35753915
Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.Q35796864
Mechanisms of lead neurotoxicityQ36485580
Chronic lead exposure alters transthyretin concentration in rat cerebrospinal fluid: the role of the choroid plexusQ36819696
Lead exposure promotes translocation of protein kinase C activities in rat choroid plexus in vitro, but not in vivoQ37183827
Inhibition of astroglia-induced endothelial differentiation by inorganic lead: a role for protein kinase CQ37295294
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugsQ37355653
Transport of L-[125I]thyroxine by in situ perfused ovine choroid plexus: inhibition by lead exposure.Q37693748
The effects of methylmercury on the developing brainQ38663405
A morphological and chemical study of calcification of the choroid plexusQ39462127
Regulating the fate of mRNA: the control of cellular iron metabolismQ40851091
The possible role of iron in the etiopathology of Parkinson's diseaseQ40868666
Immunohistochemical localization of the murine transferrin receptor (TfR) on blood-tissue barriers using a novel anti-TfR monoclonal antibody.Q41021527
Astrocytes as modulators of mercury-induced neurotoxicity.Q41404572
Uptake of methylmercury in the rat brain: effects of amino acidsQ42210034
Induction of metallothionein mRNA and protein in murine astrocyte culturesQ42557543
Abnormal iron deposition associated with lipid peroxidation in transgenic mice expressing interleukin-6 in the brainQ44193172
Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrinQ44300759
Manganese distribution across the blood-brain barrier. II. Manganese efflux from the brain does not appear to be carrier mediatedQ44300763
Hydrocephalus following prenatal methylmercury poisoningQ45190418
Effect of the dural application of Zenker's solution on the feline brainQ45307070
The distribution of inorganic lead in guinea pig brain and neural barrier tissues in control and lead-poisoned animalsQ46409631
Postnatal developmental changes in blood flow to choroid plexuses and cerebral cortex of the rat.Q48125181
Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobioticsQ48157328
Experimental lead encephalopathy in the suckling rat: concentration of lead in cellular fractions enriched in brain capillariesQ48189300
Manganese (Mn) transport across the rat blood-brain barrier: saturable and transferrin-dependent transport mechanismsQ48195948
Rapid Brain Uptake of Manganese(II) Across the Blood‐Brain BarrierQ48246042
A sensitive post-DAB enhancement technique for demonstration of iron in the central nervous systemQ48280696
Differential expression of the insulin-like growth factor II and transthyretin genes in the developing rat choroid plexus.Q48324015
Lead encephalopathy in neonatal Long-Evans rats: morphologic studiesQ48327849
Iron uptake in blood-brain barrier endothelial cells cultured in iron-depleted and iron-enriched media.Q48403840
Iron and transferrin uptake by brain and cerebrospinal fluid in the ratQ48420705
Electronic spin resonance detection of superoxide and hydroxyl radicals during the reductive metabolism of drugs by rat brain preparations and isolated cerebral microvesselsQ48449959
Drug metabolism in in vitro organotypic and cellular models of mammalian central nervous system: activities of membrane-bound epoxide hydrolase and NADPH-cytochrome P-450 (c) reductase.Q48453203
Uptake and distribution of iron and transferrin in the adult rat brain.Q48459489
Pathogenesis of lead encephalopathy. Uptake of lead and reaction of brain capillariesQ48504066
Changes in the integrity of the blood-brain barrier in suckling rats with low dose lead encephalopathyQ48545701
Transferrin receptor on endothelium of brain capillariesQ48602638
Does the choroid plexus really protect the brain from lead?Q48634639
Lead-induced abnormalities in blood-brain barrier permeability in experimental chronic toxicityQ48641331
Saturable Transport of Manganese(II) Across the Rat Blood-Brain BarrierQ48662312
Manganese metabolism is impaired in the Belgrade laboratory rat.Q48665039
Choroid plexus protects cerebrospinal fluid against toxic metalsQ48733228
Acute 3-nitropropionic acid intoxication induces striatal astrocytic cell death and dysfunction of the blood-brain barrier: involvement of dopamine toxicityQ48737547
Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat.Q48855463
Immunohistochemical localization of intraneuronal transferrin receptor immunoreactivity in the adult mouse central nervous systemQ48858856
Distribution of injected iron 59 and manganese 54 in hypotransferrinemic miceQ48937155
Transport of lead-203 at the blood-brain barrier during short cerebrovascular perfusion with saline in the rat.Q49089870
The blood-brain barrier following experimental subarachnoid hemorrhage. Part 2: Response to mercuric chloride infusion.Q50930036
Morphology and morphogenesis of lead encephalopathyQ51245697
Lead-induced alterations of glial fibrillary acidic protein (GFAP) in the developing rat brain.Q52200967
Prenatal and postnatal lead exposure induces 70 kDa heat shock protein in young rat brain prior to changes in astrocyte cytoskeleton.Q53747443
Electron probe microanalysis of isolated brain capillaries poisoned with lead.Q54732031
Anin VitroStudy ofm-Dinitrobenzene Toxicity on the Cellular Components of the Blood–Brain Barrier, Astrocytes and Endothelial CellsQ57076440
Astrocytes induce blood–brain barrier properties in endothelial cellsQ57318253
Picomolar concentrations of lead stimulate brain protein kinase CQ59093839
The G185R mutation disrupts function of the iron transporter Nramp2Q61186162
Diacylglycerol inhibits gap junctional communication in cultured epidermal cells: evidence for a role of protein kinase CQ67278783
Observations on the chemical nature of lead in human blood serumQ68269463
Thyroid hormones and brain developmentQ68948550
Mercury level and histochemical distribution in a human brain with Minamata disease following a long-term clinical course of twenty-six yearsQ69366506
Retention and distribution of manganese in the mouse brain following acute exposure on postnatal day 0, 7, 14 or 42: an autoradiographic and gamma counting studyQ69671752
Antioxidant enzymes and related trace elements in aging brain capillaries and choroid plexusQ69681064
Changes of activity and ultrastructural localization of alkaline phosphatase in cerebral cortical microvessels of rat after single intraperitoneal administration of mercuric chlorideQ72153883
Choroid plexus as a protective sink for heavy metals?Q72549464
Lead transport and binding by human erythrocytes in vitroQ72806808
Waiting for frataxinQ93899465
P433issue1
P304page(s)1-11
P577publication date2003-10-01
P1433published inToxicology and Applied PharmacologyQ2446974
P1476titleBrain barrier systems: a new frontier in metal neurotoxicological research
P478volume192