Cytokine regulation of pulmonary fibrosis in scleroderma

scientific article published on December 1, 2003

Cytokine regulation of pulmonary fibrosis in scleroderma is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S1359-6101(03)00060-1
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S1359610103000601?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S1359610103000601?httpAccept=text/xml
P698PubMed publication ID14563355

P2093author name stringBarbara White
Sergei P. Atamas
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Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2.Q44185732
Association of novel polymorphisms with the expression of SPARC in normal fibroblasts and with susceptibility to sclerodermaQ44213853
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Role of p38 MAPK in Transforming Growth Factor β Stimulation of Collagen Production by Scleroderma and Healthy Dermal FibroblastsQ60537806
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Oncostatin M Stimulates Transcription of the Human α2(I) Collagen Gene via the Sp1/Sp3-binding SiteQ60537839
Increased Expression of CD40 Ligand in Activated CD4+T Lymphocytes of Systemic Sclerosis PatientsQ61628558
Circulating gamma/delta T lymphocytes from systemic sclerosis (SSc) patients display a T helper (Th) 1 polarizationQ61733728
Late CD8+ lymphocytic alveolitis after allogeneic bone marrow transplantation and chronic graft-versus-host diseaseQ62929586
Cytokine production and serum levels in systemic sclerosisQ67593361
Increased sensitivity of scleroderma fibroblasts in culture to stimulation of protein and collagen synthesis by serumQ67672931
Growth and characterization of fibroblasts obtained from bronchoalveolar lavage of patients with sclerodermaQ67999243
Lymphokine regulation of inflammatory processes: interleukin-4 stimulates fibroblast proliferationQ68097944
Human recombinant interleukin-4 induces proliferation and interleukin-6 production by cultured human skin fibroblastsQ68167537
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Transcription and expression of transforming growth factor type beta in the skin of progressive systemic sclerosis: a mediator of fibrosis?Q68700570
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Interleukin-1 inhibits the synthesis of collagen by fibroblastsQ68812123
Prevalence of scleroderma spectrum disorders in the general population of South CarolinaQ69742881
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Transforming growth factor (TGF beta) decreases the proliferation of human bone marrow fibroblasts by inhibiting the platelet-derived growth factor (PDGF) bindingQ70226496
Interleukin 1 receptor on fibroblasts from systemic sclerosis patients induces excessive functional responses to interleukin 1 betaQ70534310
Investigation of type I and type III collagens of the lung in progressive systemic sclerosisQ70719615
Expression of tumour necrosis factor-alpha in cryptogenic fibrosing alveolitisQ70768301
Effect of IL-6 on alveolar fibroblast proliferation in interstitial lung diseasesQ71089537
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Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factorQ71381389
c-myb proto-oncogene is expressed by quiescent scleroderma fibroblasts and, unlike B-myb gene, does not correlate with proliferationQ71383665
Skewing of the CD8+ T-cell repertoire in the lungs of patients with systemic sclerosisQ71574576
Restricted T-cell antigen receptor repertoire in bronchoalveolar T cells from normal humansQ71688731
Chemotactic cytokines mediate leukocyte recruitment in fibrotic lung diseaseQ71725323
Elevated levels of eosinophil major basic protein in the sera of patients with systemic sclerosisQ71880216
Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with sclerodermaQ71965468
Expression of c-myc, c-myb, and c-sis in fibroblasts from affected and unaffected skin of patients with systemic sclerosisQ71994942
Interleukin-4 acts as a potent stimulator for expression of monocyte chemoattractant JE/MCP-1 in mouse peritoneal macrophagesQ72159597
Oncostatin M stimulates collagen and glycosaminoglycan production by cultured normal dermal fibroblasts: insensitivity of sclerodermal and keloidal fibroblastsQ72353150
Hapten-immune pulmonary interstitial fibrosis (HIPIF) in mice requires both CD4+ and CD8+ T lymphocytesQ72656480
Increased levels of endothelin-1 in bronchoalveolar lavage fluid from patients with systemic sclerosis contribute to fibroblast mitogenic activity in vitroQ72694022
Interleukin-6 is an autocrine growth factor for murine lung fibroblast subsetsQ72769840
Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMPQ73042158
Clinical significance of MCP-1 levels in BALF and serum in patients with interstitial lung diseasesQ73068961
Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosisQ73076887
Scleroderma fibroblasts show increased responsiveness to endothelial cell-derived IL-1 and bFGFQ73081964
Role of apoptosis and transforming growth factor beta1 in fibroblast selection and activation in systemic sclerosisQ73092717
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Interferon-gamma and interleukin-4 differentially regulate ICAM-1 and VCAM-1 expression on human lung fibroblastsQ73208038
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Deficient Smad7 expression: a putative molecular defect in sclerodermaQ34021184
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Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repairQ34437758
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Complex cytokine regulation of tissue fibrosisQ35017833
Roles for insulin-like growth factor I and transforming growth factor-beta in fibrotic lung diseaseQ35022204
Smooth muscle differentiation in scleroderma fibroblastic cellsQ35811553
Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblastsQ36231258
Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activationQ36231523
Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in miceQ36287478
Gamma interferon is the lymphokine and beta interferon the monokine responsible for inhibition of fibroblast collagen production and late but not early fibroblast proliferationQ36350622
Stimulation of fibroblast chemotaxis by human recombinant tumor necrosis factor alpha (TNF-alpha) and a synthetic TNF-alpha 31-68 peptideQ36354096
Human eosinophils regulate human lung- and skin-derived fibroblast properties in vitro: a role for transforming growth factor beta (TGF-beta)Q36429520
TGF-beta 1 stimulates cultured human fibroblasts to proliferate and produce tissue-like fibroplasia: a fibronectin matrix-dependent eventQ36844219
Thrombin differentiates normal lung fibroblasts to a myofibroblast phenotype via the proteolytically activated receptor-1 and a protein kinase C-dependent pathwayQ38296390
Negative modulation of alpha1(I) procollagen gene expression in human skin fibroblasts: transcriptional inhibition by interferon-gammaQ38327005
C-myb, but not B-myb, upregulates type I collagen gene expression in human fibroblastsQ38328184
Characterization of the c-Myb-responsive region and regulation of the human type I collagen alpha 2 chain gene by c-Myb.Q38361182
Fibroblast chemotaxis induction by human recombinant interleukin-4. Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70-88 and 89-122.Q40348725
Interstitial lung disease of systemic sclerosis.Q40468554
Evidence of fibroblast heterogeneity and the role of fibroblast subpopulations in fibrosisQ40625104
Human mast cells stimulate fibroblast proliferation, collagen synthesis and lattice contraction: a direct role for mast cells in skin fibrosisQ40740841
Synergy between CD40 ligation and IL-4 on fibroblast proliferation involves IL-4 receptor signalingQ40756159
The differentiation and function of myofibroblasts is regulated by mast cell mediatorsQ40768319
Role of stem cell factor and monocyte chemoattractant protein-1 in the interaction between fibroblasts and mast cells in fibrosisQ40802755
Influence of alternatively and classically activated macrophages on fibrogenic activities of human fibroblastsQ40852538
Thrombin stimulates the expression of PDGF in lung epithelial cellsQ40859180
Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of sclerodermaQ41005869
Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4Q41020866
Production of interleukin 13 by alveolar macrophages from normal and fibrotic lungQ41068693
Effect of histamine on proliferation of normal human adult lung fibroblastsQ41131152
T lymphocytes and silica-induced pulmonary inflammation and fibrosis in miceQ41207867
Elevated plasma histamine levels in systemic sclerosis (scleroderma).Q41224949
Scleroderma bronchoalveolar lavage fluid contains thrombin, a mediator of human lung fibroblast proliferation via induction of platelet-derived growth factor alpha-receptorQ41479307
Alternative splice variants of cytokines: making a listQ41604776
Significant Correlation Between Connective Tissue Growth Factor Gene Expression and Skin Sclerosis in Tissue Sections from Patients with Systemic SclerosisQ41679291
Connective tissue growth factor: a mediator of TGF-beta action on fibroblastsQ41700398
Secretion and binding of transforming growth factor beta by scleroderma and normal dermal fibroblasts.Q41735665
The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblastsQ41766529
Interleukin-1 beta prevents the stimulatory effect of transforming growth factor-beta on collagen gene expression in human skin fibroblastsQ41771855
Transforming growth factor beta (TGF beta) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblastsQ41955517
Gamma-interferon inhibits extracellular matrix synthesis and remodeling in collagen lattice cultures of normal and scleroderma skin fibroblastsQ41963379
Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblastsQ42120199
Enhanced production of interleukin-1 and tumor necrosis factor alpha by cultured peripheral blood monocytes from patients with sclerodermaQ42122302
Eosinophils adhere to and stimulate replication of lung fibroblasts 'in vitro'.Q42473152
Increased phosphorylation of transcription factor Sp1 in scleroderma fibroblasts: association with increased expression of the type I collagen geneQ42494727
CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signalingQ42498294
Peripheral blood T lymphocytes from systemic sclerosis patients show both Th1 and Th2 activationQ42505740
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodelingQ42518399
Up-regulation of IL-8 secretion by alveolar macrophages from patients with fibrosing alveolitis: a subpopulation analysisQ73211913
Elevated serum tumor necrosis factor-alpha levels in patients with systemic sclerosis: association with pulmonary fibrosisQ73218951
Interferon-gamma inhibits experimental renal fibrosisQ73265447
Mast cell involvement in normal human skin wound healing: expression of monocyte chemoattractant protein-1 is correlated with recruitment of mast cells which synthesize interleukin-4 in vivoQ73368701
Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosisQ73385986
Thrombin upregulates interleukin-8 in lung fibroblasts via cleavage of proteolytically activated receptor-I and protein kinase C-gamma activationQ73407827
Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblastsQ73478890
Antagonistic effects of interferon-gamma and interleukin-4 on fibroblast culturesQ73555252
Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptorsQ73565858
Differential effects of necrotic or apoptotic cell uptake on antigen presentation by macrophagesQ73567478
Pulmonary capillary endothelial dysfunction in early systemic sclerosisQ73792172
Endothelin-1 secretion by alveolar macrophages in systemic sclerosisQ73885856
Cyclophosphamide is associated with pulmonary function and survival benefit in patients with scleroderma and alveolitisQ73905511
Depletion of protein kinase Cepsilon in normal and scleroderma lung fibroblasts has opposite effects on tenascin expressionQ74024142
Chemokine expression by systemic sclerosis fibroblasts: abnormal regulation of monocyte chemoattractant protein 1 expressionQ74024150
Oncostatin M stimulates the growth of dermal fibroblasts via a mitogen-activated protein kinase-dependent pathwayQ74108320
Decreased susceptibility to Fas-induced apoptosis of systemic sclerosis dermal fibroblastsQ74242439
Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosisQ74267115
Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosisQ74452502
Role of connective tissue growth factor in profibrotic action of transforming growth factor-beta: a potential target for preventing renal fibrosisQ74568092
High expression and autoinduction of monocyte chemoattractant protein-1 in scleroderma fibroblastsQ74602329
Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesisQ77179324
Animal model of sclerotic skin. V: Increased expression of alpha-smooth muscle actin in fibroblastic cells in bleomycin-induced sclerodermaQ77460965
Radiation-induced pulmonary fibrosis: examination of chemokine and chemokine receptor familiesQ77625551
Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activationQ77743777
Production of type 2 cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosisQ77872996
Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the ratQ77900005
Expression of C-C chemokines in bronchoalveolar lavage cells from patients with granulomatous lung diseasesQ77928975
Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis: MCP-1 and MIP-1alpha may be involved in the development of pulmonaryQ77995169
Gene expression in bronchoalveolar lavage cells from scleroderma patientsQ77995648
Anti-sclerotic effect of transforming growth factor-beta antibody in a mouse model of bleomycin-induced sclerodermaQ78021748
Antagonistic effects of an alternative splice variant of human IL-4, IL-4delta2, on IL-4 activities in human monocytes and B cellsQ78109962
Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosisQ78169196
Transforming growth factor beta induces fibroblast fibrillin-1 matrix formationQ78505493
Abnormal expression of intracellular cytokines and chemokine receptors in peripheral blood T lymphocytes from patients with systemic sclerosisQ78576655
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
pulmonary fibrosisQ32446
P304page(s)537-550
P577publication date2003-12-01
P1433published inCytokine and Growth Factor ReviewsQ15763303
P1476titleCytokine regulation of pulmonary fibrosis in scleroderma
P478volume14

Reverse relations

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