| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | María C Ovejero-Benito | Q84240141 |
| José M. Frade | Q42031651 | ||
| P2093 | author name string | José M Frade | |
| María C Ovejero-Benito | |||
| P2860 | cites work | Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models | Q82297941 |
| The cell cycle and cancer | Q85077091 | ||
| Cell cycle, CDKs and cancer: a changing paradigm | Q24314465 | ||
| The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex | Q24314687 | ||
| Cyclin A is required at two points in the human cell cycle | Q24329048 | ||
| Cyclin B targets p34cdc2 for tyrosine phosphorylation | Q24561468 | ||
| The roles of cyclin A2, B1, and B2 in early and late mitotic events | Q24610068 | ||
| Heterogenic final cell cycle by chicken retinal Lim1 horizontal progenitor cells leads to heteroploid cells with a remaining replicated genome | Q27334307 | ||
| CDK inhibitors: positive and negative regulators of G1-phase progression | Q27860983 | ||
| Cdc25 protein phosphatases in cell proliferation | Q28237377 | ||
| A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase | Q28247022 | ||
| Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints | Q28266170 | ||
| Cdks, cyclins and CKIs: roles beyond cell cycle regulation | Q28294632 | ||
| Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity | Q28505504 | ||
| Regulation of neuron survival and death by p130 and associated chromatin modifiers | Q28567953 | ||
| The cyclin-dependent kinase inhibitors p19(Ink4d) and p27(Kip1) are coexpressed in select retinal cells and act cooperatively to control cell cycle exit | Q43924923 | ||
| Kainic acid-induced apoptosis in cerebellar granule neurons: an attempt at cell cycle re-entry | Q43945482 | ||
| Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery | Q44017737 | ||
| Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex | Q44085921 | ||
| Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice | Q44216067 | ||
| Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients | Q44235388 | ||
| Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta | Q44264442 | ||
| Expression patterns of retinoblastoma protein in Parkinson disease | Q44278829 | ||
| Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? | Q44391611 | ||
| Inhibition of cell cycle pathway by flavopiridol promotes survival of cerebellar granule cells after an excitotoxic treatment | Q44650627 | ||
| Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats | Q44776053 | ||
| Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons | Q28568084 | ||
| Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons | Q28580633 | ||
| Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat | Q28583944 | ||
| Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase | Q28612124 | ||
| Regulation of ischemic neuronal death by E2F4-p130 protein complexes | Q28771402 | ||
| Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis | Q29618506 | ||
| Cell cycle checkpoint regulators reach a zillion | Q30413076 | ||
| E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. | Q33180163 | ||
| Constitutive expression of functionally active cyclin-dependent kinases and their binding partners suggests noncanonical functions of cell cycle regulators in differentiated neurons | Q33260829 | ||
| Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor | Q33591535 | ||
| Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits | Q33638849 | ||
| Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury | Q33852129 | ||
| Selective cell death of hyperploid neurons in Alzheimer's disease | Q33947138 | ||
| Brain-derived neurotrophic factor in neurodegenerative diseases | Q34017880 | ||
| Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. | Q34047944 | ||
| The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues | Q34057186 | ||
| Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system | Q34080329 | ||
| Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path? | Q34133245 | ||
| The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2 | Q34356650 | ||
| Neuronal apoptosis at the G1/S cell cycle checkpoint | Q34361816 | ||
| INK4 proteins, a family of mammalian CDK inhibitors with novel biological functions. | Q34656077 | ||
| Brain-derived neurotrophic factor-dependent cdk1 inhibition prevents G2/M progression in differentiating tetraploid neurons. | Q34760947 | ||
| Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s) | Q34972742 | ||
| The heterogenic final cell cycle of chicken retinal Lim1 horizontal cells is not regulated by the DNA damage response pathway | Q35046038 | ||
| Oxidative stress, cell cycle, and neurodegeneration | Q35086148 | ||
| The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease | Q35652312 | ||
| Cell cycle regulation of neuronal apoptosis in development and disease. | Q35690376 | ||
| Why do neurons enter the cell cycle? | Q35770109 | ||
| The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease | Q35829694 | ||
| Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner | Q35924870 | ||
| Cyclins and CDKS in development and cancer: lessons from genetically modified mice | Q36251164 | ||
| Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents | Q36255573 | ||
| Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice | Q36388809 | ||
| Retinal horizontal cells lacking Rb1 sustain persistent DNA damage and survive as polyploid giant cells. | Q36394549 | ||
| Genetic evidence for p75NTR-dependent tetraploidy in cortical projection neurons from adult mice. | Q45327572 | ||
| Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. | Q48094020 | ||
| Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease | Q48124201 | ||
| Neuronal expression of cell cycle-related proteins after brain ischaemia in man. | Q48132342 | ||
| BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies | Q48159820 | ||
| P38 MAP kinase is activated at early stages in Alzheimer's disease brain | Q48174683 | ||
| Localization and expression of cdc2 and cdk4 in Alzheimer brain tissue | Q48212642 | ||
| RB and Cdc2 expression in brain: correlations with 3H-thymidine incorporation and neurogenesis. | Q48258122 | ||
| Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia hypoxia. | Q48295231 | ||
| The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons. | Q48368204 | ||
| Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice. | Q48414060 | ||
| Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. | Q48487273 | ||
| Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle. | Q48487594 | ||
| Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration. | Q48492166 | ||
| Constitutive Wee1 activity in adult brain neurons with M phase-type alterations in Alzheimer neurodegeneration. | Q48492209 | ||
| Up-regulation of cell division cycle (cdc) 2 kinase in neurons with early stage Alzheimer's disease neurofibrillary degeneration. | Q48498321 | ||
| Control of early cell death by BDNF in the chick retina. | Q48623139 | ||
| Cell cycle markers in the hippocampus in Alzheimer's disease. | Q48671520 | ||
| Staging of Alzheimer-type pathology: an interrater-intrarater study. | Q48674730 | ||
| Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. | Q48706959 | ||
| Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology. | Q48818986 | ||
| E2F4 expression patterns in SIV encephalitis. | Q48878785 | ||
| Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases. | Q49140750 | ||
| Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. | Q50793409 | ||
| Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. | Q52180282 | ||
| Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation. | Q52254715 | ||
| Gene profiling identifies commonalities in neuronal pathways in excitotoxicity: evidence favouring cell cycle re-activation in concert with oxidative stress. | Q53126269 | ||
| Cyclin-dependent kinases and cell-cycle transitions: does one fit all? | Q53451934 | ||
| Neuronal cell cycle re-entry mediates Alzheimer disease-type changes | Q64377402 | ||
| Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway | Q64380173 | ||
| Induction and modulation of cerebellar granule neuron death by E2F-1 | Q64380700 | ||
| Ki-67 immunoreactivity in Alzheimer's disease and other neurodegenerative disorders | Q72224719 | ||
| Unscheduled re-entry into the cell cycle induced by NGF precedes cell death in nascent retinal neurones | Q73514608 | ||
| Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage | Q73704447 | ||
| Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons | Q73863849 | ||
| The when and wheres of CDC25 phosphatases | Q36400579 | ||
| Implication of the transcription factor E2F-1 in the modulation of neuronal apoptosis. | Q36687582 | ||
| The cell cycle hypothesis of Alzheimer's disease: suggestions for drug development | Q36708036 | ||
| Role of cell cycle proteins in CNS injury | Q36778834 | ||
| The CDK Network: Linking Cycles of Cell Division and Gene Expression | Q36796443 | ||
| Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain | Q36990666 | ||
| Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity | Q37038517 | ||
| CDK inhibitors: cell cycle regulators and beyond | Q37081857 | ||
| The biology of neurotrophins, signalling pathways, and functional peptide mimetics of neurotrophins and their receptors | Q37090137 | ||
| Cyclin A-Cdk1 regulates the origin firing program in mammalian cells | Q37117765 | ||
| MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons | Q37261417 | ||
| Role of phosphorylation in p34cdc2 activation: identification of an activating kinase | Q37370012 | ||
| Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity | Q37375249 | ||
| Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease | Q37439838 | ||
| Cyclin-dependent kinases as a therapeutic target for stroke. | Q37445826 | ||
| Neural cell cycle dysregulation and central nervous system diseases | Q37556914 | ||
| Targeting p38 MAPK pathway for the treatment of Alzheimer's disease | Q37642107 | ||
| Molecular mechanisms of DNA replication checkpoint activation | Q37689837 | ||
| A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR). | Q37740907 | ||
| Mitosis in vertebrates: the G2/M and M/A transitions and their associated checkpoints | Q37824833 | ||
| Established and novel Cdk/cyclin complexes regulating the cell cycle and development. | Q37883204 | ||
| Control of neuronal ploidy during vertebrate development. | Q37883216 | ||
| Phosphatases driving mitosis: pushing the gas and lifting the brakes | Q37984845 | ||
| Cell cycle activation and aneuploid neurons in Alzheimer's disease | Q38005023 | ||
| FOXOs: signalling integrators for homeostasis maintenance | Q38074598 | ||
| GDNF, NGF and BDNF as therapeutic options for neurodegeneration. | Q38076581 | ||
| Cell cycle control across the eukaryotic kingdom | Q38097151 | ||
| E2F4 actively promotes the initiation and maintenance of nerve growth factor-induced cell differentiation | Q38321509 | ||
| Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycle | Q39942878 | ||
| Cdk1-FOXO1: a mitotic signal takes center stage in post-mitotic neurons | Q40490765 | ||
| p40MO15 associates with a p36 subunit and requires both nuclear translocation and Thr176 phosphorylation to generate cdk-activating kinase activity in Xenopus oocytes | Q40793691 | ||
| Why minimal is not optimal: driving the mammalian cell cycle--and drug discovery--with a physiologic CDK control network | Q41898356 | ||
| Nerve growth factor-induced cell cycle reentry in newborn neurons is triggered by p38MAPK-dependent E2F4 phosphorylation | Q42031613 | ||
| Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. | Q42439458 | ||
| A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F. | Q42458097 | ||
| DNA replication precedes neuronal cell death in Alzheimer's disease. | Q42502934 | ||
| Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease | Q42508999 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
| P433 | issue | 5 | |
| P921 | main subject | nervous system | Q9404 |
| cell | Q7868 | ||
| P1104 | number of pages | 9 | |
| P304 | page(s) | 712-720 | |
| P577 | publication date | 2015-01-01 | |
| P1433 | published in | Cell Cycle | Q1254166 |
| P1476 | title | Neuronal cell cycle: the neuron itself and its circumstances | |
| P478 | volume | 14 |
| Q48189570 | 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Alters Cell Cycle Progression in Human Neuroblastoma Cell Lines |
| Q42581569 | A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation |
| Q90405323 | A three-dimensional dementia model reveals spontaneous cell cycle re-entry and a senescence-associated secretory phenotype |
| Q47617752 | Aberrant activation of Cdc2/cyclin B1 is involved in initiation of cytoskeletal pathology in murine Niemann-Pick disease type C. |
| Q90230646 | Activation of cyclin D1 affects mitochondrial mass following traumatic brain injury |
| Q92099172 | Altered Features of Vimentin-containing Cells in Cerebrum of Tg(SOD1*G93A)1Gur Mice: A Preliminary Study on Cerebrum Endogenous Neural Precursor Cells in Amyotrophic Lateral Sclerosis |
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| Q52690916 | Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration. |
| Q92187388 | Cell Cycle Proteins as Key Regulators of Postmitotic Cell Death |
| Q58698855 | Cell cycle reentry triggers hyperploidization and synaptic dysfunction followed by delayed cell death in differentiated cortical neurons |
| Q36655192 | Characterization of neuropathology in the HIV-1 transgenic rat at different ages. |
| Q58605964 | Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury |
| Q89977186 | Contributions of DNA Damage to Alzheimer's Disease |
| Q59132736 | Evaluating the Remote Control of Programmed Cell Death, with or without a Compensatory Cell Proliferation |
| Q55339590 | Expression of Cyclin-D1 in Astrocytes Varies During Aging. |
| Q41813545 | Familial Alzheimer's Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants |
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| Q52367727 | Gene expression in retinal ischemic post-conditioning. |
| Q52723921 | Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death. |
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| Q48170413 | Iron Oxide Nanoparticles Induces Cell Cycle-Dependent Neuronal Apoptosis in Mice. |
| Q47935921 | LPS-induced inflammatory response triggers cell cycle reactivation in murine neuronal cells through retinoblastoma proteins induction. |
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