scholarly article | Q13442814 |
P50 | author | Reinhold G Erben | Q88598647 |
P2093 | author name string | Wei Huang | |
Beate Lanske | |||
René St-Arnaud | |||
Mohammed S Razzaque | |||
Takashi Taguchi | |||
Despina Sitara | |||
P2860 | cites work | The parathyroid hormone (PTH)/PTH-related peptide receptor mediates actions of both ligands in murine bone | Q22008500 |
Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23 | Q24290481 | ||
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis | Q24319751 | ||
Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia | Q24623628 | ||
Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice | Q28507303 | ||
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning | Q28508915 | ||
Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo | Q28572995 | ||
Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities | Q28587985 | ||
Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid | Q29614810 | ||
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism | Q29620323 | ||
FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting | Q34227442 | ||
Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets | Q35044977 | ||
Presentation of vitamin D deficiency | Q35280485 | ||
Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia | Q36576317 | ||
An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia. | Q40482177 | ||
Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders | Q40530218 | ||
Role of the vitamin D receptor in FGF23 action on phosphate metabolism | Q42156385 | ||
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process | Q42736434 | ||
Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets | Q43646694 | ||
Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. | Q44044824 | ||
Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia | Q44203982 | ||
Conventional and tissue-specific inactivation of the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1). | Q44273750 | ||
Rescue of the pseudo-vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyvitamin D3: biochemical, histomorphometric, and biomechanical analyses | Q44389591 | ||
Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) | Q44399738 | ||
Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia | Q44414604 | ||
Inactivation of the 25-hydroxyvitamin D 1alpha-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis | Q44739140 | ||
Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis | Q44779387 | ||
Rescue of the phenotype of CYP27B1 (1alpha-hydroxylase)-deficient mice | Q44958253 | ||
Hereditary 1,25-dihydroxyvitamin D resistant rickets due to a mutation causing multiple defects in vitamin D receptor function | Q45016610 | ||
Identification of a recurrent mutation in GALNT3 demonstrates that hyperostosis-hyperphosphatemia syndrome and familial tumoral calcinosis are allelic disorders | Q45187805 | ||
A novel GALNT3 mutation in a pseudoautosomal dominant form of tumoral calcinosis: evidence that the disorder is autosomal recessive | Q45345389 | ||
Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations | Q46471059 | ||
Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism | Q46585085 | ||
Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. | Q50941844 | ||
Investigation of the Mechanism for Abnormal Renal 25 Hydroxyvitamin D3-1-Hydroxylase Activity in the XLinkedHypMouse* | Q54471346 | ||
FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa. | Q54733425 | ||
Role of collagen-binding heat shock protein 47 and transforming growth factor-beta1 in conjunctival scarring in ocular cicatricial pemphigoid. | Q54782202 | ||
Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice | Q56767950 | ||
Evidence that low plasma 1,25-dihydroxyvitamin D causes intestinal malabsorption of calcium and phosphate in juvenile X-linked hypophosphatemic mice | Q68717307 | ||
Suppression of serum 1,25-dihydroxyvitamin D in humoral hypercalcemia of malignancy is caused by elaboration of a factor that inhibits renal 1,25-dihydroxyvitamin D3 production | Q69340174 | ||
FGF-23, vitamin D and calcification: the unholy triad | Q80394650 | ||
A novel recessive mutation in fibroblast growth factor-23 causes familial tumoral calcinosis | Q81353302 | ||
Absence of intraepidermal glycosyltransferase ppGalNac-T3 expression in familial tumoral calcinosis | Q81757273 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | vitamin D | Q175621 |
P304 | page(s) | 2161-2170 | |
P577 | publication date | 2006-12-01 | |
P1433 | published in | The American Journal of Pathology | Q4744259 |
P1476 | title | Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals | |
P478 | volume | 169 |
Q34126718 | 1,25-dihydroxyvitamin D3 treatment delays cellular aging in human mesenchymal stem cells while maintaining their multipotent capacity |
Q41889533 | 1alpha,25-dihydroxyvitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro. |
Q51308109 | A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia. |
Q37365294 | A systems biology preview of the relationships between mineral and metabolic complications in chronic kidney disease. |
Q41959145 | Ablation of systemic phosphate-regulating gene fibroblast growth factor 23 (Fgf23) compromises the dentoalveolar complex |
Q37418420 | Amelioration of the premature ageing-like features of Fgf-23 knockout mice by genetically restoring the systemic actions of FGF-23 |
Q36177303 | Arterial calcification and bone physiology: role of the bone-vascular axis |
Q40164192 | Biological activity of FGF-23 fragments |
Q47989110 | Biology of Fibroblast Growth Factor 23: From Physiology to Pathology |
Q37663859 | Bone mineral density in patients on maintenance dialysis |
Q90469042 | C-FGF23 peptide alleviates hypoferremia during acute inflammation |
Q37091865 | Calcium and phosphate homeostasis: concerted interplay of new regulators |
Q35912924 | Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport. |
Q27333726 | Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice |
Q37182735 | Does Fgf23-klotho activity influence vascular and soft tissue calcification through regulating mineral ion metabolism? |
Q82875571 | Does the downregulation of the FGF23 signaling pathway in hyperplastic parathyroid glands contribute to refractory secondary hyperparathyroidism in CKD patients? |
Q28085476 | Dysregulation of phosphate metabolism and conditions associated with phosphate toxicity |
Q36982323 | Endocrine functions of bone in mineral metabolism regulation. |
Q37991256 | Evidence for FGF23 involvement in a bone-kidney axis regulating bone mineralization and systemic phosphate and vitamin D homeostasis. |
Q37683399 | FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis |
Q37996937 | FGF23 and PTH--double agents at the heart of CKD. |
Q35707031 | FGF23 in skeletal modeling and remodeling |
Q36756061 | Fibroblast growth factor 23 and bone mineralisation |
Q33932297 | Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis |
Q37913097 | Fibroblast growth factor 23 as a phosphotropic hormone and beyond |
Q24604832 | Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes |
Q89506150 | Gene expression of matrix metalloproteinase 9 (MMP9), matrix metalloproteinase 13 (MMP13), vascular endothelial growth factor (VEGF) and fibroblast growth factor 23 (FGF23) in femur and vertebra tissues of the hypovitaminosis D kyphotic pig model |
Q34788510 | Genetic ablation of sfrp4 in mice does not affect serum phosphate homeostasis. |
Q28473286 | Genetic evidence of serum phosphate-independent functions of FGF-23 on bone |
Q37072412 | In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis |
Q37607946 | Increased osteopontin contributes to inhibition of bone mineralization in FGF23-deficient mice |
Q46264351 | Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype |
Q28480498 | Klotho lacks a vitamin D independent physiological role in glucose homeostasis, bone turnover, and steady-state PTH secretion in vivo |
Q37384718 | Latest findings in phosphate homeostasis |
Q35872803 | Long-term Fgf23 deficiency does not influence aging, glucose homeostasis, or fat metabolism in mice with a nonfunctioning vitamin D receptor |
Q36091917 | Maternal dietary vitamin D carry-over alters offspring growth, skeletal mineralisation and tissue mRNA expressions of genes related to vitamin D, calcium and phosphorus homoeostasis in swine |
Q33982618 | Mineral metabolism and aging: the fibroblast growth factor 23 enigma |
Q35441666 | Molecular basis of Klotho: from gene to function in aging |
Q37386445 | Novel mechanisms in the regulation of phosphorus homeostasis |
Q46024990 | Osteocyte Protein Expression Is Altered in Low-Turnover Osteoporosis Caused by Mutations in WNT1 and PLS3. |
Q28292402 | PPAR-gamma and aging: one link through klotho? |
Q35417067 | PTH ablation ameliorates the anomalies of Fgf23-deficient mice by suppressing the elevated vitamin D and calcium levels |
Q39122744 | Pan-FGFR inhibition leads to blockade of FGF23 signaling, soft tissue mineralization, and cardiovascular dysfunction |
Q38049170 | Phosphate handling in CKD-MBD from stage 3 to dialysis and the three strengths of lanthanum carbonate |
Q35920063 | Phosphate: known and potential roles during development and regeneration of teeth and supporting structures |
Q26777613 | Pre-treatment considerations in childhood hypertension due to chronic kidney disease |
Q36757962 | Premature aging in klotho mutant mice: cause or consequence? |
Q27325653 | Protective roles of DMP1 in high phosphate homeostasis |
Q26860470 | Regulation and function of the FGF23/klotho endocrine pathways |
Q35151453 | Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism |
Q28506271 | Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4 |
Q36988383 | Regulatory mechanisms of circulating fibroblast growth factor 23 in parathyroid diseases |
Q34479134 | Relationship between Fibroblast Growth Factor-23 and Mineral Metabolism in Chronic Kidney Disease |
Q35126790 | Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase |
Q38141236 | Review of cinacalcet hydrochloride in the management of secondary hyperparathyroidism. |
Q27000415 | Role of FGF23 in vitamin D and phosphate metabolism: implications in chronic kidney disease |
Q38745657 | Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial Cohort |
Q38152465 | Significance of the anti-aging protein Klotho |
Q26852624 | Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism |
Q36933339 | The FGF family: biology, pathophysiology and therapy |
Q34022484 | The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study. |
Q33984825 | The calcemic response to continuous parathyroid hormone (PTH)(1-34) infusion in end-stage kidney disease varies according to bone turnover: a potential role for PTH(7-84) |
Q36860289 | The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis |
Q37771349 | The phosphate regulating hormone fibroblast growth factor-23. |
Q38732752 | Therapeutic Effects of FGF23 c-tail Fc in a Murine Preclinical Model of X-Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption |
Q37914009 | Vascular and valvular calcification in chronic peritoneal dialysis patients |
Q36832673 | Vitamin D and aging: old concepts and new insights |
Q36973933 | Vitamin D and human health: lessons from vitamin D receptor null mice. |
Q37620408 | Vitamin D endocrine system and osteocytes |
Q38633152 | Vitamin D, phosphate, and vasculotoxicity. |
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