review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Christian M Hedrich | Q50271955 |
P2093 | author name string | George C Tsokos | |
P2860 | cites work | MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins | Q83586463 |
Hypomethylation of LINE-1 but not Alu in lymphocyte subsets of systemic lupus erythematosus patients | Q83876356 | ||
MicroRNA-125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus | Q84505308 | ||
Ultraviolet B exposure of peripheral blood mononuclear cells of patients with systemic lupus erythematosus inhibits DNA methylation | Q84569794 | ||
The Microprocessor complex mediates the genesis of microRNAs | Q24312976 | ||
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B | Q24564757 | ||
MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer | Q24643430 | ||
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes | Q24651802 | ||
MicroRNAs modulate hematopoietic lineage differentiation | Q27860661 | ||
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA | Q27860813 | ||
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing | Q27860903 | ||
Processing of primary microRNAs by the Microprocessor complex | Q27860986 | ||
Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus | Q56894263 | ||
Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies | Q69877518 | ||
Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus | Q79171865 | ||
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts | Q79795007 | ||
Impaired T cell protein kinase C delta activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus | Q81386368 | ||
Expression signature of microRNA-181-a reveals its crucial role in the pathogenesis of paediatric systemic lupus erythematosus | Q83563765 | ||
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex | Q28143627 | ||
DNA methylation regulates MicroRNA expression | Q28238278 | ||
Cracking the enigmatic linker histone code | Q28266573 | ||
miR-181a is an intrinsic modulator of T cell sensitivity and selection | Q28294631 | ||
The transcriptional repressor cAMP response element modulator alpha interacts with histone deacetylase 1 to repress promoter activity | Q28510260 | ||
Regulation of mRNA translation and stability by microRNAs | Q29547304 | ||
Genetic mapping in human disease | Q29614943 | ||
MicroRNA control in the immune system: basic principles | Q29618112 | ||
MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb | Q29619411 | ||
Repression of protein synthesis by miRNAs: how many mechanisms? | Q29620361 | ||
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus | Q33618909 | ||
Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus | Q33889455 | ||
A blast from the past: clearance of apoptotic cells regulates immune responses. | Q34162195 | ||
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated | Q34624154 | ||
Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis | Q34766857 | ||
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse. | Q34837305 | ||
The epigenetics of autoimmunity | Q34979322 | ||
Recent insights into the genetic basis of systemic lupus erythematosus | Q34980873 | ||
X inactivation and the complexities of silencing a sex chromosome | Q34983583 | ||
Genetics and pathogenesis of multiple sclerosis | Q35004746 | ||
Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. | Q35048475 | ||
Promoter hypomethylation results in increased expression of protein phosphatase 2A in T cells from patients with systemic lupus erythematosus | Q35143592 | ||
miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely | Q35758613 | ||
Inflammatory caspases are critical for enhanced cell death in the target tissue of Sjögren's syndrome before disease onset | Q35765504 | ||
The TNFalpha locus is altered in monocytes from patients with systemic lupus erythematosus | Q35867539 | ||
Revealing the world of RNA interference | Q35889563 | ||
A methylation rendezvous: reader meets writers | Q36837766 | ||
MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndrome | Q36841784 | ||
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation | Q37065897 | ||
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. | Q37068711 | ||
microRNAs and the immune response | Q37178538 | ||
Transcriptional regulation of IL-2 in health and autoimmunity | Q37250679 | ||
Decreased DNA methyltransferase levels contribute to abnormal gene expression in "senescent" CD4(+)CD28(-) T cells | Q37261179 | ||
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. | Q37262433 | ||
Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells | Q37314445 | ||
Epigenetic control of T-helper-cell differentiation | Q37371624 | ||
A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans | Q37452331 | ||
Epigenetic control in rheumatoid arthritis synovial fibroblasts. | Q37468471 | ||
Epigenetic histone code and autoimmunity | Q37575071 | ||
Rheumatic diseases: environment and genetics | Q37635553 | ||
Epigenetics and autoimmunity | Q37669513 | ||
Cell type-specific regulation of IL-10 expression in inflammation and disease | Q37678256 | ||
The role of defective clearance of apoptotic cells in systemic autoimmunity. | Q37739807 | ||
Interleukin-17-producing T cells in lupus | Q37769076 | ||
Rheumatoid arthritis progression mediated by activated synovial fibroblasts | Q37782498 | ||
Updating on the pathogenesis of systemic lupus erythematosus | Q37791687 | ||
Is there a link between dysregulated miRNA expression and disease? | Q37793417 | ||
Epigenetics in lupus | Q37830732 | ||
Epigenetics and autoimmunity, with special emphasis on methylation | Q37860845 | ||
miR-449a targets HDAC-1 and induces growth arrest in prostate cancer | Q39878284 | ||
A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus | Q40144366 | ||
Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients | Q40229057 | ||
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells | Q40308810 | ||
Rapid alteration of microRNA levels by histone deacetylase inhibition | Q40322140 | ||
Role of the CD6 glycoprotein in antigen-specific and autoreactive responses of cloned human T lymphocytes. | Q41177636 | ||
MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. | Q41412954 | ||
Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity | Q41959555 | ||
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail | Q41965881 | ||
B cells contribute to ischemia/reperfusion-mediated tissue injury | Q42539245 | ||
Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression | Q42640386 | ||
DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. | Q43233238 | ||
Effect of trichostatin A on human T cells resembles signaling abnormalities in T cells of patients with systemic lupus erythematosus: a new mechanism for TCR zeta chain deficiency and abnormal signaling | Q43968077 | ||
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus | Q44062277 | ||
Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression | Q45099932 | ||
IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation | Q46043693 | ||
Epigenetics and microRNAs | Q46057707 | ||
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs | Q46477434 | ||
Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis. | Q46483776 | ||
HLA DRB1*1503 allelic haplotype predominance and associated immunodysregulation in systemic lupus erythematosus | Q46681395 | ||
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex | Q46806709 | ||
Demethylation of CD40LG on the inactive X in T cells from women with lupus | Q46942094 | ||
Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis | Q47793786 | ||
Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus | Q47849248 | ||
Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells | Q47991791 | ||
Prevalence of ZAP-70, LAT, SLP-76, and DNA methyltransferase 1 expression in CD4+ T cells of patients with systemic lupus erythematosus. | Q50684216 | ||
Aberrant expression pattern of histone acetylation modifiers and mitigation of lupus by SIRT1-siRNA in MRL/lpr mice. | Q51602846 | ||
MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. | Q54374935 | ||
Overexpression of the growth arrest and DNA damage-induced 45alpha gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells. | Q54443042 | ||
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. | Q54517861 | ||
Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus. | Q54551006 | ||
Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells. | Q54615805 | ||
P433 | issue | 12 | |
P921 | main subject | lupus erythematosus | Q188297 |
systemic lupus erythematosus | Q1485 | ||
P304 | page(s) | 714-724 | |
P577 | publication date | 2011-08-30 | |
P1433 | published in | Trends in Molecular Medicine | Q15265842 |
P1476 | title | Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases | |
P478 | volume | 17 |
Q34464114 | Advances in lupus genetics and epigenetics |
Q92380687 | B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids |
Q92735504 | BCL-6 suppresses miR-142-3p/5p expression in SLE CD4+ T cells by modulating histone methylation and acetylation of the miR-142 promoter |
Q35171894 | Biomarker profiling for lupus nephritis |
Q37726675 | CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance |
Q41712674 | DNA hypomethylation of a transcription factor binding site within the promoter of a gout risk gene NRBP1 upregulates its expression by inhibition of TFAP2A binding |
Q88841098 | DNA methylation in systemic lupus erythematosus |
Q39184388 | DNA methylation of human endogenous retrovirus in systemic lupus erythematosus |
Q61959801 | Depressive Disorders: Prevalence, Costs, and Theories |
Q48238048 | Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells. |
Q34344835 | Environmental influences on systemic lupus erythematosus expression |
Q39142245 | Epigenetic Alterations in Cellular Immunity: New Insights into Autoimmune Diseases |
Q92243141 | Epigenetic Priming in Immunodeficiencies |
Q38694852 | Epigenetic alterations underlying autoimmune diseases |
Q38152825 | Epigenetic dysregulation in systemic lupus erythematosus |
Q39456337 | Epigenetic involvement in etiopathogenesis and implications in treatment of systemic lupus erythematous |
Q38206864 | Epigenetic regulation of cytokine expression in systemic lupus erythematosus with special focus on T cells |
Q38553346 | Epigenetics and Systemic Lupus Erythematosus: Unmet Needs |
Q38650522 | Epigenetics in SLE. |
Q26772330 | Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response |
Q37097751 | Epigenetics of the antibody response |
Q90319414 | Estradiol regulates the expression of CD45 splicing isoforms in lymphocytes |
Q91712007 | Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a |
Q36612326 | Ethnic differences in DNA methyltransferases expression in patients with systemic lupus erythematosus |
Q92889821 | Expression Profiling and Clinical Significance of Plasma MicroRNAs in Diabetic Nephropathy |
Q38111622 | Gene-function studies in systemic lupus erythematosus. |
Q64071574 | Genome-Wide DNA Methylation Profiles Reveal Common Epigenetic Patterns of Interferon-Related Genes in Multiple Autoimmune Diseases |
Q37089523 | High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot |
Q34647217 | Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses |
Q36236807 | Immunogenetics of systemic lupus erythematosus: A comprehensive review |
Q37581443 | MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case--control samples |
Q28943338 | Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians |
Q34549827 | MicroRNAs in lupus |
Q47972361 | Natural antisense RNAs are involved in the regulation of CD45 expression in autoimmune diseases |
Q90683634 | Peripheral nerve injury and myelination: Potential therapeutic strategies |
Q38091122 | Perspectives on epigenetic-based immune intervention for rheumatic diseases |
Q58710822 | Precision DNA demethylation ameliorates disease in lupus-prone mice |
Q36150047 | Protein kinase Cδ oxidation contributes to ERK inactivation in lupus T cells |
Q37168446 | Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodeling |
Q37350170 | Sex differences in the expression of lupus-associated miRNAs in splenocytes from lupus-prone NZB/WF1 mice |
Q27010090 | Small molecules in the treatment of systemic lupus erythematosus |
Q34217935 | Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling |
Q37602111 | Targeted DNA methylation analysis by high throughput sequencing in porcine peri-attachment embryos |
Q64102294 | The Emerging Epigenetic Role of CD8+T Cells in Autoimmune Diseases: A Systematic Review |
Q90705230 | The Pathogenic Role of Dysregulated Epigenetic Modifications in Autoimmune Diseases |
Q92106859 | The Role of Epigenetics in Autoimmune/Inflammatory Disease |
Q35986953 | The Upregulation of Genomic Imprinted DLK1-Dio3 miRNAs in Murine Lupus Is Associated with Global DNA Hypomethylation |
Q38085206 | The applied basic research of systemic lupus erythematosus based on the biological omics. |
Q37048453 | The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway |
Q35723616 | The real culprit in systemic lupus erythematosus: abnormal epigenetic regulation |
Q28389137 | The role of epigenetic mechanisms and processes in autoimmune disorders |
Q92309432 | Transcriptome Analysis and Emerging Driver Identification of CD8+ T Cells in Patients with Vitiligo |
Q41228881 | Translating epigenetics into clinic: focus on lupus |
Q38193368 | Unmet needs in autoimmunity and potential new tools |
Q36339914 | cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus. |
Q37511786 | cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells |
Q37477836 | cAMP responsive element modulator: a critical regulator of cytokine production |
Q36466592 | cAMP-responsive element modulator α (CREMα) contributes to decreased Notch-1 expression in T cells from patients with active systemic lupus erythematosus (SLE). |
Q35763036 | cAMP-responsive element modulator α (CREMα) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE). |
Q36977367 | miR-150 promotes renal fibrosis in lupus nephritis by downregulating SOCS1 |
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