HIV-specific gag responses in early infancy correlate with clinical outcome and inversely with viral load

scientific article published on 12 May 2011

HIV-specific gag responses in early infancy correlate with clinical outcome and inversely with viral load is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1089/AID.2011.0081
P932PMC publication ID3227240
P698PubMed publication ID21476948

P50authorGregory D HusseyQ77719216
Cheryl L DayQ85416307
W Henry BoomQ86906278
Nazma MansoorQ117261269
Gilla KaplanQ60908373
Willem Albert HanekomQ71104683
P2093author name stringTony Hawkridge
E Jane Hughes
Marwou De Kock
Bongeka Nqoko
P2860cites workNatural history of vertically acquired human immunodeficiency virus-1 infection. The European Collaborative StudyQ72832300
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infectionQ24645815
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndromeQ24648628
Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremiaQ28254584
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsQ29616205
HIV-1 infection in infants severely impairs the immune response induced by Bacille Calmette-Guérin vaccineQ33627000
Longitudinal assessment of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon responses during the first year of life in HIV-1-infected infantsQ33843438
Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infectionQ33869806
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1Q34545760
Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expressionQ35904453
Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infantsQ36315692
Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral loadQ37009811
Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containmentQ37271461
Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptidesQ37422520
HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognitionQ41966337
Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytesQ43163152
Viral load and disease progression in infants infected with human immunodeficiency virus type 1. Women and Infants Transmission Study GroupQ44142380
Natural history of human immunodeficiency virus type 1 infection in children: a five-year prospective study in Rwanda. Mother-to-Child HIV-1 Transmission Study GroupQ45746506
Age- and time-related changes in extracellular viral load in children vertically infected by human immunodeficiency virusQ45765734
HIV-specific CD8+ T cell function in children with vertically acquired HIV-1 infection is critically influenced by age and the state of the CD4+ T cell compartmentQ46498993
CD8+ T-cell responses to different HIV proteins have discordant associations with viral loadQ57259602
Differential Immunogenicity of HIV‐1 Clade C Proteins in Eliciting CD8+and CD4+Cell ResponsesQ57259616
P433issue12
P921main subjectviral loadQ2528140
P304page(s)1311-1316
P577publication date2011-05-12
P1433published inAIDS Research and Human RetrovirusesQ4651880
P1476titleHIV-specific gag responses in early infancy correlate with clinical outcome and inversely with viral load
P478volume27

Reverse relations

cites work (P2860)
Q34033051Immunity to HIV in Early Life
Q33813145Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles
Q38037339The impact of differential antiviral immunity in children and adults