Short-term use of antiepileptic drugs is neurotoxic to the immature brain

scientific article published on April 2015

Short-term use of antiepileptic drugs is neurotoxic to the immature brain is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4103/1673-5374.155434
P932PMC publication ID4424753
P698PubMed publication ID26170821

P2093author name stringLin Yang
Yu Liu
Dan Li
Shao-Ping Huang
Xue-Ying Wang
P2860cites workGenetic enhancement of learning and memory in miceQ22010371
Antiepileptic drugs and apoptotic neurodegeneration in the developing brainQ24538604
Identification of a phosphorylation site for calcium/calmodulindependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptorQ28298139
Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memoryQ28588695
Learning induces long-term potentiation in the hippocampusQ29619482
Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficitsQ30310499
Safety and efficacy of topiramate in neonates with hypoxic ischemic encephalopathy treated with hypothermia (NeoNATI)Q30462209
NMDA receptor subunits: diversity, development and diseaseQ33950711
Convulsive status epilepticus and health-related quality of life in children with epilepsyQ34112963
Phenobarbital for the treatment of epilepsy in the 21st century: a critical reviewQ34343308
Late cognitive effects of early treatment with phenobarbitalQ34504315
Newer anticonvulsants: dosing strategies and cognition in treating patients with mood disorders and epilepsy.Q35189346
Neonatal exposure to antiepileptic drugs disrupts striatal synaptic developmentQ36170106
Antiepileptic drugs and the developing brainQ36359030
New anticonvulsants--new adverse effectsQ36458071
Topiramate: Effects on cognition in patients with epilepsy, migraine headache and obesityQ36999739
Metabotropic glutamate receptors: synaptic modulators and therapeutic targets for neurologic diseaseQ37112406
AMPARs and synaptic plasticity: the last 25 yearsQ38158723
Developmental neurotoxicity and anticonvulsant drugs: a possible link.Q38209905
Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasiasQ40222907
Evaluation of neurotoxic and neuroprotective pathways affected by antiepileptic drugs in cultured hippocampal neurons.Q42445199
Effect of behavioral training on learning and memory capacity and changes of hippocampal NR2B and GluR1 expressions in FGR offspring ratsQ43083877
Structure and different conformational states of native AMPA receptor complexesQ45250189
Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitalsQ46139293
Chronic application of topiramate and carbamazepine differentially affects the EEG and penicillin-induced epileptiform activity in ratsQ46165220
Neonatal seizures: multicenter variability in current treatment practicesQ46424372
Comparison of the effects of anticonvulsant drugs with diverse mechanisms of action in the formalin test in ratsQ46460599
Off-label use of antiepileptic drugs for the treatment of neonatal seizuresQ46474491
Expression of Hsp70 and Caspase-3 in rabbits after severe traumatic brain injury.Q48277135
Certain secondary antiepileptic drugs can rescue hippocampal injury following a critical growth period despite poor anticonvulsant activity and cognitive deficitsQ48950669
Neurobehavioral comorbidities in children with active epilepsy: a population-based studyQ50306785
The effects of valproate exposure in utero on behavior and the need for educational support in school-aged children.Q51911328
Long-term consequences of early postnatal seizures on hippocampal learning and plasticity.Q52025073
Topiramate as an add-on antiepileptic drug in treating refractory canine idiopathic epilepsyQ62083152
Summary proceedings from the neurology group on neonatal seizuresQ79733535
Efficacy of topiramate as add-on therapy in two different types of progressive myoclonic epilepsyQ87185920
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectneurotoxicityQ3338704
P304page(s)599-604
P577publication date2015-04-01
P1433published inNeural Regeneration ResearchQ15710164
P1476titleShort-term use of antiepileptic drugs is neurotoxic to the immature brain
P478volume10

Reverse relations

Q48009977The effects of adding prophylactic phenobarbital to therapeutic hypothermia in the term-equivalent hypoxic-ischemic rat.cites workP2860

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