The queuine micronutrient: charting a course from microbe to man.

scientific article published on 15 April 2015

The queuine micronutrient: charting a course from microbe to man. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3390/NU7042897
P932PMC publication ID4425180
P698PubMed publication ID25884661
P5875ResearchGate publication ID275259870

P50authorVincent P. KellyQ73804685
P2093author name stringClaire Fergus
Dominic Barnes
Mashael A Alqasem
P2860cites workRNA processing in microinjected Xenopus oocytes. Sequential addition of base modifications in the spliced transfer RNA.Q48410881
Isoaccepting transfer ribonucleic acids in liver and brain of young and old BC3F1 miceQ48711252
Changes in rat liver transfer RNA following growth hormone administration and in regenerating liverQ48894988
Enzymatic formation of modified nucleosides in tRNA: dependence on tRNA architectureQ49022049
Relationship of queuine-lacking transfer RNA to the grade of malignancy in human leukemias and lymphomasQ49280153
Characterization of cDNA encoding the human tRNA-guanine transglycosylase (TGT) catalytic subunitQ24290933
Cloning and characterization of cDNA encoding the rabbit tRNA-guanine transglycosylase 60-kilodalton subunitQ24319128
Queuosine modification of the wobble base in tRNAHis influences 'in vivo' decoding propertiesQ24555808
Enzymatic synthesis of Q*nucleoside containing mannose in the anticodon of tRNA: isolation of a novel mannosyltransferase from a cell-free extract of rat liverQ24613497
Mitochondria and the autophagy-inflammation-cell death axis in organismal agingQ26995343
Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification EnzymeQ27641144
An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coliQ27641818
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediateQ27641936
Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug designQ27642266
Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate bindingQ27644905
Crystal structure of glutamyl-queuosine tRNAAsp synthetase complexed with L-glutamate: structural elements mediating tRNA-independent activation of glutamate and glutamylation of tRNAAsp anticodonQ27651045
An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interactionQ27656669
Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as InhibitorQ27678289
Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophileQ27734193
Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structureQ28118413
Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidationQ28235401
A riboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domainQ28294896
Ubiquitin-specific protease 14 expression in colorectal cancer is associated with liver and lymph node metastasesQ28296212
Transfer ribonucleic acid guanine transglycosylase isolated from rat liverQ28580269
Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylaseQ28594211
Queuine, The Q-Containing tRNAs and the Enzymes Responsible for Their FormationQ29391758
Possible anticodon sequences of tRNAHis, tRNAAsn, and tRNAAsp from Escherichia coli. Universal presence of nucleoside O in the first position of the anticodons of these transfer ribonucleic acidQ29540613
tRNA biology charges to the frontQ29616318
Is meconium from healthy newborns actually sterile?Q30841114
Codon usage in twelve species of DrosophilaQ33305695
Site-directed in vitro replacement of nucleosides in the anticodon loop of tRNA: application to the study of structural requirements for queuine insertase activityQ33933659
Queuosine modification of tRNA: a case for convergent evolutionQ33955118
Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA.Q33965482
Decoding the genome: a modified viewQ33975049
Speeding with control: codon usage, tRNAs, and ribosomesQ34033290
Plant, animal, and fungal micronutrient queuosine is salvaged by members of the DUF2419 protein familyQ34061163
Structural, functional, and taxonomic diversity of three preQ1 riboswitch classes.Q34091541
Three-dimensional structure of hyper-modified nucleoside Q located in the wobbling position of tRNAQ34193273
Studies with a homogeneous enzyme from rabbit erythrocytes catalyzing the insertion of guanine into tRNA.Q34281882
A truncated aminoacyl-tRNA synthetase modifies RNA.Q34335615
A minimal estimate for the gene content of the last universal common ancestor--exobiology from a terrestrial perspectiveQ34564414
Queuosine biosynthesis is required for sinorhizobium meliloti-induced cytoskeletal modifications on HeLa Cells and symbiosis with Medicago truncatulaQ34586583
A nutrient-driven tRNA modification alters translational fidelity and genome-wide protein coding across an animal genusQ34662812
Involvement of protein kinase C in the control of tRNA modification with queuine in HeLa cellsQ34760599
Activation of transfer RNA-guanine ribosyltransferase by protein kinase CQ34760660
Enzymatic replacement in vitro of the first anticodon base of yeast tRNAAsp: application to the study of tRNA maturation in vivo, after microinjection into frog oocytesQ35516050
The role of queuine in the aminoacylation of mammalian aspartate transfer RNAsQ35678293
Presence of queuine in Drosophila melanogaster: correlation of free pool with queuosine content of tRNA and effect of mutations in pteridine metabolismQ35710500
tRNA isoacceptor preference prior to retrovirus Gag-Pol junction links primer selection and viral translationQ35857321
Site-specific modification of Shigella flexneri virF mRNA by tRNA-guanine transglycosylase in vitroQ35945409
vacC, a virulence-associated chromosomal locus of Shigella flexneri, is homologous to tgt, a gene encoding tRNA-guanine transglycosylase (Tgt) of Escherichia coli K-12Q35967502
Detection of unique tRNA species in tumor tissues by Escherichia coli guanine insertion enzymeQ35989905
Correlation between the presence of tRNAHisGUGand the erythropoietic function in foetal sheep liverQ36176712
Isolation of mammalian tRNAAspand tRNATyrby lectin-Sepharose affinity column chromatographyQ36179888
Relationship between a tumor promoter-induced decrease in queuine modification of transfer RNA in normal human cells and the expression of an altered cell phenotypeQ70948123
Modulation of queuine uptake and incorporation into tRNA by protein kinase C and protein phosphataseQ71078285
Altered urinary excretion of pteridines in neoplastic disease. Determination of biopterin, neopterin, xanthopterin, and pterinQ71263452
Substrate and inhibitor specificity of tRNA-guanine ribosyltransferaseQ71269930
Specific changes in lactate levels, lactate dehydrogenase patterns and cytochrome b559 in Dictyostelium discoideum caused by queuineQ71273106
Altered growth properties of normal human cells induced by phorbol 12,13-didecanoateQ71355331
Effect of diet on the queuosine family of tRNAs of germ-free miceQ71508342
Administration of queuine to mice relieves modified nucleoside queuosine deficiency in Ehrlich ascites tumor tRNAQ71523137
Administration of exogenous queuine is essential for the biosynthesis of the queuosine-containing transfer RNAs in the mouseQ71574789
Isolation and characterization of an Escherichia coli mutant lacking tRNA-guanine transglycosylase. Function and biosynthesis of queuosine in tRNAQ71601854
Salvage of the nucleic acid base queuine from queuine-containing TRNA by animal cellsQ71967591
Deficiency of queuine, a highly modified purine base, in transfer RNAs from primary and metastatic ovarian malignant tumors in womenQ72092518
Modification of guanine to queuine in transfer RNAs during development and agingQ72635702
Effects of a diet deficient in tyrosine and queuine on germfree miceQ73031298
Slight sequence variations of a common fold explain the substrate specificities of tRNA-guanine transglycosylases from the three kingdomsQ73879406
Suppression of mutations in mitochondrial DNA by tRNAs imported from the cytoplasmQ74316460
tRNA-guanine transglycosylase from Escherichia coli: recognition of full-length 'queuine-cognate' tRNAsQ77135168
Formation and fate of tyrosine. Intracellular partitioning of newly synthesized tyrosine in mammalian liverQ77696617
Hypomodification of transfer RNA in cancer with respect to queuosineQ79370499
tRNA-guanine transglycosylase from bovine liver. Purification of the enzyme to homogeneity and biochemical characterization.Q52208359
Queuine metabolism and cadmium toxicity in Drosophila melanogaster.Q52447184
Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus.Q52470540
Evolution of the Adh locus in the Drosophila willistoni group: the loss of an intron, and shift in codon usage.Q52544857
Synonymous substitution rates in Drosophila: mitochondrial versus nuclear genes.Q52559181
The effect of queuosine on tRNA structure and function.Q52911673
Specific lack of the hypermodified nucleoside, queuosine, in hepatoma mitochondrial aspartate transfer RNA and its possible biological significance.Q53553781
Studies on polynucleotides. XCI. Yeast methionine transfer ribonucleic acid: purification, properties, and terminal nucleotide sequences.Q53721165
Investigating the prevalence of queuine in Escherichia coli RNA via incorporation of the tritium-labeled precursor, preQ(1).Q54331841
tRNA-guanine transglycosylase from Escherichia coli: recognition of dimeric, unmodified tRNA(Tyr).Q54645958
Q-modification of tRNAs in human brain tumors.Q55481793
Amber Suppression: a Nucleotide Change in the Anticodon of a Tyrosine Transfer RNAQ59085994
Nucleotide Sequence of Escherichia coli Tyrosine Transfer Ribonucleic AcidQ60020184
The nutrient factor queuine protects HeLa cells from hypoxic stress and improves metabolic adaptation to oxygen availability.Q64993873
High turnover rate of transfer RNA in tumor tissueQ67598938
Letter: The structure of Q* nucleoside isolated from rabbit liver transfer ribonucleic acidQ67779344
Relationship of the queuine content of transfer ribonucleic acids to histopathological grading and survival in human lung cancerQ68026574
Possible involvement of queuine in oxidative metabolismQ68088068
The deazaguanine-derivative, queuine, affects cell proliferation, protein phosphorylation and the expression of the proto oncogenes c-fos and c-myc in HeLa cellsQ68340146
Queuine modulates growth of HeLa cells depending on oxygen availabilityQ68668601
Possible involvement of queuine in control mechanisms of protein synthesis and protein phosphorylation in eukaryotesQ68871710
Guanylation of Transfer Ribonucleic Acid by a Cell-free Lysate of Rabbit ReticulocytesQ69604197
Inhibition of queuine uptake in cultured human fibroblasts by phorbol-12,13-didecanoateQ70058031
Queuine salvage in mammalian cells. Evidence that queuine is generated from queuosine 5'-phosphateQ70185270
Queuine, a modified base incorporated posttranscriptionally into eukaryotic transfer RNA: wide distribution in natureQ70298147
Inhibition of queuine uptake in diploid human fibroblasts by phorbol-12,13-didecanoate. Requirement for a factor derived from early passage cellsQ70305980
Why is tumor tRNA hypomodified with respect to Q nucleoside?Q70432278
Dictyostelium discoideum: a useful model system to evaluate the function of queuine and of the Q-family of tRNAsQ70511809
Purification and properties of guanine, queuine-tRNA transglycosylase from wheat germQ70515021
Changes in Amount of Hypo‐Modified tRNA Having Guanine in Place of Queuine during Erythroid Differentiation of Murine Erythroleukemia CellsQ70792841
Evidence that the nucleic acid base queuine is incorporated intact into tRNA by animal cellsQ70865874
Specific replacement of Q base in the anticodon of tRNA by guanine catalyzed by a cell-free extract of rabbit reticulocytesQ36200318
A doubtful relationship between tyrosine tRNA and suppression of the vermilion mutant in DrosophilaQ36203118
Novel salvage of queuine from queuosine and absence of queuine synthesis in Chlorella pyrenoidosa and Chlamydomonas reinhardtiiQ36224618
Mechanism and substrate specificity of tRNA-guanine transglycosylases (TGTs): tRNA-modifying enzymes from the three different kingdoms of life share a common catalytic mechanism.Q36277356
PROTEIN SYNTHESIS IN ERYTHROID CELLS, I. RETICULOCYTE RIBOSOMES ACTIVE IN STIMULATING AMINO ACID INCORPORATION.Q36397933
Mammalian mitochondria have the innate ability to import tRNAs by a mechanism distinct from protein importQ36756988
A factor in serum and amniotic fluid is a substrate for the tRNA-modifying enzyme tRNA-guanine transferaseQ37336236
Identification of the rate-determining step of tRNA-guanine transglycosylase from Escherichia coliQ37464111
Emerging role of damage-associated molecular patterns derived from mitochondria in inflammationQ37844960
Biosynthesis and function of tRNA modifications in ArchaeaQ37862455
Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseasesQ37930666
Biosynthesis and function of posttranscriptional modifications of transfer RNAsQ38035925
Mitochondrial disorders as windows into an ancient organelleQ38059778
Mitochondrial dynamics in neurodegenerationQ38060435
The Escherichia coli tRNA-guanine transglycosylase can recognize and modify DNA.Q38293680
Isolation and characterization of a guanine insertion enzyme, a specific tRNA transglycosylase, from Escherichia coliQ39655466
Alteration of the Q family of transfer RNAs in adult Drosophila melanogaster as a function of age, nutrition, and genotypeQ39689592
Possible involvement of queuine in regulation of cell proliferationQ40040564
Structure, biosynthesis, and function of queuosine in transfer RNA.Q40208199
The function of the histidine tRNA isoaccepting species in hemoglobin synthesisQ40388404
C to U editing and modifications during the maturation of the mitochondrial tRNA(Asp) in marsupialsQ40395606
Transfer ribonucleic acids from eleven immunoglobulin-secreting mouse plasmacytomas Constant and variable chromatographic profiles compared with the myeloma protein sequencesQ40421911
Specific changes in Q-ribonucleoside containing transfer RNA species during Friend leukemia cell erythroid differentiation.Q40481908
Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cellsQ40594085
Determination of queuosine modification system deficiencies in cultured human cellsQ40930180
Defective transfer RNA-queuine modification in C3H10T1/2 murine fibroblasts transfected with oncogenic ras.Q41235722
Altered queuine modification of transfer RNA involved in the differentiation of human K562 erythroleukemia cells in the presence of distinct differentiation inducersQ41474336
Modulation of mammalian cell proliferation by a modified tRNA base of bacterial originQ41508253
Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell lineQ41614356
Alterations in cell tetrahydrobiopterin levels may regulate queuine hypomodification of tRNA during differentiation of murine erythroleukemia cellsQ41675932
Differential heterocyclic substrate recognition by, and pteridine inhibition of E. coli and human tRNA-guanine transglycosylasesQ41955456
Queuosine metabolism: possible relation to B-cell activation by C8 derivatives of guanosineQ42225992
Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 proteinQ42537947
Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylasesQ42714223
tRNA-guanine transglycosylase from Escherichia coli: recognition of noncognate-cognate chimeric tRNA and discovery of a novel recognition site within the TpsiC arm of tRNA(Phe).Q43206593
Guanylation of transfer RNA by rabbit reticulocytesQ43448312
Enzymatic formation of queuosine and of glycosyl queuosine in yeast tRNAs microinjected into Xenopus laevis oocytes. The effect of the anticodon loop sequenceQ43463310
An unexpected absence of queuosine modification in the tRNAs of an Escherichia coli B strainQ44248181
A simple tandem repeat polymorphism is present in the eighth intron of FLJ12960, a possible queuine salvage enzyme geneQ44645365
Analysis of a shift in codon usage in Drosophila.Q44791503
Interferon induced inhibition of queuine uptake in cultured human fibroblastsQ44923287
Protein kinase C modulation of queuine uptake in cultured human fibroblastsQ44961992
Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancerQ44972529
Partial purification and properties of the reticulocyte guanylating enzymeQ45159238
Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental blockQ45375950
Modulation of lactate dehydrogenase isozymes by modified base queuine.Q46712004
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectheterocyclic compoundQ193430
physiological phenomenonQ66615932
P304page(s)2897-2929
P577publication date2015-04-15
P1433published inNutrientsQ7070485
P1476titleThe queuine micronutrient: charting a course from microbe to man.
P478volume7

Reverse relations

cites work (P2860)
Q37153824Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system
Q37729420Cross-Talk between Dnmt2-Dependent tRNA Methylation and Queuosine Modification.
Q45839282Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways.
Q95660323Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion
Q93086348Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens
Q41830843Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine
Q92879629Emergence of a "Cyclosome" in a Primitive Network Capable of Building "Infinite" Proteins
Q40531149Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification.
Q26764834From Prebiotics to Probiotics: The Evolution and Functions of tRNA Modifications
Q28070578Genome recoding by tRNA modifications
Q48304481Identification of a Novel Epoxyqueuosine Reductase Family by Comparative Genomics
Q33558399In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis
Q62415130Matching tRNA modifications in humans to their known and predicted enzymes
Q38845904Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation.
Q29391512Mg2+Shifts Ligand-Mediated Folding of a Riboswitch from Induced-Fit to Conformational Selection
Q91638492Micronutrient Requirements and Sharing Capabilities of the Human Gut Microbiome
Q57465773Prolonging healthy aging: Longevity vitamins and proteins
Q45887615Protein folding and tRNA biology
Q90663227Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells
Q64230137Queuine links translational control in eukaryotes to a micronutrient from bacteria
Q57187710Queuing up the ribosome: nutrition and the microbiome control protein synthesis
Q60761605Queuosine modification protects cognate tRNAs against ribonuclease cleavage
Q57267520Queuosine-modified tRNAs confer nutritional control of protein translation
Q28078569Rapid and dynamic transcriptome regulation by RNA editing and RNA modifications
Q38951451Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour
Q55281880Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine.
Q37729417The Escherichia coli COG1738 Member YhhQ Is Involved in 7-Cyanodeazaguanine (preQ₀) Transport
Q64084981Transcriptome and Proteome Response of Tick Vector to Infection
Q50543366[Involvement of gut bacteria in appetite control].
Q90394256tRNA Queuosine Modification Enzyme Modulates the Growth and Microbiome Recruitment to Breast Tumors
Q60915603tRNA-Derived Small RNAs: Biogenesis, Modification, Function and Potential Impact on Human Disease Development

Search more.