| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PLoSO...628430C |
| P356 | DOI | 10.1371/JOURNAL.PONE.0028430 |
| P932 | PMC publication ID | 3228772 |
| P698 | PubMed publication ID | 22145044 |
| P5875 | ResearchGate publication ID | 51856041 |
| P50 | author | Patricia Ernst | Q55155210 |
| P2093 | author name string | Nancy A Speck | |
| Michael J Chen | |||
| Maria Elena De Obaldia | |||
| James K Mangan | |||
| Xiongwei Cai | |||
| Justin J Gaudet | |||
| Zaw Oo | |||
| P2860 | cites work | NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells | Q24304091 |
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| Runx1 modulates developmental, but not injury-driven, hair follicle stem cell activation. | Q34747058 | ||
| Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype. | Q34753320 | ||
| Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect | Q35052404 | ||
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| Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter | Q37347018 | ||
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| Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors | Q39997748 | ||
| Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells | Q40251801 | ||
| RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress | Q40708275 | ||
| AML1 stimulates G1 to S progression via its transactivation domain | Q40722480 | ||
| Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations. | Q40871580 | ||
| Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins | Q40874612 | ||
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| Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system. | Q42474718 | ||
| RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53. | Q42829128 | ||
| Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells | Q42938783 | ||
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| Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells | Q45085155 | ||
| AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations. | Q46111829 | ||
| High frequency of AML1/RUNX1 point mutations in radiation-associated myelodysplastic syndrome around Semipalatinsk nuclear test site | Q46270639 | ||
| CBFbeta-SMMHC slows proliferation of primary murine and human myeloid progenitors | Q46426188 | ||
| The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia | Q50335773 | ||
| Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia. | Q50649768 | ||
| RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation. | Q51771337 | ||
| Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing. | Q52085270 | ||
| Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. | Q52111650 | ||
| Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells | Q57362319 | ||
| TEL-AML1 Corrupts Hematopoietic Stem Cells to Persist in the Bone Marrow and Initiate Leukemia | Q57514984 | ||
| Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1 | Q57740696 | ||
| PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention | Q59067116 | ||
| Hematopoietic stem cells found in lineage-positive subsets in the bone marrow of 5-fluorouracil-treated mice | Q70802975 | ||
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| CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells | Q73743373 | ||
| Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias | Q74587955 | ||
| Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia | Q78410473 | ||
| X-ray sensitivity and DNA synthesis in synchronous populations of HeLa cells | Q79630305 | ||
| Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult | Q81152616 | ||
| RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis | Q82837979 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e28430 | |
| P577 | publication date | 2011-12-01 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Runx1 loss minimally impacts long-term hematopoietic stem cells | |
| P478 | volume | 6 |
| Q37541710 | A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation |
| Q38101285 | A role for RUNX1 in hematopoiesis and myeloid leukemia. |
| Q47284616 | A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells |
| Q57580487 | Analysis of Runx1 Using Induced Gene Ablation Reveals Its Essential Role in Pre-liver HSC Development and Limitations of an In Vivo Approach |
| Q92509243 | Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium |
| Q64008558 | Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation |
| Q37124583 | Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells |
| Q34905970 | Ectopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis |
| Q36395604 | Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome |
| Q37496355 | Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations. |
| Q34284318 | Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice. |
| Q40293334 | Internal tandem duplication of FLT3 deregulates proliferation and differentiation and confers resistance to the FLT3 inhibitor AC220 by Up-regulating RUNX1 expression in hematopoietic cells |
| Q33441740 | Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors |
| Q33917204 | NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis |
| Q89595398 | Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells |
| Q50074717 | RUNX1 Mutations in Inherited and Sporadic Leukemia |
| Q89634518 | RUNX1 Mutations in the Leukemic Progression of Severe Congenital Neutropenia |
| Q40329715 | RUNX1 cooperates with FLT3-ITD to induce leukemia. |
| Q34089154 | RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement |
| Q35903884 | RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis |
| Q41941467 | Resistance in the Ribosome: RUNX1, pre-LSCs, and HSPCs |
| Q39181407 | Runx Family Genes in Tissue Stem Cell Dynamics |
| Q42428228 | Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells |
| Q36442414 | Runx1 Phosphorylation by Src Increases Trans-activation via Augmented Stability, Reduced Histone Deacetylase (HDAC) Binding, and Increased DNA Affinity, and Activated Runx1 Favors Granulopoiesis |
| Q33585261 | Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder. |
| Q35995201 | Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis |
| Q90623565 | Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling |
| Q37662400 | Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia |
| Q34318485 | The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells |
| Q41862653 | The transcriptional programme controlled by Runx1 during early embryonic blood development |
| Q27023005 | Transcription factor-mediated reprogramming toward hematopoietic stem cells |
| Q42248791 | Tyrosyl phosphorylation toggles a Runx1 switch |
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