Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation

scientific article published on 25 January 2007

Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI28844
P932PMC publication ID1770945
P698PubMed publication ID17256058

P50authorRaymond A SobelQ87841746
Miguel P. SoaresQ41502664
Sílvia CardosoQ55475865
Teresa F PaisQ58492732
P2093author name stringLawrence Steinman
Paulo Fontoura
Peggy P Ho
Andreia Cunha
Lowen Y Lee
Angelo A Chora
P2860cites workOxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiencyQ22008645
The role of heme oxygenase-1 promoter polymorphisms in human diseaseQ28284902
Multiple sclerosisQ29616022
Points of control in inflammationQ29620319
Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplantsQ32133832
Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null miceQ33849603
Expression of heme oxygenase-1 can determine cardiac xenograft survivalQ59655267
Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune EncephalomyelitisQ61709597
A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoireQ63535316
Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expressionQ71066478
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic miceQ71641038
Heme oxygenase-1 in lesions of rat experimental autoimmune encephalomyelitis and neuritisQ73056362
Multiple sclerosis: a two-stage diseaseQ74433993
Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitisQ78404404
Multiple sclerosisQ79880889
Immunology of multiple sclerosisQ81531267
Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.Q34032006
The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant propertiesQ34203933
New concepts in the immunopathogenesis of multiple sclerosisQ34609924
Different faces of the heme-heme oxygenase system in inflammationQ35180318
Heme oxygenase-1: unleashing the protective properties of hemeQ35196426
Heme oxygenase expression in human central nervous system disordersQ35950661
An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cellsQ36103387
Virtues and pitfalls of EAE for the development of therapies for multiple sclerosisQ36254088
Regulation of MHC class II gene expression by the class II transactivatorQ36274925
CO as a cellular signaling moleculeQ36364694
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis.Q36368967
Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitisQ36401257
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenaseQ36475899
Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain.Q36506367
Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of ironQ37381529
Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis.Q40489284
The role of the MHC class II transactivator in class II expression and antigen presentation by astrocytes and in susceptibility to central nervous system autoimmune diseaseQ40684804
Exacerbations of multiple sclerosis in patients treated with gamma interferonQ40797798
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathwayQ40890343
Haem oxygenase-1 prevents cell death by regulating cellular iron.Q40918541
IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice.Q41005196
Protective genes expressed in endothelial cells: a regulatory response to injuryQ41632984
Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirusQ41736276
Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitisQ42753284
Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosisQ43247720
Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitisQ43660865
Heme oxygenase-1 in SJL mice with experimental allergic encephalomyelitisQ44554584
Biliverdin, a natural product of heme catabolism, induces tolerance to cardiac allograftsQ44772668
Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 productionQ44832264
A key role for heme oxygenase-1 in nitric oxide resistance in murine motor neurons and gliaQ45135792
Experimental autoimmune encephalomyelitis repressed by microglial paralysis.Q45235066
Microglial cell activation and proliferation precedes the onset of CNS autoimmunityQ46549845
Bilirubin: a natural inhibitor of vascular smooth muscle cell proliferationQ46640973
Brain macrophage activation in murine cerebral malaria precedes accumulation of leukocytes and CD8+ T cell proliferationQ48008284
Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrationsQ48106423
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.Q49014751
TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.Q54150165
Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expressionQ56975206
Heme oxygenase-1 modulates the allo-immune response by promoting activation-induced cell death of T cellsQ57202262
Heme oxygenase-1 is not required for mouse regulatory T cell development and functionQ59655037
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcarbon monoxideQ2025
neuronitisQ17157137
P304page(s)438-447
P577publication date2007-01-25
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleHeme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation
P478volume117

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