In siblings with similar genetic susceptibility for inflammatory bowel disease, smokers tend to develop Crohn's disease and non-smokers develop ulcerative colitis

scientific article published on July 2002

In siblings with similar genetic susceptibility for inflammatory bowel disease, smokers tend to develop Crohn's disease and non-smokers develop ulcerative colitis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1136/GUT.51.1.21
P932PMC publication ID1773287
P698PubMed publication ID12077086
P5875ResearchGate publication ID11298114

P2093author name stringI Bjarnason
A J Macpherson
J C W Lee
J E Lennard Jones
S Bridger
P2860cites workA frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
A meta-analysis of the role of smoking in inflammatory bowel diseaseQ28262131
Mapping of a susceptibility locus for Crohn's disease on chromosome 16Q28275042
Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBD1) to ulcerative colitisQ33680361
Recent developments in the immunology of inflammatory bowel diseaseQ33815932
Role of cytokines in the pathogenesis of inflammatory bowel diseaseQ33896046
Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel diseaseQ33902126
Linkage of inflammatory bowel disease to human chromosome 6pQ34146351
Linkage and association between inflammatory bowel disease and a locus on chromosome 12Q34386242
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohortQ34389150
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility lociQ34390578
Anticipation in familial Crohn's disease.Q35349176
Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analysesQ35354820
Cigarette smoking and rheumatoid arthritis severityQ35547371
Immune and inflammatory function in cigarette smokersQ36164981
Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.Q36493604
Inflammatory bowel disease (1)Q37278321
Risk factors for early postoperative recurrence of Crohn's diseaseQ40849749
Smoking habits and recurrence in Crohn's diseaseQ41041037
Smoking and immunity: an additional player in the mosaic of autoimmunityQ41331719
Tobacco and smoking: environmental factors that modify the host response (immune system) and have an impact on periodontal healthQ41657057
Genetic analysis in Italian families with inflammatory bowel disease supports linkage to the IBD1 locus--a GISC study.Q41684197
A genome-wide search identifies potential new susceptibility loci for Crohn's diseaseQ41704778
High-density genome scan in Crohn disease shows confirmed linkage to chromosome 14q11-12Q41728079
Smoking and its effects on early-onset periodontitisQ45081341
Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16.Q46798999
Inflammatory bowel disease: etiology and pathogenesisQ47899867
Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitisQ48059532
Validity of cigarette smoking habits in three epidemiologic studies in Utah.Q54784916
American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12Q57278657
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populationsQ57436454
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12Q59418582
Cigarette smoke aggravates experimental colitis in ratsQ61892547
Effects of tobacco glycoprotein (TGP) on the immune system. II. TGP stimulates the proliferation of human T cells and the differentiation of human B cells into Ig secreting cellsQ68091400
Cigarette smoking and inflammatory bowel diseaseQ69058156
Smoking and risk of Graves' diseaseQ70528232
Affected-sib-pair interval mapping and exclusion for complex genetic traits: sampling considerationsQ71300195
Inflammatory bowel disease in 67 families each with three or more affected first-degree relativesQ71466282
Susceptibility loci in inflammatory bowel diseaseQ71849366
The validity of self-reported smoking: a review and meta-analysisQ72029301
Involvement of neutrophils and free radicals in the potentiating effects of passive cigarette smoking on inflammatory bowel disease in ratsQ73026342
Analysis of Australian Crohn's disease pedigrees refines the localization for susceptibility to inflammatory bowel disease on chromosome 16Q77924848
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectCrohn's diseaseQ1472
siblingQ31184
inflammatory bowel diseasesQ917447
P304page(s)21-25
P577publication date2002-07-01
P1433published inGutQ5621669
P1476titleIn siblings with similar genetic susceptibility for inflammatory bowel disease, smokers tend to develop Crohn's disease and non-smokers develop ulcerative colitis
P478volume51

Reverse relations

cites work (P2860)
Q24678661A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon
Q36887143A prospective study of cigarette smoking and the risk of inflammatory bowel disease in women
Q34562065A review of juvenile polyposis syndrome
Q43544849Are there any differences in phenotype or disease course between familial and sporadic cases of inflammatory bowel disease? Results of a population-based follow-up study
Q38979037Childhood Maltreatment Is Associated with Ulcerative Colitis but Not Crohn's Disease: Findings from a Population-based Study
Q34023974Cigarette smoke extract (CSE) delays NOD2 expression and affects NOD2/RIPK2 interactions in intestinal epithelial cells
Q36021426Clinical implications of inflammatory bowel disease genetics on phenotype
Q38596171Clinical profiles of moderate and severe Crohn's disease patients and use of anti-tumor necrosis factor agents: Greek expert consensus guidelines
Q42620808Clustering in time of familial IBD separates ulcerative colitis from Crohn's disease
Q35810933Comparison between Capsule Endoscopy and Magnetic Resonance Enterography for the Detection of Polyps of the Small Intestine in Patients with Familial Adenomatous Polyposis
Q43203641Crohn's disease as an immunodeficiency
Q22252579Crohn's disease: an immune deficiency state
Q22242645Defects in mucosal immunity leading to Crohn's disease
Q35187940Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis
Q36804319Effect of smoking on inflammatory bowel disease: Is it disease or organ specific?
Q26999295Epidemiology of intrafamilial inflammatory bowel disease throughout Europe
Q36397893European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis
Q35068954Familial aggregation in inflammatory bowel disease: is it genes or environment?
Q44448726Familial clustering of Crohn's disease in Israel: prevalence and association with disease severity
Q33996815Family and twin studies in inflammatory bowel disease
Q54492919Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes.
Q47427265Genetic polymorphisms associated with smoking behaviour predict the risk of surgery in patients with Crohn's disease.
Q35997110Inflammatory bowel disease and smoking: a review of epidemiology, pathophysiology, and therapeutic implications
Q37058856Inflammatory bowel disease: genetic and epidemiologic considerations
Q33482165Influence of smoking on colonic gene expression profile in Crohn's disease
Q46767502Is smoking a risk factor for collagenous colitis?
Q37333592LKB1; linking cell structure and tumor suppression
Q35747994Multicenter experience with upper gastrointestinal polyps in pediatric patients with familial adenomatous polyposis
Q37630733Natural history and complications of IBD.
Q39338382Outcome of inflammatory bowel disease patients treated with TNF-α inhibitors: two-year follow-up
Q97692944Polymorphism at rs9264942 is associated with HLA-C expression and inflammatory bowel disease in the Japanese
Q33788228Polymorphisms in interleukin-10 gene according to mutations of NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn's disease.
Q27693862Pulmonary-intestinal cross-talk in mucosal inflammatory disease
Q34013076Resistance to activated protein C is a risk factor for fibrostenosis in Crohn's disease
Q34306458Review article: Ulcerative colitis, smoking and nicotine therapy.
Q33986263Review article: smoking cessation as primary therapy to modify the course of Crohn's disease
Q39963574Risk factors for ulcerative colitis: A population-based, case-control study in Spain
Q45191616Smoking and Crohn's disease: active modification of an independent risk factor (education alone is not enough).
Q57307940Smoking and inflammatory bowel disease
Q44727250Smoking and inflammatory bowel diseases: what in smoking alters the course?
Q28293235Smoking delays the response to treatment in episcleritis and scleritis
Q34410437Smoking in inflammatory bowel disease: impact on disease course and insights into the aetiology of its effect
Q35596242Systemic antibodies towards mucosal bacteria in ulcerative colitis and Crohn's disease differentially activate the innate immune response
Q57265443The IBD International Genetics Consortium Provides Further Evidence for Linkage to IBD4 and Shows Gene-Environment Interaction
Q35793841The Influence of Second-Hand Cigarette Smoke Exposure during Childhood and Active Cigarette Smoking on Crohn's Disease Phenotype Defined by the Montreal Classification Scheme in a Western Cape Population, South Africa
Q42689162The history of genetics in inflammatory bowel disease
Q57266703The impact of new screening protocol on individuals at increased risk of colorectal cancer
Q38609224The impact of smoking in Crohn's disease: no smoke without fire
Q33561021The recurrence risk of genetic complex diseases
Q54483231The utility of capsule endoscopy small bowel surveillance in patients with polyposis.
Q22252338Tobacco and IBD: relevance in the understanding of disease mechanisms and clinical practice
Q37066146Tobacco use increases susceptibility to bacterial infection
Q21198788Ulcerative colitis and Crohn's disease: is Mycobacterium avium subspecies paratuberculosis the common villain?
Q35065326Ulcerative colitis in smokers, non-smokers and ex-smokers
Q36304034Update on the etiology, pathogenesis and diagnosis of ulcerative colitis
Q41271514Vitamin D Deficiency Increases the Risk for Moderate to Severe Disease Activity in Crohn's Disease Patients in South Africa, Measured by the Harvey Bradshaw Index

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