Core-glycosylated mucin-like repeats from MUC1 are an apical targeting signal

scientific article published on 20 September 2011

Core-glycosylated mucin-like repeats from MUC1 are an apical targeting signal is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M111.289504
P932PMC publication ID3234732
P698PubMed publication ID21937430

P2093author name stringSandra J Gendler
Carol L Kinlough
Rebecca P Hughey
Ora A Weisz
Paul A Poland
Di Mo
Polly E Mattila
P2860cites workContributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopyQ40098307
Apical sorting by galectin-3-dependent glycoprotein clusteringQ40167356
Delivery of raft-associated, GPI-anchored proteins to the apical surface of polarized MDCK cells by a transcytotic pathwayQ40572614
Structural determinants required for apical sorting of an intestinal brush-border membrane proteinQ40897786
The epithelial mucin MUC1 contains at least two discrete signals specifying membrane localization in cellsQ41237208
The role of carbohydrates in vectorial exocytosis. The secretion of the gp 80 glycoprotein complex in a ricin-resistant mutant of MDCK cellsQ41699044
1-benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside blocks the apical biosynthetic pathway in polarized HT-29 cells.Q44509770
MUC1 membrane trafficking is modulated by multiple interactionsQ45096221
Recycling of MUC1 is dependent on its palmitoylation.Q50737955
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.Q51767552
Requirement for Galectin-3 in Apical Protein SortingQ57360370
Prognostic significance of MUC1 epithelial mucin expression in breast cancerQ72131263
Differential glycosylation of MUC1 in tumors and transfected epithelial and lymphoblastoid cell linesQ73168413
Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell lineQ73865012
High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cellsQ77895388
Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3Q24311744
Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation stateQ24548387
Mucins in cancer: function, prognosis and therapyQ24633765
Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary glandQ28208406
Structure and function of the cell surface (tethered) mucinsQ28248285
Apical membrane proteins are transported in distinct vesicular carriersQ31010945
Identification of common and unique peptide substrate preferences for the UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases T1 and T2 derived from oriented random peptide substratesQ33254101
Isoform-specific O-glycosylation of osteopontin and bone sialoprotein by polypeptide N-acetylgalactosaminyltransferase-1.Q33569664
Glycans in post-Golgi apical targeting: sorting signals or structural props?Q33688015
Pathways of O-glycan biosynthesis in cancer cellsQ33783697
MUC1: the polymorphic appearance of a human mucinQ33891616
All in the family: the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferasesQ34183333
The importance of MUC1 cellular localization in patients with breast carcinoma: an immunohistologic study of 71 patients and review of the literatureQ34273106
Nucleofection disrupts tight junction fence function to alter membrane polarity of renal epithelial cellsQ34305517
Core2 O-glycan structure is essential for the cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV during intestinal cell differentiationQ34333766
Localization of O-glycosylation sites on glycopeptide fragments from lactation-associated MUC1. All putative sites within the tandem repeat are glycosylation targets in vivoQ34440632
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.Q34471553
Identification and characterization of endogenous galectins expressed in Madin Darby canine kidney cells.Q34675709
Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteinsQ35950439
GalNAc-alpha-O-benzyl inhibits NeuAcalpha2-3 glycosylation and blocks the intracellular transport of apical glycoproteins and mucus in differentiated HT-29 cells.Q36255476
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cellsQ36274330
Role of N- and O-glycans in polarized biosynthetic sortingQ36336692
MUC1 traverses apical recycling endosomes along the biosynthetic pathway in polarized MDCK cellsQ36761932
Specific N-glycans direct apical delivery of transmembrane, but not soluble or glycosylphosphatidylinositol-anchored forms of endolyn in Madin-Darby canine kidney cellsQ36781688
Taking the scenic route: biosynthetic traffic to the plasma membrane in polarized epithelial cellsQ37488634
The role of galectins in protein traffickingQ37570622
Apical trafficking in epithelial cells: signals, clusters and motorsQ37634760
Differential sorting and Golgi export requirements for raft-associated and raft-independent apical proteins along the biosynthetic pathwayQ39599824
Apical cargo traverses endosomal compartments on the passage to the cell surfaceQ39940992
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectglycosylationQ898365
P304page(s)39072-39081
P577publication date2011-09-20
P1433published inJournal of Biological ChemistryQ867727
P1476titleCore-glycosylated mucin-like repeats from MUC1 are an apical targeting signal
P478volume286