scholarly article | Q13442814 |
P50 | author | Jerry Adams | Q6183179 |
Andreas Strasser | Q38803763 | ||
P2093 | author name string | Priscilla N Kelly | |
Alex R D Delbridge | |||
Stephanie Grabow | |||
P2860 | cites work | The Hallmarks of Cancer | Q221226 |
Bim is a suppressor of Myc-induced mouse B cell leukemia | Q37647369 | ||
Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases | Q37921609 | ||
Treatment with a BH3 mimetic overcomes the resistance of latency III EBV (+) cells to p53-mediated apoptosis | Q38798819 | ||
A BACH2-BCL2L1 fusion gene resulting from a t(6;20)(q15;q11.2) chromosomal translocation in the lymphoma cell line BLUE-1. | Q39574938 | ||
Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM. | Q40479135 | ||
Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. | Q41714456 | ||
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis | Q41860419 | ||
Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc. | Q47579113 | ||
MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes | Q53398443 | ||
E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells. | Q53483651 | ||
The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice | Q57338720 | ||
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice | Q57338722 | ||
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18) | Q59085244 | ||
Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice | Q72600081 | ||
Antiapoptotic BCL-2 is required for maintenance of a model leukemia | Q80591496 | ||
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
Suppression of tumorigenesis by the p53 target PUMA | Q24563144 | ||
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa | Q28204059 | ||
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways | Q28213279 | ||
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells | Q28294137 | ||
Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes | Q28510299 | ||
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues | Q28512628 | ||
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair | Q28586758 | ||
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice | Q28593186 | ||
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement | Q28594711 | ||
The BCL-2 protein family: opposing activities that mediate cell death | Q29547380 | ||
An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 | ||
The landscape of somatic copy-number alteration across human cancers | Q29547648 | ||
Induction of apoptosis in fibroblasts by c-myc protein | Q29614346 | ||
The Bcl2 family: regulators of the cellular life-or-death switch | Q29614982 | ||
ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor | Q29616727 | ||
Mechanisms promoting translocations in editing and switching peripheral B cells | Q34008189 | ||
BH3-Only proteins-essential initiators of apoptotic cell death | Q34117362 | ||
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation | Q34245495 | ||
Apoptotic cell death induced by c-myc is inhibited by bcl-2. | Q34255589 | ||
Cooperative interaction between c-myc and bcl-2 proto-oncogenes | Q34255596 | ||
Mcl-1 is essential for germinal center formation and B cell memory | Q34348204 | ||
Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance | Q34369809 | ||
Endogenous bcl-2 is not required for the development of Emu-myc-induced B-cell lymphoma | Q35828796 | ||
Progenitor tumours from Emu-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cell survival | Q35904282 | ||
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants | Q36142180 | ||
The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells | Q36354457 | ||
bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. | Q36366215 | ||
Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis | Q36846076 | ||
Diagnosing and exploiting cancer's addiction to blocks in apoptosis | Q37059647 | ||
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? | Q37100016 | ||
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins | Q37309119 | ||
The ups and downs of Myc biology | Q37644952 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 6380-6386 | |
P577 | publication date | 2011-10-12 | |
P1433 | published in | Blood | Q885070 |
P1476 | title | Endogenous Bcl-xL is essential for Myc-driven lymphomagenesis in mice | |
P478 | volume | 118 |
Q34259242 | A two-way street: reciprocal regulation of metabolism and signalling. |
Q50018704 | Anti-apoptotic A1 is not essential for lymphoma development in Eµ-Myc mice but helps sustain transplanted Eµ-Myc tumour cells |
Q42177793 | BCL-W has a fundamental role in B cell survival and lymphomagenesis |
Q36675203 | Bcl-2 is a critical mediator of intestinal transformation |
Q38735628 | Bcl-2 proteins in development, health, and disease of the hematopoietic system. |
Q36162671 | Context-specific roles for paracrine IL-6 in lymphomagenesis |
Q36774970 | Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis. |
Q38115674 | Decoding and unlocking the BCL-2 dependency of cancer cells |
Q59606812 | Functional antagonism between pro-apoptotic BIM and anti-apoptotic BCL-XL in MYC-induced lymphomagenesis |
Q56335042 | Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer |
Q64054212 | IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis |
Q57068289 | Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression |
Q36349985 | Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199) |
Q38742807 | MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis. |
Q57036262 | MYC-driven malignant transformation of mature murine B cells requires inhibition of both intrinsic apoptosis and p53 activity |
Q37542446 | Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis |
Q36473581 | Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice |
Q40812418 | Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance |
Q36762189 | Targeting MYC in cancer therapy: RNA processing offers new opportunities |
Q90047057 | Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer |
Q37488736 | Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53 |
Q60916539 | Targeting the Bcl-2 Family in B Cell Lymphoma |
Q38193997 | Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies? |
Q36067778 | The BCL-2 protein family, BH3-mimetics and cancer therapy |
Q51213072 | The BET Bromodomain Inhibitor JQ1 Suppresses Chondrosarcoma Cell Growth via Regulation of YAP/p21/c-Myc Signaling. |
Q36979947 | Toll-like receptor agonists induce apoptosis in mouse B-cell lymphoma cells by altering NF-κB activation |
Q91139907 | Transformation of mature mouse B cells into malignant plasma cells in vitro via introduction of defined genetic elements |
Q42388879 | Turning off the BCL-2 switch to prevent intestinal tumorigenesis |
Q37594415 | Using body temperature, food and water consumption as biomarkers of disease progression in mice with Eμ-myc lymphoma |
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