Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice

scientific article published on August 1999

Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1999PNAS...9610152S
P356DOI10.1073/PNAS.96.18.10152
P932PMC publication ID17858
P698PubMed publication ID10468578
P5875ResearchGate publication ID238576745

P50authorStephen A. DuncanQ30512288
Maria Angeles NavasQ42866220
P2093author name stringM Stoffel
D Q Shih
S Kuwajima
P2860cites workTargeted disruption of the gene encoding hepatocyte nuclear factor 3gamma results in reduced transcription of hepatocyte-specific genesQ24522569
Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivoQ28507284
Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndromeQ28512217
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionallyQ28575328
Leptin and the regulation of body weight in mammalsQ29615976
HNF-3 beta is essential for node and notochord formation in mouse developmentQ29616180
The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryoQ29618427
Interactions between the neuropeptide Y system and the hypothalamic-pituitary-adrenal axisQ33539558
Nucleosome positioning by the winged helix transcription factor HNF3Q35187279
Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic functionQ36653134
Glucagon gene expression is negatively regulated by hepatocyte nuclear factor 3 betaQ36653479
Modulation of liver-specific transcription by interactions between hepatocyte nuclear factor 3 and nuclear factor 1 binding DNA in close appositionQ36678807
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genesQ36763447
Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteinsQ36849257
Physiology and pathophysiology of glucagonQ37194582
Structure and pancreatic expression of the insulin and glucagon genesQ37439635
Immediate and time-dependent effects of glucose on insulin release from rat pancreatic tissue. Evidence for different mechanisms of actionQ40152489
Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreasQ40920945
Transcriptional control of genes that regulate glycolysis and gluconeogenesis in adult liverQ41773037
Persistent neonatal hypoglycaemia due to glucagon deficiencyQ42280148
Neuroendocrine interactions between galanin, opioids, and neuropeptide Y in the control of reproduction and appetiteQ43070493
Regulation of a transcription factor network required for differentiation and metabolismQ47762177
Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork headQ48232472
An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array.Q52545485
Glucagon deficiency causing severe neonatal hypoglycemia in a patient with normal insulin secretionQ67678784
Disorders of carbohydrate metabolism in infancyQ67838345
Mesodermal patterning by an inducer gradient depends on secondary cell-cell communicationQ72787931
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)10152-10157
P577publication date1999-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleImpaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice
P478volume96

Reverse relations

cites work (P2860)
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Q40760347Adenovirus-mediated increase of HNF-3 levels stimulates expression of transthyretin and sonic hedgehog, which is associated with F9 cell differentiation toward the visceral endoderm lineage
Q24800214An efficient method to successively introduce transgenes into a given genomic locus in the mouse
Q28657819Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study
Q28589587Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis
Q38538387Current perspectives on FOXA1 regulation of androgen receptor signaling and prostate cancer
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Q37612773Differentiated human stem cells resemble fetal, not adult, β cells
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Q36102674Embryonic development of the liver
Q33830160Expression profile analysis of the inflammatory response regulated by hepatocyte nuclear factor 4α
Q24607057FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis
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Q35532767FOXA1: master of steroid receptor function in cancer
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Q58776729Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation
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