Transcription factors in mouse lung development and function

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Transcription factors in mouse lung development and function is …
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review articleQ7318358
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P356DOI10.1152/AJPLUNG.2001.280.5.L823
P698PubMed publication ID11290504

P2093author name stringCosta RH
Kalinichenko VV
Lim L
P2860cites workSequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plateQ48090165
HNF-3/forkhead homologue-4 influences lung morphogenesis and respiratory epithelial cell differentiation in vivoQ48117336
HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lungQ48208908
Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork headQ48232472
Conditional expression of fibroblast growth factor-7 in the developing and mature lung.Q52169169
Hoxb-5 expression in the developing mouse lung suggests a role in branching morphogenesis and epithelial cell fate.Q52191086
Expression of Hoxb genes in the developing mouse foregut and lung.Q52200562
Vascularization of the mouse embryo: A study of flk‐1, tek, tie, and vascular endothelial growth factor expression during developmentQ52208633
PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and AlveogenesisQ57415025
FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfacesQ22003943
Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3betaQ22253477
The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIBQ24309276
Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2Q24310457
Upstream enhancer activity in the human surfactant protein B gene is mediated by thyroid transcription factor 1Q24310665
The winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryoQ24311998
The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivativesQ24314519
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formationQ24316945
Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissuesQ24319881
Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domainQ24320307
The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterizationQ24322793
Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factorsQ24594377
Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heartQ24606117
Analysis of hepatocyte nuclear factor-3 beta protein domains required for transcriptional activation and nuclear targetingQ24629290
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5Q27731950
Structural changes in the region directly adjacent to the DNA-binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteinsQ27756859
Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation developmentQ28251735
The fork head domain: a novel DNA binding motif of eukaryotic transcription factors?Q28257620
The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitaryQ28272956
Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagusQ28281760
Fgf10 is essential for limb and lung formationQ28295033
Interaction of a liver-specific nuclear factor with the fibrinogen and alpha 1-antitrypsin promotersQ28299313
Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryosQ28505450
GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic developmentQ28505891
Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetryQ28506579
The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiationQ28506633
Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lungQ28506850
Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivoQ28507284
Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1Q28509114
Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain familyQ28509713
Evidence for the involvement of the Gli gene family in embryonic mouse lung developmentQ28510253
Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null miceQ28511679
Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryosQ28511927
Mouse forkhead (winged helix) gene LUN encodes a transactivator that acts in the lungQ28513929
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionallyQ28575328
Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epitheliumQ28577694
Different roles for PDGF-alpha and -beta receptors in embryonic lung developmentQ28582851
Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidneyQ28585814
GATA4 transcription factor is required for ventral morphogenesis and heart tube formationQ28586495
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endotheliumQ28587604
Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defectsQ28591369
Sonic hedgehog is essential to foregut developmentQ28591429
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesisQ28592331
Loss of Hoxa5 gene function in mice perturbs intestinal maturationQ28593222
Failure of blood-island formation and vasculogenesis in Flk-1-deficient miceQ28593600
GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesodermQ28594534
Mechanisms of angiogenesisQ29547485
Identification of hepatocyte nuclear factor-3 binding sites in the Clara cell secretory protein geneQ38315643
Expression of hepatocyte nuclear factor-3alpha in rat prostate, seminal vesicle, and bladderQ38339613
Interferon-gamma regulation of Clara cell gene expression: in vivo and in vitroQ38345330
Hepatocyte nuclear factor 3beta participates in the transcriptional regulation of the thyroperoxidase promoterQ38360662
The winged-helix transcription factor Trident is expressed in cycling cellsQ39719914
Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cellsQ40019295
The specificity of homeotic gene functionQ40375266
Epithelial-mesenchymal interactions in lung developmentQ40623623
TGT3, thyroid transcription factor I, and Sp1 elements regulate transcriptional activity of the 1.3-kilobase pair promoter of T1alpha, a lung alveolar type I cell geneQ41087119
Control of apolipoprotein AI gene expression through synergistic interactions between hepatocyte nuclear factors 3 and 4.Q41192616
The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 familiesQ41545138
Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor TridentQ46489690
Expression of the platelet-derived growth factor beta receptor during organogenesis and tissue differentiation in the mouse embryoQ46670200
Temporal-spatial distribution of hepatocyte nuclear factor-3beta in developing human lung and other foregut derivativesQ47813869
The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreasQ48040924
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF geneQ29547732
Abnormal blood vessel development and lethality in embryos lacking a single VEGF alleleQ29547733
Vascular-specific growth factors and blood vessel formationQ29614780
HNF-3 beta is essential for node and notochord formation in mouse developmentQ29616180
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1Q29617416
The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryoQ29618427
Regulation of Clara cell secretory protein gene transcription by thyroid transcription factor-1.Q30040822
Differential expression of forkhead box transcription factors following butylated hydroxytoluene lung injuryQ32128097
A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genesQ33577523
Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteinsQ33597105
Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promotersQ33660554
Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lungQ33682260
Forkhead transcription factor HFH-4 and respiratory epithelial cell differentiationQ33697860
The homeodomain-containing proteins: an update on their interacting partnersQ33790697
Positive and negative regulatory elements in the mouse albumin enhancerQ33840270
The molecular basis of lung morphogenesisQ33855377
Forkhead transcription factor HFH-4 expression is temporally related to ciliogenesisQ33869260
Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phaseQ33960953
Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyteQ33964626
Abnormalities of the genitourinary tract in female mice lacking GATA5.Q33964653
The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.Q34066369
Five years on the wings of fork headQ34398426
Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient miceQ35617423
Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer regionQ35774807
Targeted null-mutation in the vascular endothelial-cadherin gene impairs the organization of vascular-like structures in embryoid bodiesQ36182679
Six members of the mouse forkhead gene family are developmentally regulatedQ36481228
The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expressionQ36563623
The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helixQ36651086
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axisQ36664519
Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head proteinQ36698768
The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphologyQ36730949
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genesQ36763447
The restricted promoter activity of the liver transcription factor hepatocyte nuclear factor 3 beta involves a cell-specific factor and positive autoactivationQ36812290
Role of hepatocyte nuclear factor-3 alpha and hepatocyte nuclear factor-3 beta in Clara cell secretory protein gene expression in the bronchiolar epitheliumQ38295318
The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distributionQ38309705
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)L823-38
P577publication date2001-05-01
P1433published inAmerican Journal of Physiology - Lung Cellular and Molecular PhysiologyQ4352992
P1476titleTranscription factors in mouse lung development and function
P478volume280