| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0079-6123(03)46029-9 |
| P698 | PubMed publication ID | 14699980 |
| P50 | author | Marc J. Ruitenberg | Q43677448 |
| P2093 | author name string | Bas Blits | |
| Joost Verhaagen | |||
| Gerard J Boer | |||
| William T Hendriks | |||
| P2860 | cites work | Tight control of gene expression in mammalian cells by tetracycline-responsive promoters | Q24564850 |
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| Lumbar transplant of neurons genetically modified to secrete brain-derived neurotrophic factor attenuates allodynia and hyperalgesia after sciatic nerve constriction | Q28571071 | ||
| TrkC overexpression enhances survival and migration of neural stem cell transplants in the rat spinal cord | Q28572313 | ||
| In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector | Q29547503 | ||
| HIV-1 integration in the human genome favors active genes and local hotspots | Q29618457 | ||
| Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells | Q30476168 | ||
| Lentiviral vectors: turning a deadly foe into a therapeutic agent | Q33840989 | ||
| Olfactory ensheathing cells and Schwann cells differ in their in vitro interactions with astrocytes | Q33927056 | ||
| Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury | Q34017309 | ||
| Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression | Q34060793 | ||
| Adeno-associated virus vectors for gene therapy: more pros than cons? | Q34080580 | ||
| Delivery of therapeutic molecules into the CNS. | Q34098346 | ||
| Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches | Q34156542 | ||
| Plasticity of motor systems after incomplete spinal cord injury | Q34205594 | ||
| Neurotrophic factors and gene therapy in spinal cord injury | Q34279632 | ||
| Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function | Q34384227 | ||
| Spinal-cord injury | Q34530651 | ||
| Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair | Q34657645 | ||
| Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord | Q46317687 | ||
| Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease | Q47695139 | ||
| Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. | Q47892533 | ||
| Adenoviral vector-mediated gene delivery to injured rat peripheral nerve | Q47980949 | ||
| Regeneration into the spinal cord of transected dorsal root axons is promoted by ensheathing glia transplants | Q48112615 | ||
| Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion | Q48190429 | ||
| Neurotrophins promote regeneration of sensory axons in the adult rat spinal cord | Q48259746 | ||
| Spinal cord injury: bridging the lesion and the role of neurotrophic factors in repair. | Q48291049 | ||
| Regeneration and sprouting of chronically injured corticospinal tract fibers in adult rats promoted by NT-3 and the mAb IN-1, which neutralizes myelin-associated neurite growth inhibitors | Q48313548 | ||
| Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury. | Q48316061 | ||
| Expression of members of the trk family in the developing postnatal rat brain | Q48319176 | ||
| A model system for in vivo gene transfer into the central nervous system using an adenoviral vector | Q48325479 | ||
| Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells. | Q48329610 | ||
| Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hind-limb function | Q48344978 | ||
| Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat. | Q48401519 | ||
| Grafts of BDNF-producing fibroblasts rescue axotomized rubrospinal neurons and prevent their atrophy | Q48418361 | ||
| Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat. | Q48558584 | ||
| BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration | Q48567818 | ||
| Mouse astrocytes store and deliver brain-derived neurotrophic factor using the non-catalytic gp95trkB receptor | Q48578116 | ||
| Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells | Q48626271 | ||
| Adenoviral vector-directed expression of neurotrophin-3 in rat dorsal root ganglion explants results in a robust neurite outgrowth response | Q48653102 | ||
| Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo | Q48654513 | ||
| Adenoviral vector-mediated gene expression in the nervous system of immunocompetent Wistar and T cell-deficient nude rats: preferential survival of transduced astroglial cells in nude rats | Q48684249 | ||
| BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth | Q48736215 | ||
| Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons | Q48821253 | ||
| Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons | Q48850117 | ||
| Astrocytes infected with replication-defective adenovirus containing a secreted form of CNTF or NT3 show enhanced support of neuronal populations in vitro | Q48983208 | ||
| Regulation of Trk receptors following contusion of the rat spinal cord | Q49067304 | ||
| Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats | Q49156758 | ||
| Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord. | Q44184245 | ||
| Hyperplastic changes within the leptomeninges of the rat and monkey in response to chronic intracerebroventricular infusion of nerve growth factor | Q44338024 | ||
| Potential use of embryonic stem cells for the treatment of mouse parkinsonian models: improved behavior by transplantation of in vitro differentiated dopaminergic neurons from embryonic stem cells | Q44360312 | ||
| Expression of human HPRT mRNA in brains of mice infected with a recombinant herpes simplex virus-1 vector | Q44471123 | ||
| Immunological instability of persistent adenovirus vectors in the brain: peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination | Q44907561 | ||
| Immune responses to adenoviral vectors during gene transfer in the brain | Q45269702 | ||
| Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion | Q45738162 | ||
| Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters | Q45764253 | ||
| Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector | Q45769447 | ||
| Beta-galactosidase as a marker in the peripheral and neural tissues of the herpes simplex virus-infected mouse | Q45840767 | ||
| Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV) vector-mediated over-expression of BDNF in the rat spinal cord | Q45855288 | ||
| Gene therapy. Seeking the cause of induced leukemias in X-SCID trial | Q45858033 | ||
| An adenovirus vector for gene transfer into neurons and glia in the brain | Q45874317 | ||
| The use of a recombinant lentiviral vector for ex vivo gene transfer into the rat CNS. | Q45874689 | ||
| Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors | Q45875094 | ||
| Targeting and gene expression in spinal cord motor neurons following intramuscular inoculation of an HSV-1 vector. | Q45882672 | ||
| Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord. | Q45883608 | ||
| Intraspinal grafting of fibroblasts genetically modified by recombinant adenoviruses | Q45887325 | ||
| Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells | Q46076888 | ||
| Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury | Q46096843 | ||
| Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. | Q46187210 | ||
| A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. | Q50759596 | ||
| Neurotrophin-3 expressed in situ induces axonal plasticity in the adult injured spinal cord. | Q52549450 | ||
| Emerging roles for semaphorins in neural regeneration | Q56592755 | ||
| Functional Recovery of Paraplegic Rats and Motor Axon Regeneration in Their Spinal Cords by Olfactory Ensheathing Glia | Q58028333 | ||
| Intracerebroventricular infusion of nerve growth factor induces pain-like response in rats | Q59674065 | ||
| Transfer of a foreign gene into the brain using adenovirus vectors | Q64377820 | ||
| Adenoviral gene transfer to the injured spinal cord of the adult rat | Q64380441 | ||
| Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function | Q64380660 | ||
| Adenovirus gene transfer causes inflammation in the brain | Q64383186 | ||
| Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord | Q71215316 | ||
| Clinical syndromes associated with disproportionate weakness of the upper versus the lower extremities after cervical spinal cord injury | Q71367723 | ||
| BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo | Q71383325 | ||
| Peripheral nerve regeneration | Q71584818 | ||
| A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration | Q71647850 | ||
| Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan | Q72896530 | ||
| Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and neurofilament-M | Q73107528 | ||
| Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord | Q73226161 | ||
| Survival effects of BDNF and NT-3 on axotomized rubrospinal neurons depend on the temporal pattern of neurotrophin administration | Q73537451 | ||
| Acute inflammatory response in spinal cord following impact injury | Q74531532 | ||
| HveC (nectin-1) is expressed at high levels in sensory neurons, but not in motor neurons, of the rat peripheral nervous system | Q74583781 | ||
| Apoptosis in cellular compartments of rat spinal cord after severe contusion injury | Q74800587 | ||
| Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery | Q77319899 | ||
| New method for transplantation of neurosphere cells into injured spinal cord through cerebrospinal fluid in rat | Q77503875 | ||
| Transplantation of genetically modified fibroblasts expressing BDNF in adult rats with a subtotal hemisection improves specific motor and sensory functions | Q77546518 | ||
| Apoptosis of spinal interneurons induced by sciatic nerve axotomy in the neonatal rat is counteracted by nerve growth factor and ciliary neurotrophic factor | Q78051954 | ||
| Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus | Q78128999 | ||
| Outcry greets US plan to test smallpox vaccine on children | Q78515999 | ||
| Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury | Q34745372 | ||
| Neural cells derived from adult bone marrow and umbilical cord blood. | Q34805868 | ||
| Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation | Q35761500 | ||
| Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte grafts | Q36012180 | ||
| Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection | Q36720691 | ||
| Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia | Q36851040 | ||
| Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. | Q36896476 | ||
| Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord | Q36898625 | ||
| Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector | Q37251114 | ||
| An adenovirus type 5 early gene function regulates expression of other early viral genes | Q37338696 | ||
| An inquiry into the mechanisms of herpes simplex virus latency | Q39159400 | ||
| Effects on movement of surgical incisions into the human spinal cord | Q39485727 | ||
| Grafting genetically modified cells to the brain: possibilities for the future | Q39694407 | ||
| Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins | Q40583034 | ||
| Injury-induced class 3 semaphorin expression in the rat spinal cord | Q40640541 | ||
| Chronic intrathecal infusions after spinal cord injury cause scarring and compression | Q40690508 | ||
| Gene delivery to neurons: is herpes simplex virus the right tool for the job? | Q40729078 | ||
| Bcl-2 and GDNF delivered by HSV-mediated gene transfer after spinal root avulsion provide a synergistic effect | Q40749988 | ||
| Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo | Q40814855 | ||
| Neurotrophic and migratory properties of an olfactory ensheathing cell line | Q40821731 | ||
| Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease | Q40846012 | ||
| Viral vectors, tools for gene transfer in the nervous system | Q40852313 | ||
| Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus. | Q40866683 | ||
| Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons | Q40890513 | ||
| Functional regeneration of sensory axons into the adult spinal cord. | Q40902160 | ||
| Stable gene transfer to the nervous system using a non-primate lentiviral vector | Q40910553 | ||
| The use of nonneuronal cells for gene delivery | Q40911146 | ||
| NT-3 promotes growth of lesioned adult rat sensory axons ascending in the dorsal columns of the spinal cord. | Q40914375 | ||
| Immune responses to adenovirus vectors in the nervous system | Q40922367 | ||
| Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons. | Q40926394 | ||
| Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. | Q40952232 | ||
| Degeneration and regeneration of axons in the lesioned spinal cord | Q40980911 | ||
| Neuroprotection of spinal motoneurons following targeted transduction with an adenoviral vector carrying the gene for glial cell line-derived neurotrophic factor | Q41007774 | ||
| Stem cells in the central nervous system | Q41116811 | ||
| Physiology of the neurotrophins | Q41132669 | ||
| The neurotrophins and CNTF: two families of collaborative neurotrophic factors | Q41132721 | ||
| Regulation of spinal motoneuron survival by GDNF during development and following injury | Q41150099 | ||
| Gene therapy for central nervous system injury: the use of cationic liposomes: an invited review | Q41512299 | ||
| Potential use of herpes simplex virus (HSV) vectors for gene therapy of neurological disorders | Q41543685 | ||
| Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system | Q41606073 | ||
| Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1. | Q41691715 | ||
| Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain | Q42280576 | ||
| Regeneration of adult rat CNS axons into peripheral nerve autografts: ultrastructural studies of the early stages of axonal sprouting and regenerative axonal growth | Q42449615 | ||
| Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats | Q42451396 | ||
| Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain | Q42471241 | ||
| Differential distribution of exogenous BDNF, NGF, and NT‐3 in the brain corresponds to the relative abundance and distribution of high‐affinity and low‐affinity neurotrophin receptors | Q42482319 | ||
| Modulation of neuronal survival and axonal growth in vivo by tetracycline-regulated neurotrophin expression. | Q42506402 | ||
| Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor | Q42528873 | ||
| Extensive sprouting of sensory afferents and hyperalgesia induced by conditional expression of nerve growth factor in the adult spinal cord. | Q42800909 | ||
| In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum | Q42831252 | ||
| Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy. | Q43585496 | ||
| Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery | Q43685007 | ||
| Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins. | Q43805370 | ||
| Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression | Q43839045 | ||
| Mechanism of activation of early viral transcription by the adenovirus E1A gene product | Q43950071 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 451-476 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | Progress in Brain Research | Q15800382 |
| P1476 | title | Viral vector-mediated gene transfer of neurotrophins to promote regeneration of the injured spinal cord | |
| P478 | volume | 146 |
| Q38220813 | A sight on the current nanoparticle-based gene delivery vectors |
| Q36528587 | Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? |
| Q36883772 | Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease. |
| Q35112769 | Chondroitinase activity can be transduced by a lentiviral vector in vitro and in vivo. |
| Q36415316 | Clinical canine spinal cord injury provides an opportunity to examine the issues in translating laboratory techniques into practical therapy. |
| Q35907307 | Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: superiority to camp-mediated effects. |
| Q36431214 | Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats |
| Q34713207 | Effect of neuroglobin genetically modified bone marrow mesenchymal stem cells transplantation on spinal cord injury in rabbits. |
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| Q36020714 | Setting the stage for functional repair of spinal cord injuries: a cast of thousands |
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| Q42142426 | TGF-β(1) in retinal ganglion cells in rats with chronic ocular hypertension: its expression and anti-apoptotic effect |
| Q37350126 | The application of viral vectors to enhance regeneration after peripheral nerve repair. |
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| Q38416280 | Therapeutical Strategies for Spinal Cord Injury and a Promising Autologous Astrocyte-Based Therapy Using Efficient Reprogramming Techniques |
| Q27025285 | Translational spinal cord injury research: preclinical guidelines and challenges |
| Q48155979 | Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: Survival, migration, axon association, and functional recovery |
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