Immune responses to adenovirus vectors in the nervous system

scientific article published on November 1996

Immune responses to adenovirus vectors in the nervous system is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0166-2236(96)10060-6
P698PubMed publication ID8931276

P2093author name stringWood MJ
Kajiwara K
Wood KJ
Charlton HM
Byrnes AP
P2860cites workAn Essential Role for Type 1 Interferon-γ in Terminating Persistent Viral InfectionQ58828960
Transfer of a foreign gene into the brain using adenovirus vectorsQ64377820
Retrograde transfer of replication deficient recombinant adenovirus vector in the central nervous system for tracing studiesQ64383045
Adenovirus gene transfer causes inflammation in the brainQ64383186
Adenovirus entry into host cells: a role for alpha(v) integrinsQ64383600
T-lymphocyte entry into the central nervous systemQ70156307
Immune reactions following systemic immunization prior or subsequent to intrastriatal transplantation of allogeneic mesencephalic tissue in adult ratsQ72153719
Gene therapy for neurological disordersQ72157283
Demyelination in the central nervous system following a delayed-type hypersensitivity response to bacillus Calmette-GuérinQ72244649
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vectorQ29547503
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachmentQ29615852
Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivoQ34040679
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transferQ34926866
Liver-directed gene therapy: quantitative evaluation of promoter elements by using in vivo retroviral transductionQ35051812
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapyQ35232341
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenovirusesQ35837026
Induction of MHC class I genes in neuronsQ36688665
The immune response to intracerebral neural graftsQ36705265
A mouse model for investigating the molecular pathogenesis of adenovirus pneumoniaQ37412249
Macrophages and inflammation in the central nervous systemQ40489629
Nervous tissue as an immune compartment: the dialect of the immune response in the CNS.Q40668189
The principles of gene therapy for the nervous systemQ41120773
Development of cell lines capable of complementing E1, E4, and protein IX defective adenovirus type 5 mutantsQ41263288
Pulmonary inflammation induced by incomplete or inactivated adenoviral particlesQ41263315
Neuronal cells are deficient in loading peptides onto MHC class I moleculesQ41620648
MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.Q41664847
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis.Q43535009
Expression of Escherichia coli beta-galactosidase and rat HPRT in the CNS of Macaca mulatta following adenoviral mediated gene transferQ44747875
Immunological instability of persistent adenovirus vectors in the brain: peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelinationQ44907561
The production of focal herpes encephalitis in mice by stereotaxic inoculation of virus. Anatomical and behavioral effectsQ45836737
Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administrationQ45866667
An adenovirus vector for gene transfer into neurons and glia in the brainQ45874317
Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectorsQ45875094
Adenoviral vectors as functional retrograde neuronal tracersQ48106092
The fate of allogeneic and xenogeneic neuronal tissue transplanted into the third ventricle of rodentsQ48278859
A model system for in vivo gene transfer into the central nervous system using an adenoviral vectorQ48325479
Specific Patterns of Defective HSV-1 Gene Transfer in the Adult Central Nervous System: Implications for Gene TargetingQ58822234
P433issue11
P921main subjectAdenoviridaeQ193447
P304page(s)497-501
P577publication date1996-11-01
P1433published inTrends in NeurosciencesQ3538443
P1476titleImmune responses to adenovirus vectors in the nervous system
P478volume19

Reverse relations

cites work (P2860)
Q41058416A gamma34.5 mutant of herpes simplex 1 causes severe inflammation in the brain.
Q48486087APOE epsilon3 gene transfer attenuates brain damage after experimental stroke
Q44684310Absence of toxicity of chronic weekly intravenous gene therapy with pegylated immunoliposomes
Q44082453Adenoviral gene transfer of aspartoacylase into the tremor rat, a genetic model of epilepsy, as a trial of gene therapy for inherited epileptic disorder.
Q45887941Adenoviral gene transfer to spinal-cord neurons: intrathecal vs. intraparenchymal administration
Q41068462Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson's disease
Q45861869Adenoviral vectors for in vivo gene delivery to oligodendrocytes: transgene expression and cytopathic consequences
Q45855527Adenovirus infection induces microglial activation: involvement of mitogen-activated protein kinase pathways
Q35575249Alloimmunisation to donor antigens and immune rejection following foetal neural grafts to the brain in patients with Huntington's disease
Q48594392Application of recombinant adenovirus for in vivo gene delivery to spinal cord
Q36842495Blood-brain barrier transport of non-viral gene and RNAi therapeutics
Q31013320Combining cytotoxic and immune-mediated gene therapy to treat brain tumors
Q92539077Cytokines in Pain: Harnessing Endogenous Anti-Inflammatory Signaling for Improved Pain Management
Q64381079Dopa-producing astrocytes generated by adenoviral transduction of human tyrosine hydroxylase gene: in vitro study and transplantation to hemiparkinsonian model rats
Q45736046Effect of immunity on gene delivery into anterior horn motor neurons by live attenuated herpes simplex virus vector
Q47318878Evolutionary basis of a new gene- and immune-therapeutic approach for the treatment of malignant brain tumors: from mice to clinical trials for glioma patients
Q34152190Future directions in alcoholism research. Genomics and gene transfer.
Q33917592Gene delivery with viral vectors for cerebrovascular diseases
Q46173833Gene targeting in vivo with pegylated immunoliposomes
Q34119431Gene transfer for cerebrovascular disease
Q33904294Gene transfer into rat brain using adenoviral vectors.
Q45747744Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors
Q40604183Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS.
Q45884040High-capacity, helper-dependent, "gutless" adenoviral vectors for gene transfer into brain
Q42861412Immune regulation of transgene expression in the brain: B cells regulate an early phase of elimination of transgene expression from adenoviral vectors
Q36274402Immunological thresholds in neurological gene therapy: highly efficient elimination of transduced cells might be related to the specific formation of immunological synapses between T cells and virus-infected brain cells.
Q34500928Immunology of viral-vector-mediated gene transfer into the brain: an evolutionary and developmental perspective
Q33841658In situ use of suicide genes for therapy of brain tumours
Q33216908In vivo transgene expression from an adenoviral vector is altered following a 6-OHDA lesion of the dopamine system.
Q35131222Inflammation and adaptive immune responses to adenoviral vectors injected into the brain: peculiarities, mechanisms, and consequences
Q45861874Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus
Q42536199Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain.
Q31923956Intravitreal adenoviral gene transfer evokes an immune response in the retina that is directed against the heterologous lacZ transgene product but does not limit transgene expression
Q45877189Local adenoviral expression of Fas ligand upregulates pro-inflammatory immune responses in the CNS.
Q45890414Local gene therapy with CTLA4-immunoglobulin fusion protein in experimental allergic encephalomyelitis.
Q35734505Long-term doxycycline-controlled expression of human tyrosine hydroxylase after direct adenovirus-mediated gene transfer to a rat model of Parkinson's disease.
Q35563389Molecular biology and gene therapy in the treatment of chronic pain.
Q40630598Neurotrophic factors expressed in both cortex and spinal cord induce axonal plasticity after spinal cord injury
Q35163431Noninvasive gene targeting to the brain
Q33985663Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders
Q35161530Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch
Q34757639Preferential and bidirectional labeling of the rubrospinal tract with adenovirus-GFP for monitoring normal and injured axons.
Q36014895Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells
Q64381948Promoter-independent regulation of cell-specific dopamine receptor expression
Q40633580Protective effects of intracerebral adenoviral-mediated GDNF gene transfer in a rat model of Parkinson's disease
Q48515148Reduced inflammatory reactions to the inoculation of helper-dependent adenoviral vectors in traumatically injured rat brain
Q34361466Regulatable and cell-type specific transgene expression in glial cells: prospects for gene therapy for neurological disorders
Q39988205Reversal of mdr1b-dependent multidrug resistance in a rat astrocyte model by adenoviral-delivered short hairpin RNA.
Q45360347Sendai virus vector-mediated brain-derived neurotrophic factor expression ameliorates memory deficits and synaptic degeneration in a transgenic mouse model of Alzheimer's disease
Q33713348Striatal readministration of rAAV vectors reveals an immune response against AAV2 capsids that can be circumvented.
Q48348307Suppression of inflammation by dexamethasone prolongs adenoviral vector-mediated transgene expression in the facial nucleus of the rat.
Q44612690Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase
Q35585191The Trojan Horse Liposome Technology for Nonviral Gene Transfer across the Blood-Brain Barrier
Q41102311The coming of age of the GDNF family and its receptors: gene delivery in a rat Parkinson model may have clinical implications
Q37485007The therapeutic potential of interleukin-10 in neuroimmune diseases.
Q35203194Therapeutic gene silencing in the nervous system
Q34105795Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
Q35576698Translational Paradigms in Cerebrovascular Gene Transfer
Q36249210Treatment of Parkinson's disease : what's on the horizon?
Q45862071Variation in the immune response to adenoviral vectors in the brain: influence of mouse strain, environmental conditions and priming
Q35618384Viral vector-mediated gene transfer of neurotrophins to promote regeneration of the injured spinal cord.
Q36960666Viral vectors for in vivo gene transfer in Parkinson's disease: properties and clinical grade production.

Search more.