| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1999PNAS...9612120C |
| P356 | DOI | 10.1073/PNAS.96.21.12120 |
| P932 | PMC publication ID | 18422 |
| P698 | PubMed publication ID | 10518586 |
| P5875 | ResearchGate publication ID | 12781106 |
| P50 | author | Olga Corti | Q50637251 |
| P2093 | author name string | J Mallet | |
| M Hamon | |||
| N Hanoun | |||
| P Colin | |||
| A Sánchez-Capelo | |||
| P2860 | cites work | Tight control of gene expression in mammalian cells by tetracycline-responsive promoters | Q24564850 |
| Tyrosine hydroxylase: human isoforms, structure and regulation in physiology and pathology | Q28290894 | ||
| Transcriptional activation by tetracyclines in mammalian cells | Q28303934 | ||
| "On-off" effects in patients with Parkinson's disease on chronic levodopa therapy | Q28317866 | ||
| Control of memory formation through regulated expression of a CaMKII transgene | Q29619261 | ||
| Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector | Q34385773 | ||
| Adenovirus-mediated regulable target gene expression in vivo | Q34807993 | ||
| Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted | Q39642143 | ||
| In vivo adenovirus-mediated gene transfer for Parkinson's disease | Q40910774 | ||
| Immune responses to adenovirus vectors in the nervous system | Q40922367 | ||
| Persistent transgene expression in the hypothalamus following stereotaxic delivery of a recombinant adenovirus: suppression of the immune response with cyclosporin | Q41155846 | ||
| Intracerebral tetracycline-dependent regulation of gene expression in grafts of neural precursors. | Q41185726 | ||
| Application of ex vivo gene therapy in the treatment of Parkinson's disease | Q41450683 | ||
| Inducible gene expression in mammalian cells and transgenic mice | Q41628997 | ||
| Tetrahydrobiopterin-dependent functional recovery in 6-hydroxydopamine-treated rats by intracerebral grafting of fibroblasts transfected with tyrosine hydroxylase cDNA | Q41649774 | ||
| Biopterin in human brain and urine from controls and parkinsonian patients: Application of a new radioimmunoassay | Q42241168 | ||
| Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain | Q42280576 | ||
| In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase | Q42828882 | ||
| In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum | Q42831252 | ||
| Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase | Q43185222 | ||
| Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system | Q44902306 | ||
| Immune responses to adenoviral vectors during gene transfer in the brain | Q45269702 | ||
| Inducible long-term gene expression in brain with adeno-associated virus gene transfer | Q45751214 | ||
| Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease. | Q45756120 | ||
| Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts | Q45877347 | ||
| Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. | Q45885499 | ||
| Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system | Q45887839 | ||
| Adenovirus in the brain: recent advances of gene therapy for neurodegenerative diseases. | Q45888258 | ||
| Controlling mammalian gene expression with small molecules | Q45888368 | ||
| Inducible control of gene expression: prospects for gene therapy | Q45889162 | ||
| A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors | Q48233698 | ||
| Transgenic animals with inducible, targeted gene expression in brain | Q48398754 | ||
| The immunosuppressant FK506 prolongs transgene expression in brain following adenovirus-mediated gene transfer | Q48659780 | ||
| Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra | Q48713669 | ||
| Retroviral delivery and tetracycline-dependent expression of IL-1beta-converting enzyme (ICE) in a rat glioma model provides controlled induction of apoptotic death in tumor cells. | Q48850704 | ||
| Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system. | Q48876521 | ||
| Neurochemical effects following peripheral administration of tetrahydropterin derivatives to the hph-1 mouse. | Q49087031 | ||
| Tetrahydrobiopterin in Striatum: Localization in Dopamine Nerve Terminals and Role in Catecholamine Synthesis | Q49156811 | ||
| Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease | Q64383353 | ||
| Tyrosine hydroxylase cofactor (tetrahydrobiopterin) in parkinsonism | Q64763391 | ||
| Biochemical and electrophysiological evidence for an agonist action of CM 57493 at pre- and postsynaptic 5-hydroxytryptamine1A receptors in brain | Q69297345 | ||
| Behavioral effects and gene delivery in a rat model of Parkinson's disease | Q71967787 | ||
| Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats | Q72707580 | ||
| Estimation of nuclear population from microtome sections | Q82126847 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Parkinson's disease | Q11085 |
| doxycycline | Q422442 | ||
| Adenoviridae | Q193447 | ||
| P1104 | number of pages | 6 | |
| P304 | page(s) | 12120-12125 | |
| P577 | publication date | 1999-10-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Long-term doxycycline-controlled expression of human tyrosine hydroxylase after direct adenovirus-mediated gene transfer to a rat model of Parkinson's disease | |
| P478 | volume | 96 |
| Q38075068 | A next step in adeno-associated virus-mediated gene therapy for neurological diseases: regulation and targeting. |
| Q44547034 | Behavioral correction of Parkinsonian rats following the transplantation of immortalized fibroblasts genetically modified with TH and GCH genes |
| Q47248889 | Brain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral, biochemical, neurochemical and histological alterations in mice |
| Q34193457 | Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain |
| Q36969314 | Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behaviora |
| Q36989384 | Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease |
| Q35582092 | Controlled Striatal DOPA Production From a Gene Delivery System in a Rodent Model of Parkinson's Disease |
| Q36969304 | Correction of a Rat Model of Parkinson's Disease by Coexpression of Tyrosine Hydroxylase and Aromatic Amino Acid Decarboxylase from a Helper Virus-Free Herpes Simplex Virus Type 1 Vector |
| Q36085361 | Design of a single AAV vector for coexpression of TH and GCH1 to establish continuous DOPA synthesis in a rat model of Parkinson's disease |
| Q34233867 | Enhancement of cell-specific transgene expression from a Tet-Off regulatory system using a transcriptional amplification strategy in the rat brain |
| Q74268218 | Ephemeral gene medicine for the brain |
| Q40775660 | Evaluation of the tetracycline- and ecdysone-inducible systems for expression of neurotransmitter receptors in mammalian cells |
| Q40268859 | Gene delivery to differentiated neurotypic cells with RGD and HIV Tat peptide functionalized polymeric nanoparticles |
| Q36150495 | Gene therapy for Parkinson's disease using recombinant adeno-associated viral vectors |
| Q43109283 | Gene therapy for dopamine replacement in Parkinson's disease |
| Q37796024 | Gene therapy for dopamine replacement. |
| Q44383524 | Highly suppressible expression of single-chain interleukin-12 by doxycycline following adenoviral infection with a single-vector Tet-regulatory system |
| Q37460085 | In vivo gene regulation using tetracycline-regulatable systems |
| Q43244057 | Long-term inducible expression in striatal neurons from helper virus-free HSV-1 vectors that contain the tetracycline-inducible promoter system |
| Q42506402 | Modulation of neuronal survival and axonal growth in vivo by tetracycline-regulated neurotrophin expression. |
| Q33985663 | Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders |
| Q43710410 | Rat marrow stromal cells rapidly transduced with a self-inactivating retrovirus synthesize L-DOPA in vitro |
| Q36368045 | Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders. |
| Q34338244 | Recombinant proteins for neurodegenerative diseases: the delivery issue |
| Q36569912 | Regulatable gene expression systems for gene therapy |
| Q36157542 | Regulatable gene expression systems for gene therapy applications: progress and future challenges |
| Q40753328 | Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector |
| Q31045537 | Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer |
| Q36853737 | Subthalamic hGAD65 gene therapy and striatum TH gene transfer in a Parkinson's disease rat model |
| Q36316660 | Synaptic sprouting increases the uptake capacities of motoneurons in amyotrophic lateral sclerosis mice |
| Q44612690 | Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase |
| Q39458294 | Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease |
| Q34085502 | Tetracycline-regulated gene expression in the brain |
| Q35039021 | The degradation of amyloid beta as a therapeutic strategy in Alzheimer's disease and cerebrovascular amyloidoses |
| Q39617892 | The vesicular glutamate transporter-1 upstream promoter and first intron each support glutamatergic-specific expression in rat postrhinal cortex |
| Q40732042 | Viral gene delivery |
| Q34471754 | Viral-based modelling and correction of neurodegenerative diseases by RNA interference. |
Search more.