Correction of a Rat Model of Parkinson's Disease by Coexpression of Tyrosine Hydroxylase and Aromatic Amino Acid Decarboxylase from a Helper Virus-Free Herpes Simplex Virus Type 1 Vector

scientific article published on March 20, 2003

Correction of a Rat Model of Parkinson's Disease by Coexpression of Tyrosine Hydroxylase and Aromatic Amino Acid Decarboxylase from a Helper Virus-Free Herpes Simplex Virus Type 1 Vector is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1089/104303403321467180
P953full work available at URLhttp://www.liebertpub.com/doi/pdf/10.1089/104303403321467180
https://doi.org/10.1089/104303403321467180
https://europepmc.org/articles/PMC2581862
https://europepmc.org/articles/pmc2581862?pdf=render
https://europepmc.org/articles/PMC2581862?pdf=render
P932PMC publication ID2581862
P698PubMed publication ID12691607
P5875ResearchGate publication ID10807409

P50authorAlfred I GellerQ64944560
P2093author name stringWei Zhang
Mei Sun
Guo-Rong Zhang
Lingxin Kong
Xiaodan Wang
Courtney Holmes
David S. Goldstein
P2860cites workReversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transferQ31045537
The rat dopamine D4 receptor: sequence, gene structure, and demonstration of expression in the cardiovascular systemQ31128775
Treatment of Parkinsonism With LevodopaQ34240368
Gene therapy for Parkinson's disease: determining the genes necessary for optimal dopamine replacement in rat modelsQ34298405
Cell therapyQ34467385
Long-term doxycycline-controlled expression of human tyrosine hydroxylase after direct adenovirus-mediated gene transfer to a rat model of Parkinson's disease.Q35734505
Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells.Q35870965
Genetically modified cells: applications for intracerebral graftingQ36705238
Dopamine cell replacement: Parkinson's diseaseQ37916270
Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's diseaseQ39519102
A tyrosine hydroxylase-neurofilament chimeric promoter enhances long-term expression in rat forebrain neurons from helper virus-free HSV-1 vectorsQ40838016
Regulation of dopamine production by genetically modified primary fibroblastsQ41061107
General strategy for constructing large HSV-1 plasmid vectors that co-express multiple genesQ42113935
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Generation of high-titer defective HSV-1 vectors using an IE 2 deletion mutant and quantitative study of expression in cultured cortical cells.Q42815788
Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylaseQ43185222
Significant behavioral recovery in Parkinson's disease model by direct intracerebral gene transfer using continuous injection of a plasmid DNA-liposome complexQ44553274
Developmental potential of quail dorsal root ganglion cells analyzed in vitro and in vivo.Q44933058
HSV-1 vector mediated neuronal gene delivery. Strategies for molecular neuroscience and neurologyQ45111676
Fifty-one kilobase HSV-1 plasmid vector can be packaged using a helper virus-free system and supports expression in the rat brainQ45744857
Improved titers for helper virus-free herpes simplex virus type 1 plasmid vectors by optimization of the packaging protocol and addition of noninfectious herpes simplex virus-related particles (previral DNA replication enveloped particles) to the paQ45747563
Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.Q45756120
Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase enhance dopamine delivery after L-3, 4-dihydroxyphenylalanine administration in Parkinsonian rats.Q45857411
Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblastsQ45877347
Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expressionQ45881013
L-Dopa and dopamine-producing gene cassettes for gene therapy approaches to Parkinson's diseaseQ45881504
Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease.Q45884094
A 6-hydroxydopamine-induced selective parkinsonian rat modelQ46617652
Modulation of rat rotational behavior by direct gene transfer of constitutively active protein kinase C into nigrostriatal neurons.Q48455595
An HSV-1 vector containing the rat tyrosine hydroxylase promoter enhances both long-term and cell type-specific expression in the midbrainQ48723498
Circling behavior in rats with partial, unilateral nigro-striatal lesions: Effect of amphetamine, apomorphine, and DOPAQ57913305
Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's diseaseQ64383353
Striatal neurons with aromatic L-amino acid decarboxylase-like immunoreactivity in the ratQ69683841
Behavioral effects and gene delivery in a rat model of Parkinson's diseaseQ71967787
Improved assay for plasma dihydroxyphenylacetic acid and other catechols using high-performance liquid chromatography with electrochemical detectionQ72522228
Estimation of striatal dopamine spillover and metabolism in vivoQ73144506
[Comparison of the immune response to gene transfer into the rat brain with helper or helper virus-free HSV-1 vectors]Q78948957
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectgeneticsQ7162
Parkinson's diseaseQ11085
vector-borne diseaseQ2083837
molecular medicineQ3523816
genetic vectorQ427389
Herpes simplex virus type 1Q655331
P304page(s)415-424
P577publication date2003-03-01
2003-03-20
P1433published inHuman Gene TherapyQ15757580
P1476titleCorrection of a rat model of Parkinson's disease by coexpression of tyrosine hydroxylase and aromatic amino acid decarboxylase from a helper virus-free herpes simplex virus type 1 vector
Correction of a Rat Model of Parkinson's Disease by Coexpression of Tyrosine Hydroxylase and Aromatic Amino Acid Decarboxylase from a Helper Virus-Free Herpes Simplex Virus Type 1 Vector
P478volume14

Reverse relations

cites work (P2860)
Q38669532A 16 bp upstream sequence from the rat tyrosine hydroxylase promoter supports long-term expression from a neurofilament promoter, in a helper virus-free HSV-1 vector system
Q40305783A helper virus-free HSV-1 vector containing the vesicular glutamate transporter-1 promoter supports expression preferentially in VGLUT1-containing glutamatergic neurons
Q47300209And Then There Was Light: Perspectives of Optogenetics for Deep Brain Stimulation and Neuromodulation
Q38532388Antibody-mediated targeted gene transfer of helper virus-free HSV-1 vectors to rat neocortical neurons that contain either NMDA receptor 2B or 2A subunits
Q39685068Antibody-mediated targeted gene transfer to NMDA NR1-containing neurons in rat neocortex by helper virus-free HSV-1 vector particles containing a chimeric HSV-1 glycoprotein C-staphylococcus A protein
Q36969314Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behaviora
Q36969309Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease
Q33327584Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles
Q55418920Gene Therapy for Parkinson's Disease, An Update.
Q37796024Gene therapy for dopamine replacement.
Q35206326Gene therapy progress and prospects: Parkinson's disease
Q40164850Glutamatergic or GABAergic neuron-specific, long-term expression in neocortical neurons from helper virus-free HSV-1 vectors containing the phosphate-activated glutaminase, vesicular glutamate transporter-1, or glutamic acid decarboxylase promoter
Q36897379HSV-1 amplicon vectors: a promising and versatile tool for gene delivery.
Q36288901HSV-1-based amplicon vectors: design and applications
Q39923388Herpes Virus Amplicon Vectors
Q35863367Herpes simplex virus-based vectors
Q39756417Immobilized cobalt affinity chromatography provides a novel, efficient method for herpes simplex virus type 1 gene vector purification
Q33468717Improved long-term expression from helper virus-free HSV-1 vectors packaged using combinations of mutated HSV-1 proteins that include the UL13 protein kinase and specific components of the VP16 transcriptional complex
Q41820330Improved spatial learning in aged rats by genetic activation of protein kinase C in small groups of hippocampal neurons
Q57020987In vivo methods for acute modulation of gene expression in the central nervous system
Q40196434Isolation of an enhancer from the rat tyrosine hydroxylase promoter that supports long-term, neuronal-specific expression from a neurofilament promoter, in a helper virus-free HSV-1 vector system
Q43244057Long-term inducible expression in striatal neurons from helper virus-free HSV-1 vectors that contain the tetracycline-inducible promoter system
Q43211527Long-term transgene expression in mouse neural progenitor cells modified with phiC31 integrase
Q42141797Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
Q41571273Overexpression of either lysine-specific demethylase-1 or CLOCK, but not Co-Rest, improves long-term expression from a modified neurofilament promoter, in a helper virus-free HSV-1 vector system
Q26824184Parkinson's disease: gene therapies
Q36853737Subthalamic hGAD65 gene therapy and striatum TH gene transfer in a Parkinson's disease rat model
Q24298406The assays of activities and function of TH, AADC, and GCH1 and their potential use in ex vivo gene therapy of PD
Q39617892The vesicular glutamate transporter-1 upstream promoter and first intron each support glutamatergic-specific expression in rat postrhinal cortex
Q42052125Understanding and prevention of "therapy-" induced dyskinesias
Q33908524Use of the 2A peptide for generation of multi-transgenic pigs through a single round of nuclear transfer.
Q37946113Viral vectors for gene delivery to the central nervous system

Search more.