| scholarly article | Q13442814 |
| P50 | author | Un Jung Kang | Q64198619 |
| P2093 | author name string | K Hatakeyama | |
| S Milstien | |||
| J B Becker | |||
| C Bencsics | |||
| S R Wachtel | |||
| P2860 | cites work | Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector | Q24293730 |
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| An HSV-1 vector expressing tyrosine hydroxylase causes production and release of L-dopa from cultured rat striatal cells | Q36969336 | ||
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| Regulation of dopamine production by genetically modified primary fibroblasts | Q41061107 | ||
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| The stability of endogenous tyrosine hydroxylase protein in PC-12 cells differs from that expressed in mouse fibroblasts by gene transfer | Q41486178 | ||
| Tetrahydrobiopterin is required for cytokine-induced nitric oxide production in a murine macrophage cell line (RAW 264) | Q41588224 | ||
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| L-3,4-dihydroxyphenylalanine synthesis by genetically modified Schwann cells | Q41694260 | ||
| Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively prese | Q41743585 | ||
| Use of microdialysis for monitoring tyrosine hydroxylase activity in the brain of conscious rats | Q41764872 | ||
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| Tetrahydrobiopterin turnover in cultured rat sympathetic neurons: developmental profile, pharmacologic sensitivity, and relationship to norepinephrine synthesis | Q42453570 | ||
| In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum | Q42831252 | ||
| Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase | Q43185222 | ||
| The use of adenovirus vectors for intracerebral grafting of transfected nervous cells. | Q44038508 | ||
| Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system. | Q44128835 | ||
| Neural-targeted gene therapy for rodent and primate hemiparkinsonism | Q45866224 | ||
| Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. | Q45876510 | ||
| Morphological and neurochemical features of cultured primary skin fibroblasts of Fischer 344 rats following striatal implantation | Q46012400 | ||
| Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce l-dopa | Q46578408 | ||
| Effect of (6R)- and (6S)-tetrahydrobiopterin on L-3,4-dihydroxyphenylalanine (DOPA) formation in NRK fibroblasts transfected with human tyrosine hydroxylase type 2 cDNA. | Q47795547 | ||
| L-3,4-dihydroxyphenylalanine-induced dopamine release in the striatum of intact and 6-hydroxydopamine-treated rats: differential effects of monoamine oxidase A and B inhibitors | Q48091297 | ||
| Entrance of tetrahydropterin derivatives in brain after peripheral administration: effect on biogenic amine metabolism | Q48224677 | ||
| Microdialysis monitoring of 3,4-dihydroxyphenylalanine accumulation after decarboxylase inhibition: a means to estimate in vivo changes in tyrosine hydroxylase activity of the rat locus ceruleus | Q48343114 | ||
| Tetrahydrobiopterin in Striatum: Localization in Dopamine Nerve Terminals and Role in Catecholamine Synthesis | Q49156811 | ||
| Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase. | Q51113198 | ||
| Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test | Q59574528 | ||
| Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease | Q64383353 | ||
| A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal | Q69890854 | ||
| Biopterin cofactor biosynthesis: GTP cyclohydrolase, neopterin and biopterin in tissues and body fluids of mammalian species | Q70654477 | ||
| Peripherally Administered Reduced Pterins Do Enter the Brain | Q70777153 | ||
| Analysis of reduced forms of biopterin in biological tissues and fluids | Q71136634 | ||
| Elevated body swing test: a new behavioral parameter for rats with 6-hydroxydopamine-induced hemiparkinsonism | Q71924117 | ||
| Behavioral effects and gene delivery in a rat model of Parkinson's disease | Q71967787 | ||
| Adrenal medulla grafts in the hemiparkinsonian rat: profile of behavioral recovery predicts restoration of the symmetry between the two striata in measures of pre- and postsynaptic dopamine function | Q72231242 | ||
| Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat | Q72534294 | ||
| Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats | Q72707580 | ||
| A RAPID AND SIMPLE RADIOASSAY FOR TYROSINE HYDROXYLASE ACTIVITY | Q77150560 | ||
| Biopterin cofactor and monoamine-synthesizing monooxygenases | Q84268874 | ||
| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4449-4456 | |
| P577 | publication date | 1996-07-01 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts | |
| P478 | volume | 16 |
| Q34656049 | Advances in gene therapy for movement disorders. |
| Q44547034 | Behavioral correction of Parkinsonian rats following the transplantation of immortalized fibroblasts genetically modified with TH and GCH genes |
| Q48240667 | Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions |
| Q45756120 | Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease. |
| Q36969314 | Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behaviora |
| Q44123143 | Comparison of epidermal keratinocytes and dermal fibroblasts as potential target cells for somatic gene therapy of phenylketonuria |
| Q37406055 | Consideration of gene therapy for paediatric neurotransmitter diseases |
| Q36969304 | Correction of a Rat Model of Parkinson's Disease by Coexpression of Tyrosine Hydroxylase and Aromatic Amino Acid Decarboxylase from a Helper Virus-Free Herpes Simplex Virus Type 1 Vector |
| Q36085361 | Design of a single AAV vector for coexpression of TH and GCH1 to establish continuous DOPA synthesis in a rat model of Parkinson's disease |
| Q40827772 | Development of a skin-based metabolic sink for phenylalanine by overexpression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes |
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| Q64381079 | Dopa-producing astrocytes generated by adenoviral transduction of human tyrosine hydroxylase gene: in vitro study and transplantation to hemiparkinsonian model rats |
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| Q33837123 | Gene therapy in the CNS. |
| Q33899454 | Gene transfer into neurones for the molecular analysis of behaviour: focus on herpes simplex vectors. |
| Q42113935 | General strategy for constructing large HSV-1 plasmid vectors that co-express multiple genes |
| Q35216671 | Herpes simplex virus vectors for Parkinson's disease |
| Q64789924 | Herpes simplex virus vectors for gene therapy in Parkinson's disease and other diseases of the nervous system |
| Q33614725 | Human nerual stem cells for brain repair |
| Q35734505 | Long-term doxycycline-controlled expression of human tyrosine hydroxylase after direct adenovirus-mediated gene transfer to a rat model of Parkinson's disease. |
| Q35550669 | Metabolic Engineering: Advances in Modeling and Intervention in Health and Disease |
| Q30493158 | Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson's disease |
| Q34098326 | Potential use of marrow stromal cells as therapeutic vectors for diseases of the central nervous system |
| Q54041672 | Preferential resistance of dopaminergic neurons to glutathione depletion in a reconstituted nigrostriatal system. |
| Q44374758 | Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in an NMDA, AMPA/kainate, and metabotropic glutamate receptor-dependent manner. |
| Q28138668 | Prospects for new restorative and neuroprotective treatments in Parkinson's disease |
| Q43710410 | Rat marrow stromal cells rapidly transduced with a self-inactivating retrovirus synthesize L-DOPA in vitro |
| Q60950137 | Repairing the Brain: Gene Therapy |
| Q31045537 | Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer |
| Q36853737 | Subthalamic hGAD65 gene therapy and striatum TH gene transfer in a Parkinson's disease rat model |
| Q28273702 | Tyrosine hydroxylase and Parkinson's disease |
| Q45857411 | Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase enhance dopamine delivery after L-3, 4-dihydroxyphenylalanine administration in Parkinsonian rats. |
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