Herpes simplex virus vectors for Parkinson's disease

scientific article

Herpes simplex virus vectors for Parkinson's disease is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0074-7742(03)01010-9
P698PubMed publication ID12968539

P2093author name stringDavid S Latchman
P2860cites workFamilial Parkinson disease gene product, parkin, is a ubiquitin-protein ligaseQ22254584
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonismQ24309753
GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neuronsQ24336322
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodiesQ24653247
Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's diseaseQ64383353
The genetics of Parkinson's diseaseQ64782384
Brn-3a activates the expression of Bcl-x(L) and promotes neuronal survival in vivo as well as in vitroQ73683636
Mutation in the alpha-synuclein gene identified in families with Parkinson's diseaseQ27860459
Alpha-synuclein in Lewy bodiesQ27860680
Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Q28202629
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine systemQ28594502
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's diseaseQ29547175
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disordersQ29614754
Association between early-onset Parkinson's disease and mutations in the parkin geneQ29615733
A Drosophila model of Parkinson's diseaseQ29617052
Transplantation of embryonic dopamine neurons for severe Parkinson's diseaseQ29617304
Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant gliomaQ33905047
Gene delivery and gene therapy with herpes simplex virus-based vectorsQ34179305
Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouseQ34308944
Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequenceQ34779144
Human gene therapy comes of age.Q36220668
Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivoQ36457858
Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.Q36561684
Construction and characterization of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expressionQ36827546
Herpes simplex virus type 1 ICP27 is an essential regulatory protein.Q36904843
Herpes simplex virus Vmw65-octamer binding protein interaction: a paradigm for combinatorial control of transcriptionQ38310979
Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factorQ38336118
An inquiry into the mechanisms of herpes simplex virus latencyQ39159400
Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's diseaseQ39519102
Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defectsQ39550929
Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous systemQ39591444
Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degenerationQ40805293
Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivoQ40814855
Genetic dissection of familial Parkinson's diseaseQ40837761
Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's diseaseQ40929764
High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5.Q40954651
Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vectorQ40973614
Gene transfer to neurons using herpes simplex virus-based vectorsQ41132657
Prospects for gene therapy in Parkinson's diseaseQ41159915
Biology of glial cell line-derived neurotrophic factor (GDNF): implications for the use of GDNF to treat Parkinson's diseaseQ41169846
Therapeutic potentials for glial cell line-derived neurotrophic factor (GDNF) based upon pharmacological activities in the CNS.Q41186665
Fetal nigral transplantation as a therapy for Parkinson's diseaseQ41367101
Potential use of herpes simplex virus (HSV) vectors for gene therapy of neurological disordersQ41543685
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylaseQ43185222
Pathways of viral gene expression during acute neuronal infection with HSV-1Q44933537
Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.Q45756120
Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblastsQ45877347
Intracerebral recombinant HSV-1 vector does not reactivate latent HSV-1.Q45885582
A latent, nonpathogenic HSV-1-derived vector stably expresses beta-galactosidase in mouse neuronsQ46135759
Induction of midbrain dopaminergic neurons by Sonic hedgehogQ46258125
The ubiquitin pathway in Parkinson's diseaseQ48015939
Decreased reporter gene expression during latent infection with HSV LAT promoter constructs.Q54647282
Synucleins in synaptic plasticity and neurodegenerative disordersQ62055336
P921main subjectParkinson's diseaseQ11085
vector-borne diseaseQ2083837
P304page(s)223-241
P577publication date2003-01-01
P1433published inInternational Review of NeurobiologyQ15754273
P1476titleHerpes simplex virus vectors for Parkinson's disease
P478volume55