Prolonged survival of a patient with metastatic leptomeningeal melanoma treated with BRAF inhibition-based therapy: a case report

scientific article published on 13 May 2015

Prolonged survival of a patient with metastatic leptomeningeal melanoma treated with BRAF inhibition-based therapy: a case report is …
instance of (P31):
scholarly articleQ13442814
case reportQ2782326

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P6179Dimensions Publication ID1049337760
P356DOI10.1186/S12885-015-1391-X
P932PMC publication ID4440312
P698PubMed publication ID25962795
P5875ResearchGate publication ID276210109

P2093author name stringKevin B Kim
Dae Won Kim
Marta Penas-Prado
Ashok J Kumar
Edelyn Barcena
Michelle L Rohlfs
Urvi N Mehta
P2860cites workLeptomeningeal carcinomatosis. Presenting features and prognostic factors.Q50990635
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Leptomeningeal melanomatosis: stabilization of disease due to radiation, temozolomide and intrathecal liposomal cytarabineQ84516618
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Junctions between intimately apposed cell membranes in the vertebrate brainQ24682725
Improved overall survival in melanoma with combined dabrafenib and trametinibQ27853091
Mutations of the BRAF gene in human cancerQ27860760
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trialQ29614756
Leptomeningeal metastases in the MRI era.Q33853342
Combined BRAF (Dabrafenib) and MEK inhibition (Trametinib) in patients with BRAFV600-mutant melanoma experiencing progression with single-agent BRAF inhibitorQ34484174
Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigmQ34632917
Leptomeningeal metastasis in melanoma: a prospective clinical study of nine patientsQ34645509
Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanomaQ34664981
Neoplastic meningitis from solid tumors: new diagnostic and therapeutic approaches.Q35584731
Carcinomatous meningitis: Leptomeningeal metastases in solid tumorsQ36851197
Prognostic factors and outcomes in patients with leptomeningeal melanomatosisQ37284337
Long-term stabilization of leptomeningeal disease with whole-brain radiation therapy in a patient with metastatic melanoma treated with vemurafenib: a case reportQ37431085
Delayed but Complete Response following Oral Temozolomide Treatment in Melanoma Leptomeningeal CarcinomatosisQ42720641
Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trialQ44442912
Vemurafenib for leptomeningeal melanomatosis.Q45941209
Malignant melanoma and central nervous system metastases: incidence, diagnosis, treatment and survivalQ48170656
Quantitative Study of Blood.Brain Barrier Permeability Changes after Experimental Whole-Brain RadiationQ48552848
Clinical and radiological response of leptomeningeal melanoma after whole brain radiotherapy and ipilimumabQ48553169
Influence of radiation on the blood-brain barrier and optimum time of chemotherapyQ48844058
Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumorsQ48857140
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)400
P577publication date2015-05-13
P1433published inBMC CancerQ326300
P1476titleProlonged survival of a patient with metastatic leptomeningeal melanoma treated with BRAF inhibition-based therapy: a case report
P478volume15

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cites work (P2860)
Q26769870Combination therapy with BRAF and MEK inhibitors for melanoma: latest evidence and place in therapy
Q90669166Contemporary Multidisciplinary Management of Sinonasal Mucosal Melanoma
Q49556867Dabrafenib plus trametinib for compassionate use in metastatic melanoma: A STROBE-compliant retrospective observational postauthorization study.
Q47133535Leptomeningeal Disease and the Evolving Role of Molecular Targeted Therapy and Immunotherapy
Q48246291Leptomeningeal melanoma-A case series in the era of modern systemic therapy
Q30251581Managing leptomeningeal melanoma metastases in the era of immune and targeted therapy
Q38807942Melanoma central nervous system metastases: current approaches, challenges, and opportunities
Q55327976Neoplastic meningitis in solid tumors: from diagnosis to personalized treatments.
Q91280474Neurologic complications of melanoma
Q64118762Targeted Therapy After Brain Radiotherapy for BRAF-Mutated Melanoma With Extensive Ependymal Disease With Prolonged Survival: Case Report and Review of the Literature

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