| P50 | author | Frederica L Theodoulou | Q56439256 |
| | Ronald J A Wanders | Q87619350 |
| | Stephan Kemp | Q43188189 |
| P2860 | cites work | Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy | Q22009167 |
| | Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters | Q22010760 |
| | PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis | Q22253284 |
| | Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p | Q22253967 |
| | Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters | Q24290919 |
| | Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes | Q24291444 |
| | Targeting of the human adrenoleukodystrophy protein to the peroxisomal membrane by an internal region containing a highly conserved motif | Q24297381 |
| | Role of Pex19p in the targeting of PMP70 to peroxisome | Q24298579 |
| | The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy | Q24300003 |
| | The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells | Q24302137 |
| | PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins | Q24304129 |
| | Adrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations | Q24307632 |
| | Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p | Q24307906 |
| | Lack of adrenoleukodystrophy protein enhances oligodendrocyte disturbance and microglia activation in mice with combined Abcd1/Mag deficiency | Q50276649 |
| | Hydrophobic regions adjacent to transmembrane domains 1 and 5 are important for the targeting of the 70-kDa peroxisomal membrane protein. | Q50667468 |
| | Mouse liver PMP70 and ALDP: homomeric interactions prevail in vivo. | Q54544308 |
| | Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy | Q57387363 |
| | Predictions of a 2-locus model for disease heterogeneity: application to adrenoleukodystrophy | Q67986208 |
| | Effects of two peroxisome proliferators (ciprofibrate and fenofibrate) on peroxisomal membrane proteins and dihydroxyacetone-phosphate acyl-transferase activity in rat liver | Q70645588 |
| | Adrenoleukodystrophy: impaired oxidation of very long chain fatty acids in white blood cells, cultured skin fibroblasts, and amniocytes | Q71369133 |
| | Adrenoleukodystrophy: the restoration of peroxisomal beta-oxidation by transfection of normal cDNA | Q72269462 |
| | Expression of the adrenoleukodystrophy protein in the human and mouse central nervous system | Q73394362 |
| | Analysis of very long-chain fatty acids using electrospray ionization mass spectrometry | Q73651208 |
| | Adrenoleukodystrophy: incidence, new mutation rate, and results of extended family screening | Q73777797 |
| | Lovastatin for X-linked adrenoleukodystrophy | Q77207441 |
| | Retroviral-mediated adrenoleukodystrophy-related gene transfer corrects very long chain fatty acid metabolism in adrenoleukodystrophy fibroblasts: implications for therapy | Q77369612 |
| | Probing substrate-induced conformational alterations in adrenoleukodystrophy protein by proteolysis | Q81342480 |
| | X-linked adrenoleukodystrophy phenotype is independent of ABCD2 genotype | Q82205555 |
| | The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters | Q24308754 |
| | Identification of a fourth half ABC transporter in the human peroxisomal membrane | Q24312900 |
| | Differential substrate specificities of human ABCD1 and ABCD2 in peroxisomal fatty acid β-oxidation | Q24314446 |
| | Live cell FRET microscopy: homo- and heterodimerization of two human peroxisomal ABC transporters, the adrenoleukodystrophy protein (ALDP, ABCD1) and PMP70 (ABCD3) | Q24316602 |
| | The peroxisomal receptor Pex19p forms a helical mPTS recognition domain | Q24318137 |
| | Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters | Q24321939 |
| | Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy | Q24338719 |
| | Histone deacetylases (HDACs): characterization of the classical HDAC family | Q24535587 |
| | The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae | Q24562152 |
| | A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern | Q24567552 |
| | Current and future pharmacological treatment strategies in X-linked adrenoleukodystrophy | Q24618949 |
| | A quantitative atlas of mitotic phosphorylation | Q24646817 |
| | Altered expression of ALDP in X-linked adrenoleukodystrophy | Q24671055 |
| | Spectrum of mutations in the gene encoding the adrenoleukodystrophy protein | Q24672329 |
| | Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system | Q27935936 |
| | Identification of a common PEX1 mutation in Zellweger syndrome | Q28142124 |
| | ABC Transporters: From Microorganisms to Man | Q28181688 |
| | Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome | Q28207783 |
| | ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1) | Q28217842 |
| | Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism | Q28236420 |
| | Biochemistry of mammalian peroxisomes revisited | Q28244563 |
| | The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily | Q28255277 |
| | Genomic organization of the 70-kDa peroxisomal membrane protein gene (PXMP1) | Q28266065 |
| | Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins | Q28271907 |
| | Correction by gene expression of biochemical abnormalities in fibroblasts from Zellweger patients | Q28285599 |
| | X-linked adrenoleukodystrophy (ALD): a novel mutation of the ALD gene in 6 members of a family presenting with 5 different phenotypes | Q28304894 |
| | Nucleotide-induced conformational changes of PMP70, an ATP binding cassette transporter on rat liver peroxisomal membranes | Q28564490 |
| | Fenofibrate differently alters expression of genes encoding ATP-binding transporter proteins of the peroxisomal membrane | Q28582740 |
| | 70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins | Q28583012 |
| | Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane | Q29871130 |
| | Mirror expression of adrenoleukodystrophy and adrenoleukodystrophy related genes in mouse tissues and human cell lines | Q32064197 |
| | Farnesylation of pex19p is required for its structural integrity and function in peroxisome biogenesis | Q41897979 |
| | Pim-1 kinase protects P-glycoprotein from degradation and enables its glycosylation and cell surface expression | Q42163903 |
| | A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis. | Q42443097 |
| | Lipid rafts are essential for peroxisome biogenesis in HepG2 cells | Q42947246 |
| | Lovastatin in X-linked adrenoleukodystrophy | Q43188143 |
| | Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha | Q43650859 |
| | Thyroid hormone induction of the adrenoleukodystrophy-related gene (ABCD2). | Q44449920 |
| | Evaluation of the therapeutic potential of PPARalpha agonists for X-linked adrenoleukodystrophy. | Q44679119 |
| | Visualization and quantitation of peroxisomes using fluorescent nanocrystals: treatment of rats and monkeys with fibrates and detection in the liver | Q44845014 |
| | The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression. | Q45862493 |
| | Interchromosomal duplications of the adrenoleukodystrophy locus: a phenomenon of pericentromeric plasticity | Q48048122 |
| | Identification of a two base pair deletion in five unrelated families with adrenoleukodystrophy: a possible hot spot for mutations | Q48080771 |
| | Head trauma can initiate the onset of adreno-leukodystrophy | Q48395242 |
| | The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture | Q48575949 |
| | Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy | Q48671536 |
| | Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage | Q48730826 |
| | Very-long-chain fatty acid metabolism in adrenoleukodystrophy protein-deficient mice | Q48894703 |
| | Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice | Q32159154 |
| | The role of peroxisomal ABC transporters in the mouse adrenal gland: the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage | Q33270660 |
| | X-linked adrenoleukodystrophy: genes, mutations, and phenotypes | Q33607735 |
| | X-linked adrenoleukodystrophy enigma: how does the ALD peroxisomal transporter mutation affect CNS glia? | Q33811095 |
| | Peroxisomal fatty acid alpha- and beta-oxidation in humans: enzymology, peroxisomal metabolite transporters and peroxisomal diseases | Q34253052 |
| | cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter. | Q34444000 |
| | Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. | Q34462811 |
| | Plasma very long chain fatty acids in 3,000 peroxisome disease patients and 29,000 controls | Q34488327 |
| | Evolution of phenotypes in adult male patients with X-linked adrenoleukodystrophy | Q34513788 |
| | Identification of novel SNPs of ABCD1, ABCD2, ABCD3, and ABCD4 genes in patients with X-linked adrenoleukodystrophy (ALD) based on comprehensive resequencing and association studies with ALD phenotypes. | Q34534494 |
| | Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts | Q34644825 |
| | Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column. | Q34734854 |
| | Mutational and protein analysis of patients and heterozygous women with X-linked adrenoleukodystrophy | Q35882708 |
| | Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator | Q36321611 |
| | A mouse model for X-linked adrenoleukodystrophy | Q36566796 |
| | Peroxisomal membrane permeability and solute transfer. | Q36625501 |
| | Pex19p interacts with Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris | Q36876929 |
| | Peroxisomal dynamics. | Q36959342 |
| | Lipid dependence of ABC transporter localization and function | Q37570698 |
| | Synthesis of a major integral membrane polypeptide of rat liver peroxisomes on free polysomes | Q37577356 |
| | Peroxisomes are oxidative organelles. | Q37643722 |
| | Peroxisomes, lipid metabolism and lipotoxicity. | Q37671940 |
| | Biochemical aspects of X-linked adrenoleukodystrophy. | Q37772226 |
| | X-linked adrenoleukodystrophy: Diagnostic and follow-up system in Japan | Q37808611 |
| | Regulation of ABC transporter function via phosphorylation by protein kinases | Q37813724 |
| | Localization of mRNAs for adrenoleukodystrophy and the 70 kDa peroxisomal (PMP70) proteins in the rat brain during post-natal development | Q38290251 |
| | Accurate DNA-based diagnostic and carrier testing for X-linked adrenoleukodystrophy | Q38327372 |
| | Function of the PEX19-binding site of human adrenoleukodystrophy protein as targeting motif in man and yeast. PMP targeting is evolutionarily conserved. | Q38329004 |
| | Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy. | Q38331491 |
| | Mutations affecting phosphorylation, ubiquitination and turnover of the ABC-transporter Ste6. | Q38360938 |
| | Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues. | Q39159964 |
| | Genetic classification and mutational spectrum of more than 600 patients with a Zellweger syndrome spectrum disorder | Q39638543 |
| | Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy | Q40698312 |
| | Regulation of transporter associated with antigen processing by phosphorylation. | Q41737446 |
| | Activity of the bile salt export pump (ABCB11) is critically dependent on canalicular membrane cholesterol content. | Q41843955 |
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 14 | |
| P304 | page(s) | 1753-1766 | |
| P577 | publication date | 2011-12-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P859 | sponsor | Purification and functional characterisation of COMATOSE a peroxisomal ABC transporter from Arabidopsis thaliana | Q63368418 |
| P1476 | title | Mammalian peroxisomal ABC transporters: from endogenous substrates to pathology and clinical significance | |
| P478 | volume | 164 | |