| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1006779716 |
| P356 | DOI | 10.1385/EP:14:4:277 |
| P698 | PubMed publication ID | 14739486 |
| P2093 | author name string | David E Millhorn | |
| Zachary Spicer | |||
| P2860 | cites work | The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis | Q22009936 |
| HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 | ||
| Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha | Q24291726 | ||
| C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation | Q24291783 | ||
| A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation | Q24294741 | ||
| Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia | Q45225100 | ||
| Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity | Q46189833 | ||
| Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway | Q47762057 | ||
| Hypoxia induces phosphorylation of the cyclic AMP response element-binding protein by a novel signaling mechanism | Q47791849 | ||
| Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression | Q48400092 | ||
| Regulation of Shaker-type potassium channels by hypoxia. Oxygen-sensitive K+ channels in PC12 cells | Q48888822 | ||
| Selective inhibition of a slow-inactivating voltage-dependent K+ channel in rat PC12 cells by hypoxia. | Q53966440 | ||
| Studies on the preaortal paraganglia of newborn rabbits | Q54132117 | ||
| Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1 | Q63565692 | ||
| Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB | Q68454790 | ||
| Biochemical studies on the release of catecholamines from the rat carotid body in vitro | Q69745304 | ||
| Increased Levels of Neuron‐Specific Enolase in PC 12 Pheochromocytoma Cells as a Result of Nerve Growth Factor Treatment | Q70913743 | ||
| Cell selective induction and transcriptional activation of immediate early genes by hypoxia | Q70983140 | ||
| Hypoxia-induced protein binding to O2-responsive sequences on the tyrosine hydroxylase gene | Q71743263 | ||
| Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig | Q72467778 | ||
| Induction of immediate early response genes by hypoxia. Possible molecular bases for systems adaptation to low pO2 | Q73066983 | ||
| EPAS1 trans-activation during hypoxia requires p42/p44 MAPK | Q73176153 | ||
| Exposure of cultured primary rat astrocytes to hypoxia results in intracellular glucose depletion and induction of glycolytic enzymes | Q73368028 | ||
| L-type Ca(2+) channel activation regulates induction of c-fos transcription by hypoxia | Q73746591 | ||
| Expression of dopamine D2 receptor in PC-12 cells and regulation of membrane conductances by dopamine | Q73847563 | ||
| Intracellular pathways linking hypoxia to activation of c-fos and AP-1 | Q73884995 | ||
| Hypoxia differentially regulates the mitogen- and stress-activated protein kinases. Role of Ca2+/CaM in the activation of MAPK and p38 gamma | Q73885018 | ||
| Stimulation of expression for the adenosine A2A receptor gene by hypoxia in PC12 cells. A potential role in cell protection | Q77985323 | ||
| Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions | Q24307776 | ||
| JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 | ||
| A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation | Q24312845 | ||
| Activation of cAMP and mitogen responsive genes relies on a common nuclear factor | Q24313652 | ||
| Nuclear protein CBP is a coactivator for the transcription factor CREB | Q24319801 | ||
| Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 | Q24320257 | ||
| Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation | Q24322099 | ||
| The PI3K-PDK1 connection: more than just a road to PKB | Q24531972 | ||
| Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. | Q24534053 | ||
| FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2 | Q24562050 | ||
| Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex | Q24654714 | ||
| Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway | Q24672316 | ||
| Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B | Q27860731 | ||
| Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
| HIF-1 and human disease: one highly involved factor | Q28144179 | ||
| Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation | Q28188357 | ||
| HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus | Q28191456 | ||
| A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells | Q28237789 | ||
| Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta | Q28255046 | ||
| Cyclin D1 is a nuclear protein required for cell cycle progression in G1 | Q28269145 | ||
| Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase | Q28283499 | ||
| Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine | Q28287650 | ||
| Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha | Q28507449 | ||
| Mesenchymal-epithelial transition in the developing metanephric kidney: gene expression study by differential display | Q28566419 | ||
| CBP associates with the p42/p44 MAPK enzymes and is phosphorylated following NGF treatment | Q28572730 | ||
| Angiotensin II's antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20 | Q28573451 | ||
| Calcium-dependent activation of Pyk2 by hypoxia | Q28575476 | ||
| Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells | Q28578972 | ||
| Hypoxia-inducible factor 2alpha binds to cobalt in vitro | Q28580816 | ||
| Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein | Q28647609 | ||
| Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily | Q41296563 | ||
| Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. | Q41461695 | ||
| Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells. | Q41495153 | ||
| CREB is activated by UVC through a p38/HOG-1-dependent protein kinase | Q42113864 | ||
| Neurotransmitter- and growth factor-induced cAMP response element binding protein phosphorylation in glial cell progenitors: role of calcium ions, protein kinase C, and mitogen-activated protein kinase/ribosomal S6 kinase pathway. | Q42528881 | ||
| Evidence for a PO2-sensitive K+ channel in the type-I cell of the rabbit carotid body | Q42646423 | ||
| Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts | Q42807624 | ||
| Hypoxia activates Akt and induces phosphorylation of GSK-3 in PC12 cells | Q43546852 | ||
| Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis | Q43569584 | ||
| The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells | Q43694144 | ||
| Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. | Q43778599 | ||
| Cytokines induce HIF-1 DNA binding and the expression of HIF-1-dependent genes in cultured rat enterocytes | Q44185449 | ||
| Hypoxia activates multiple transcriptional pathways in mouse pheochromocytoma cells | Q44220561 | ||
| CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases | Q45137410 | ||
| Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa | Q28776408 | ||
| The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation | Q29400446 | ||
| Cellular survival: a play in three Akts | Q29547806 | ||
| Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
| Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein | Q29615928 | ||
| Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133 | Q29617856 | ||
| Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human | Q29618981 | ||
| Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries | Q29618999 | ||
| The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
| Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain | Q29620169 | ||
| The regulation of AP-1 activity by mitogen-activated protein kinases | Q29620431 | ||
| Identification of hypoxia-responsive genes in a dopaminergic cell line by subtractive cDNA libraries and microarray analysis | Q30664150 | ||
| SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation. | Q30804501 | ||
| Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis | Q31012200 | ||
| SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons | Q31520793 | ||
| Organization and regulation of mitogen-activated protein kinase signaling pathways | Q33333640 | ||
| The effect of hypoxia on the catecholamine content of human fetal abdominal paraganglia and adrenal medulla | Q33476913 | ||
| Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP. | Q33781007 | ||
| Calcium regulation of neuronal gene expression | Q33944216 | ||
| siRNA-mediated gene silencing in vitro and in vivo. | Q34150604 | ||
| MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300 | Q34177495 | ||
| Chemotransduction in the carotid body: K+ current modulated by PO2 in type I chemoreceptor cells | Q34406527 | ||
| BNips: a group of pro-apoptotic proteins in the Bcl-2 family | Q35135756 | ||
| Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor | Q36063824 | ||
| Identification of a novel growth factor-responsive gene in vascular smooth muscle cells. | Q36749276 | ||
| Oxygen chemoreception by carotid body cells in culture | Q37679447 | ||
| Both the basal and inducible transcription of the tyrosine hydroxylase gene are dependent upon a cAMP response element. | Q38317474 | ||
| Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins | Q38322876 | ||
| Effects of hypoxia on tyrosine hydroxylase activity in rat carotid body | Q39270065 | ||
| Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo | Q39453609 | ||
| Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation | Q39631004 | ||
| Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway. | Q40023501 | ||
| The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels | Q40545374 | ||
| CREB: a mediator of long-term memory from mollusks to mammals | Q40630853 | ||
| Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines | Q40657735 | ||
| Novel regulation of p38gamma by dopamine D2 receptors during hypoxia | Q40855014 | ||
| O2-sensitive K+ channels: role of the Kv1.2 -subunit in mediating the hypoxic response | Q40882967 | ||
| Mitogen-activated protein kinase cascades and regulation of gene expression | Q41102936 | ||
| Sounding the alarm: protein kinase cascades activated by stress and inflammation | Q41106742 | ||
| Regulation of vascular endothelial growth factor by hypoxia and its modulation by the von Hippel-Lindau tumor suppressor gene | Q41131062 | ||
| Regulation of gene expression for tyrosine hydroxylase in oxygen sensitive cells by hypoxia | Q41131095 | ||
| MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP. | Q41150603 | ||
| Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. | Q41173912 | ||
| Membrane depolarization in PC-12 cells during hypoxia is regulated by an O2-sensitive K+ current | Q41180205 | ||
| Characterization of RAFTK, a novel focal adhesion kinase, and its integrin-dependent phosphorylation and activation in megakaryocytes | Q41184737 | ||
| Oxygen-sensing by ion channels and the regulation of cellular functions | Q41185790 | ||
| Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. | Q41205566 | ||
| P433 | issue | 4 | |
| P921 | main subject | phaeochromocytoma | Q536269 |
| oxygen sensing | Q69984017 | ||
| P304 | page(s) | 277-291 | |
| P577 | publication date | 2003-01-01 | |
| P1433 | published in | Endocrine Pathology | Q15757049 |
| P1476 | title | Oxygen sensing in neuroendocrine cells and other cell types: pheochromocytoma (PC12) cells as an experimental model | |
| P478 | volume | 14 |
| Q33994896 | Apparent PKA activity responds to intermittent hypoxia in bone cells: a redox pathway? |
| Q37594802 | Chemically induced pheochromocytomas in rats: mechanisms and relevance for human risk assessment |
| Q42703535 | Cytoprotective effects of fisetin against hypoxia-induced cell death in PC12 cells |
| Q28583376 | Down-regulation of interleukin 7 mRNA by hypoxia is calcium dependent |
| Q38518910 | Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes |
| Q35529017 | Hypoxia-inducible factor-1α regulates the expression of L-type voltage-dependent Ca(2+) channels in PC12 cells under hypoxia |
| Q47873015 | Melandrii Herba Extract Attenuates H₂O₂-Induced Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells and Scopolamine-Induced Memory Impairment in Mice. |
| Q36831552 | Molecular and cellular biology of pheochromocytomas and extra-adrenal paragangliomas |
| Q92738095 | Proapoptotic effects of 2,5‑hexanedione on pheochromocytoma cells via oxidative injury |
| Q90613964 | Schizandrin Protects against OGD/R-Induced Neuronal Injury by Suppressing Autophagy: Involvement of the AMPK/mTOR Pathway |
| Q38865088 | The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells. |
| Q62900074 | Transcriptome Profiling of Neuronal Model Cell PC12 from Rat Pheochromocytoma |
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