Connexin-43 hemichannels mediate cyclic ADP-ribose generation and its Ca2+-mobilizing activity by NAD+/cyclic ADP-ribose transport

scientific article published on 27 October 2011

Connexin-43 hemichannels mediate cyclic ADP-ribose generation and its Ca2+-mobilizing activity by NAD+/cyclic ADP-ribose transport is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.307645
P932PMC publication ID3247979
P698PubMed publication ID22033928

P2093author name stringYoung-Rae Lee
Uh-Hyun Kim
Jong-Suk Kim
Myung-Kwan Han
Ji-Hyun Yeom
Kwang-Hyun Park
Eun-Kyung Song
Yu-Ri Kim
So-Young Rah
Chae-Hwa Yoo
P2860cites workInteraction of two classes of ADP-ribose transfer reactions in immune signalingQ22253954
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivoQ28203353
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathologyQ28287124
Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomesQ28302379
Connexin 43 hemi channels mediate Ca2+-regulated transmembrane NAD+ fluxes in intact cellsQ31636101
Topology of CD38.Q33941877
Knock-down of the type 3 ryanodine receptor impairs sustained Ca2+ signaling via the T cell receptor/CD3 complexQ34152329
Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by PKC.Q35672465
Fc-receptor-mediated phagocytosis occurs in macrophages without an increase in average [Ca++]i.Q36214938
Cytosolic free calcium increases before and oscillates during frustrated phagocytosis in macrophagesQ36217222
Fc receptor-mediated phagocytosis occurs in macrophages at exceedingly low cytosolic Ca2+ levelsQ36218675
Calcium transients during Fc receptor-mediated and nonspecific phagocytosis by murine peritoneal macrophagesQ36532841
Sources of calcium in sea urchin eggs during the fertilization responseQ36781606
The increase in intracellular free calcium associated with IgG gamma 2b/gamma 1 Fc receptor-ligand interactions: role in phagocytosisQ37565921
Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalizationQ40772226
FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular traffickingQ41041395
Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptorQ41205257
Involvement of the multilineage CD38 molecule in a unique pathway of cell activation and proliferationQ41718287
Extracellular NAD is a regulator for FcgammaR-mediated phagocytosis in murine macrophagesQ42523193
Equilibrative and concentrative nucleoside transporters mediate influx of extracellular cyclic ADP-ribose into 3T3 murine fibroblastsQ42809637
A self-restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblastsQ42824644
Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cellsQ43298205
Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscleQ43917329
Ca(2+)-induced Ca2+ release in sea urchin egg homogenates: modulation by cyclic ADP-riboseQ44881338
Cyclic ADP-ribose as an endogenous regulator of the non-skeletal type ryanodine receptor Ca2+ channelQ48253956
Cyclic ADP-ribose in insulin secretion from pancreatic beta cellsQ48346388
Signal transduction by neutrophil immunoglobulin G Fc receptors. Dissociation of intracytoplasmic calcium concentration rise from inositol 1,4,5-trisphosphateQ54273778
T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytesQ59081818
Function of NAD glycohydrolase in ADP-ribose uptake from NAD by human erythrocytesQ70469008
A specific cyclic ADP-ribose antagonist inhibits cardiac excitation-contraction couplingQ71527202
The rapid purification of peritoneal exudate macrophages by ficoll (polysucrose) density gradient centrifugationQ71582149
Cyclic ADP-ribose: metabolism and calcium mobilizing functionQ72756811
The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranesQ77526453
Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+ increase are reciprocally modulated in rat cardiomyocytesQ79323417
P433issue52
P407language of work or nameEnglishQ1860
P304page(s)44480-44490
P577publication date2011-10-27
P1433published inJournal of Biological ChemistryQ867727
P1476titleConnexin-43 hemichannels mediate cyclic ADP-ribose generation and its Ca2+-mobilizing activity by NAD+/cyclic ADP-ribose transport
P478volume286

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