Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice

scientific article published on 12 December 2011

Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PNAS..10821117Q
P356DOI10.1073/PNAS.1112351109
P932PMC publication ID3248552
P698PubMed publication ID22160720
P5875ResearchGate publication ID51870562

P2093author name stringChun-Li Zhang
Song Qin
Menglu Liu
Wenze Niu
P2860cites workIdentification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrestQ24311735
A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cellsQ24322959
Mammalian Krüppel-Like Factors in Health and DiseasesQ24612560
Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiationQ24648756
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
Klf4 is a transcription factor required for establishing the barrier function of the skinQ28115084
Subcommissural organ, cerebrospinal fluid circulation, and hydrocephalusQ28204123
SCO-ping out the mechanisms underlying the etiology of hydrocephalusQ28241174
An extended transcriptional network for pluripotency of embryonic stem cellsQ28273615
Role of Sox2 in the development of the mouse neocortexQ28505312
Klf4 interacts directly with Oct4 and Sox2 to promote reprogrammingQ28508737
Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4Q28512536
When cilia go bad: cilia defects and ciliopathiesQ29547198
Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortexQ29616194
Expression of the human PAC1 receptor leads to dose-dependent hydrocephalus-related abnormalities in miceQ30477471
KLF family members regulate intrinsic axon regeneration ability.Q33899036
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.Q34128767
Congenital hydrocephalus in hy3 mice is caused by a frameshift mutation in Hydin, a large novel geneQ34193368
Ectopic expression of Kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrierQ34195392
Genetic defects in ciliary structure and functionQ34576108
A role for adult TLX-positive neural stem cells in learning and behaviourQ34743630
Transcriptional profiling of the cell cycle checkpoint gene krüppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesisQ35112786
Hydrocephalus and primary ciliary dyskinesiaQ35117859
Activation of postnatal neural stem cells requires nuclear receptor TLXQ35334539
HydrocephalusQ35737420
Timing is everything: making neurons versus glia in the developing cortexQ36811626
Cell types to order: temporal specification of CNS stem cellsQ37475395
Development of hydrocephalus in mice lacking SOCS7.Q37593683
Reactive astrocytosis, microgliosis and inflammation in rats with neonatal hydrocephalusQ39847155
Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis.Q45213360
GFAP promoter directs astrocyte-specific expression in transgenic miceQ48163933
Development of hydrocephalus in mice expressing the G(i)-coupled GPCR Ro1 RASSL receptor in astrocytes.Q48257693
A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells.Q48438463
Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalusQ48697963
Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.Q51921401
A core Klf circuitry regulates self-renewal of embryonic stem cells.Q51964604
Inducible production of interferon-gamma in the developing brain causes cerebellar dysplasia with activation of the Sonic hedgehog pathway.Q52085577
Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding.Q52165847
GFAP promoter elements required for region-specific and astrocyte-specific expressionQ80607573
P433issue52
P407language of work or nameEnglishQ1860
P921main subjecthydrocephalusQ193003
P304page(s)21117-21121
P577publication date2011-12-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleDysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice
P478volume108

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cites work (P2860)
Q41765220A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
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Q47381862An Image-Based miRNA screen identifies miRNA-135s as regulators of CNS axon growth and regeneration by targeting Krüppel-like factor 4.
Q28591066Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor
Q35647645Camk2a-Cre-mediated conditional deletion of chromatin remodeler Brg1 causes perinatal hydrocephalus
Q36424347Chronic Social Stress and Ethanol Increase Expression of KLF11, a Cell Death Mediator, in Rat Brain
Q28512938Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus
Q24338431Cross-talk between KLF4 and STAT3 regulates axon regeneration
Q33842969Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice
Q89459205Erythropoietin-mediated activation of aquaporin-4 channel for the treatment of experimental hydrocephalus
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Q52646137Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.
Q36855297Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling
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Q34478207In Vivo Expression of the PTB-deleted Odin Mutant Results in Hydrocephalus
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Q46485159KLF4 Knockdown Attenuates TBI-Induced Neuronal Damage through p53 and JAK-STAT3 Signaling
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