Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain

scientific article published on 20 November 2006

Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.01400-06
P932PMC publication ID1800685
P698PubMed publication ID17116690
P5875ResearchGate publication ID6680671

P2093author name stringEzio Bonvini
Ilona Reischl
Barbara Rellahan
Carmen Serrano
Karen DeBell
Laurie Graham
P2860cites workRasGRP links T-cell receptor signaling to RasQ22254082
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signalingQ22254087
Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signalingQ24291810
Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domainQ24297343
Recruitment and activation of PLCgamma1 in T cells: a new insight into old domainsQ24304214
Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptideQ24313456
Construction of an SH2 domain-binding site with mixed specificityQ24315793
SH2 domains recognize specific phosphopeptide sequencesQ27860748
Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domainsQ27934605
Interaction of elongation factor-1alpha and pleckstrin homology domain of phospholipase C-gamma 1 with activating its activityQ28206047
Transcription factors of the NFAT family: regulation and functionQ28237645
Stimulation of phospholipase C-gamma 1 membrane association by epidermal growth factorQ28610780
A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signalingQ28646434
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineQ29547239
A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytesQ30164553
Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction.Q30175330
src-homology 2 (SH2) domain ligation as an allosteric regulator: modulation of phosphoinositide-specific phospholipase C gamma 1 structure and activityQ30193694
Inhibitory effect of src homology (SH) 2/SH3 fragments of phospholipase C-gamma on the catalytic activity of phospholipase C isoforms. Identification of a novel phospholipase C inhibitor regionQ30195240
Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3.Q31032985
Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell lineQ33606123
Phospholipase C-gamma as a signal-transducing elementQ33783486
Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-gamma1.Q33934437
Physiological requirement for both SH2 domains for phospholipase C-gamma1 function and interaction with platelet-derived growth factor receptorsQ33958685
Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes.Q34012481
Phospholipase C-gamma1 in tumor progression.Q35175975
T cell receptor signaling: beyond complex complexesQ35745872
Tyrosine phosphorylation of phospholipase C-II in vitro by the epidermal growth factor receptor.Q36056666
Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and developmentQ36074211
Enhanced phospholipase C-gamma1 activity produced by association of independently expressed X and Y domain polypeptidesQ37424515
Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma1.Q40394372
Role of TGF alpha stimulation of the ERK, PI3 kinase and PLC gamma pathways in ovarian cancer growth and migration.Q40459394
Signal transmission between the plasma membrane and nucleus of T lymphocytesQ40642986
Differential roles of the Src homology 2 domains of phospholipase C-gamma1 (PLC-gamma1) in platelet-derived growth factor-induced activation of PLC-gamma1 in intact cellsQ40897812
Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis.Q41290962
Biochemical analysis of SH2 domain-mediated protein interactionsQ41387596
Phospholipase C-gamma1: regulation of enzyme function and role in growth factor-dependent signal transductionQ41551925
Inhibition of phosphoinositide hydrolysis and cell growth of Swiss 3T3 cells by myristoylated phospholipase C inhibitor peptidesQ42833989
Functional Reassembly of a Split PH DomainQ44412514
Point mutations in the split PLC-gamma1 PH domain modulate phosphoinositide binding.Q50783177
Overexpression of phospholipase C-gamma 1 in colorectal carcinomas is associated with overexpression of factors that bind its promoterQ71869416
The amino-terminal Src homology 2 domain of phospholipase C gamma 1 is essential for TCR-induced tyrosine phosphorylation of phospholipase C gamma 1Q74506147
Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulationQ78701794
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)854-863
P577publication date2006-11-20
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleIntramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain
P478volume27

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cites work (P2860)
Q39783628A double point mutation in PCL-gamma1 (Y509A/F510A) enhances Y783 phosphorylation and inositol phospholipid-hydrolyzing activity upon EGF stimulation
Q24299547CD300a is expressed on human B cells, modulates BCR-mediated signaling, and its expression is down-regulated in HIV infection
Q37371736Characterization of phospholipase C gamma enzymes with gain-of-function mutations
Q36884567Cooperative Control of Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling by an Unusual Array of Redundant Repressive Elements.
Q57752495Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR
Q48728903Expression of multiple Src family kinases in sea urchin eggs and their function in Ca2+ release at fertilization
Q35752316Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells
Q39606133Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2.
Q37106710Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane
Q28542511Phosphorylation site dynamics of early T-cell receptor signaling
Q27651805Rac Regulates Its Effector Phospholipase C 2 through Interaction with a Split Pleckstrin Homology Domain
Q35967631Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation
Q36831338Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?
Q27674480Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation
Q27674679Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor
Q31163835Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of rho kinases
Q34018800TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.
Q33804696Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors.
Q30588609The autoinhibitory C-terminal SH2 domain of phospholipase C-γ2 stabilizes B cell receptor signalosome assembly
Q36853305The regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/protein kinase Cδ cascade
Q36817584Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ

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