A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.

scientific article published on 8 March 2007

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI28920
P932PMC publication ID1810568
P698PubMed publication ID17347683

P50authorKaren VousdenQ6370108
Christine DufèsQ56953346
Daniele BergamaschiQ62727094
Kevin M RyanQ37834605
Andreas SchätzleinQ51629989
P2093author name stringXin Lu
Diane Crighton
Jim O'Prey
Helen S Bell
P2860cites workThe tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damageQ22010200
PUMA induces the rapid apoptosis of colorectal cancer cellsQ24291462
PUMA, a novel proapoptotic gene, is induced by p53Q24291463
ASPP proteins specifically stimulate the apoptotic function of p53Q24291844
ASPP1 and ASPP2: common activators of p53 family membersQ24305256
A model for p53-induced apoptosisQ24313374
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2Q27642888
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutationsQ27730815
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Surfing the p53 networkQ28032484
Induction of apoptosis in HeLa cells by trans-activation-deficient p53Q53461564
p63 and p73 are required for p53-dependent apoptosis in response to DNA damageQ59065672
Chemosensitivity linked to p73 functionQ73342473
53BP2 induces apoptosis through the mitochondrial death pathwayQ28237734
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor geneQ28250929
Tumor suppressor p53 is a direct transcriptional activator of the human bax geneQ28306186
Live or let die: the cell's response to p53Q29547663
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53Q29547773
p53-dependent apoptosis modulates the cytotoxicity of anticancer agentsQ29615031
Evolution of functions within the p53/p63/p73 family.Q34148139
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.Q34170068
The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization.Q34359755
The expression of iASPP in acute leukemiasQ34377630
On the shoulders of giants: p63, p73 and the rise of p53.Q34511214
p53, p63 and p73--solos, alliances and feuds among family membersQ34515770
Apoptosis: a link between cancer genetics and chemotherapyQ34520432
Therapeutic exploitation of the p53 pathwayQ34583882
p73: Friend or foe in tumorigenesisQ34770297
Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.Q34984251
TP53 family members and human cancersQ35078717
The ASPP family: deciding between life and death after DNA damageQ35082288
Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cellsQ35088549
Splicing DNA-damage responses to tumour cell death.Q35976600
p53 mutation heterogeneity in cancerQ36113160
RETRACTED: p73alpha regulation by Chk1 in response to DNA damageQ37056579
DNA-binding independent cell death from a minimal proapoptotic region of E2F-1.Q38313722
Relief of p53-mediated telomerase suppression by p73.Q38330053
Viral oncoproteins discriminate between p53 and the p53 homolog p73.Q39576424
Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors.Q40372923
Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cellsQ40410781
p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocationQ40614201
The lower-generation polypropylenimine dendrimers are effective gene-transfer agents.Q40710593
Episomal vectors rapidly and stably produce high-titer recombinant retrovirusQ42810400
The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.Q47603890
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)1008-1018
P577publication date2007-03-08
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleA p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo
P478volume117